Questions and Answers
What is the main reason for the diagnostic dilemma posed by fibro-osseous lesions?
Their histological resemblance with one another
Who plays a pivotal role in differentially diagnosing fibro-osseous lesions?
Oral pathologist, radiologist, and clinician
What is the aim of the chapter on fibro-osseous lesions?
To simplify the group of bony lesions and highlight the interdisciplinary approach in their management
What is the reason for ample scope for ambiguity in identification and classification of fibro-osseous lesions?
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What are some examples of benign fibro-osseous lesions (BFOLs)?
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What is the genetic cause of Fibrous Dysplasia (FD)?
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What are the clinical presentations of Fibrous Dysplasia (FD)?
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What do the radiographic features of Fibrous Dysplasia (FD) include?
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How do GNAS1 mutations help differentiate Fibrous Dysplasia (FD) from other fibro-osseous lesions?
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What are the clinical subtypes of Fibrous Dysplasia (FD)?
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At what age does craniofacial Fibrous Dysplasia (FD) commonly affect growing bones?
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Which bones are involved in craniofacial Fibrous Dysplasia (FD) patterns?
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What is the clinical case scenario 1 described in the text?
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Which investigative modalities are important for fibro-osseous lesions?
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Which type of treatment is indicated for fibrous dysplasia (FD) when there are functional deficits or significant cosmetic deformity?
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What is the histological appearance of fibrous dysplasia (FD)?
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Which of the following may be advised for patients with orbital dysplasia and decreasing visual acuity?
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What is the range of bone involvement in fibro-osseous lesions (FOL)?
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Which age group is most commonly affected by Ossifying Fibromas?
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What is the BFOL spectrum inclusive of?
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Where are Ossifying Fibromas more commonly seen?
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What is the recommended approach for early treatment of progressive sensory disturbances in craniofacial dysplasia?
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What is the preferred initial treatment option for Ossifying Fibromas?
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What is the role of non-surgical treatment for fibro-osseous lesions (FOL)?
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What is a common radiological appearance of Ossifying Fibromas?
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What may be challenging in the differential diagnosis of fibro-osseous lesions (FOL)?
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What is a characteristic feature of Ossifying Fibromas in younger age groups?
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What is the basis for treatment of fibro-osseous lesions (FOL)?
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What is the gender predominance for Ossifying Fibromas?
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What may be indicated for patients with orbital dysplasia and decreasing visual acuity?
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What is the nature of Cemento-Osseous Dysplasia?
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What is the recommended treatment approach for fibro-osseous lesions (FOL) when there are functional deficits or significant cosmetic deformity?
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With what other condition does Cemento-Osseous Dysplasia share clinical and histological similarities?
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What is the recommended treatment for progressive sensory disturbances in craniofacial dysplasia?
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What may be required for lesions exhibiting aggressive behavior and recurrence?
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What is a common radiological appearance of Cemento-Osseous Dysplasia?
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What is a characteristic feature of Ossifying Fibromas in adults?
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What is a common effect of Ossifying Fibromas on the mandible?
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Study Notes
Ossifying Fibroma and Cemento-Osseous Dysplasia in Maxillofacial Region
- Ossifying Fibromas primarily affect the dentate segment of the mandible and maxilla
- They are slow-growing in adults but aggressive in younger age groups, causing displacement of teeth
- Ossifying Fibromas demonstrate well-delineated or encapsulated cellular fibrous connective tissue with osseous products
- They are more commonly seen in the mandible (77%), especially in the molar region
- The peak age for Ossifying Fibromas is in the 3rd and 4th decades, with a strong female predominance (5:1)
- Radiologically, they appear as well-demarcated, unilocular, and can show a mixed radiolucent/radiopaque appearance
- Ossifying Fibromas can cause bowing of the mandible, thinning of the lower border, and resorption or divergence of roots
- Surgical curettage is a preferred initial treatment option for Ossifying Fibromas, as they can be easily shelled out from the surrounding bone
- The recurrence rate of Ossifying Fibromas is variable and unpredictable
- Cemento-Osseous Dysplasia is a non-neoplastic fibro-osseous lesion occurring in tooth-bearing areas of the jaws
- Cemento-Osseous Dysplasia shares clinical and histological similarities with other fibro-osseous lesions like fibrous dysplasia and ossifying fibroma
- Lesions exhibiting aggressive behavior and recurrence may require resection, and treatment depends on the location, age of the patient, and aggressiveness of the lesion
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