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Questions and Answers

What is the sum total of all chemical reactions that occur in the body?

Metabolism.

What are the building blocks that are used to create molecules in the body?

  • Amino acids (correct)
  • Sugars (correct)
  • Building blocks
  • All of the above

The importance of energy changes and electron transfer in metabolism are discussed in chapter ______ of Campbell and Reece.

15

Standard states are a set of agreed-upon conditions for measuring thermodynamic properties.

<p>True (A)</p> Signup and view all the answers

What is the standard state for pure solids and liquids?

<p>A pure substance.</p> Signup and view all the answers

What is the standard state for gases?

<p>An ideal gas at a pressure of one atmosphere.</p> Signup and view all the answers

What is the standard state for solutions?

<p>An ideal solution at a concentration of 1 mole per liter.</p> Signup and view all the answers

A negative Gibbs free energy change indicates that a reaction is spontaneous.

<p>True (A)</p> Signup and view all the answers

A positive Gibbs free energy change indicates that a reaction requires energy input.

<p>True (A)</p> Signup and view all the answers

Match the terms with their corresponding definitions.

<p>Exergonic = A reaction that releases energy Endergonic = A reaction that requires energy input Catabolism = The breakdown of large molecules into smaller ones Anabolism = The synthesis of larger molecules from smaller ones</p> Signup and view all the answers

Metabolism is dependent upon the ratios of concentrations of reactants and products in a reaction.

<p>True (A)</p> Signup and view all the answers

The standard pH for biological systems, which is typically used for measuring Gibbs free energy change in these systems, is 7.

<p>True (A)</p> Signup and view all the answers

The vast majority of metabolic reactions are simply reactions that harness energy from the environment.

<p>True (A)</p> Signup and view all the answers

What process captures energy from the sun and converts it into glucose?

<p>Photosynthesis</p> Signup and view all the answers

What is the process called when living organisms obtain energy from the breakdown of food molecules?

<p>Cellular respiration</p> Signup and view all the answers

Anabolic reactions typically require energy input, while catabolic reactions typically release energy.

<p>True (A)</p> Signup and view all the answers

What is the process called when an organism breaks down stored glycogen?

<p>Glycogenolysis</p> Signup and view all the answers

What is the process called when an organism synthesizes glycogen from glucose?

<p>Glycogenesis</p> Signup and view all the answers

The breakdown of glycogen requires the input of ATP.

<p>False (B)</p> Signup and view all the answers

Glycogen is a highly branched molecule.

<p>True (A)</p> Signup and view all the answers

What enzyme is responsible for the degradation of glycogen?

<p>Glycogen phosphorylase</p> Signup and view all the answers

What enzyme is responsible for the synthesis of glycogen?

<p>Glycogen synthase</p> Signup and view all the answers

Glycogenolysis occurs primarily in the liver and muscles.

<p>True (A)</p> Signup and view all the answers

The process of gluconeogenesis is the reversal of glycolysis.

<p>False (B)</p> Signup and view all the answers

Gluconeogenesis occurs primarily in the liver.

<p>True (A)</p> Signup and view all the answers

Gluconeogenesis is an energy-requiring process.

<p>True (A)</p> Signup and view all the answers

What are the three irreversible steps in glycolysis that are bypassed in gluconeogenesis?

<p>The conversion of pyruvate to phosphoenolpyruvate, the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate, and the phosphorylation of glucose to glucose 6-phosphate.</p> Signup and view all the answers

The pentose phosphate pathway is an alternative to glycolysis.

<p>True (A)</p> Signup and view all the answers

The pentose phosphate pathway is primarily involved in ATP production.

<p>False (B)</p> Signup and view all the answers

The pentose phosphate pathway can produce glucose 6-phosphate, which can then be used in glycolysis.

<p>True (A)</p> Signup and view all the answers

The pentose phosphate pathway is highly regulated to ensure that the body meets its needs for both NADPH and ATP.

<p>True (A)</p> Signup and view all the answers

Oxidative phosphorylation is the process of ATP production in the mitochondria.

<p>True (A)</p> Signup and view all the answers

The electron transport chain in the mitochondria is a series of redox reactions.

<p>True (A)</p> Signup and view all the answers

The proton gradient across the inner mitochondrial membrane is used to generate ATP.

<p>True (A)</p> Signup and view all the answers

The ATP synthase complex is a multi-subunit protein complex located in the inner mitochondrial membrane.

<p>True (A)</p> Signup and view all the answers

The P/O ratio represents the ratio of ATP molecules produced to oxygen atoms consumed in oxidative phosphorylation.

<p>True (A)</p> Signup and view all the answers

The chemiosmotic coupling theory explains how the proton gradient generated by the electron transport chain is used to drive ATP synthesis.

<p>True (A)</p> Signup and view all the answers

The ATP synthase complex is a rotary engine.

<p>True (A)</p> Signup and view all the answers

Respiratory inhibitors block electron transport in the electron transport chain, ultimately leading to the accumulation of reduced electron carriers.

<p>True (A)</p> Signup and view all the answers

Flashcards

Metabolism

The sum of all chemical reactions in a living organism, including energy-harnessing and molecule-building processes.

Energy Changes in Metabolism

The changes in energy associated with metabolic reactions, typically measured in standard states.

Standard State

A specific set of conditions (temperature, pressure, concentration) used as a reference point for measuring thermodynamic properties.

Standard State for Solids/Liquids

Pure substance.

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Standard State for Gases

Ideal gas at 1 atmosphere pressure.

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Standard State for Solutions

Ideal solution with a concentration of 1 mole per liter (1 molar).

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Gibbs Free Energy Change (∆G)

A measure of the energy available to do work at constant temperature and pressure.

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Standard Gibbs Free Energy Change (∆G°)

The Gibbs free energy change when all reactants and products are in their standard states.

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Spontaneous Reaction

A reaction that occurs without external input of energy.

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Negative ∆G

Indicates a spontaneous reaction that releases energy.

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Reaction Quotient (Q)

A ratio of product concentrations to reactant concentrations in any given moment.

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Glycolysis

A metabolic pathway that breaks down glucose for energy.

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Electron Transfer

The movement of electrons that releases energy in metabolic pathways.

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Metabolic Pathways

Series of linked chemical reactions that are important for metabolism

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Krebs Cycle

Cycle where breakdown of products occurs to release energy

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Electron Transport Chain

Chain of reactions involving electrons, where energy is released.

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Amino Acid Synthesis

Production of amino acids from other molecules.

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Lipid Oxidation

Breakdown of fats for energy.

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Lipid Synthesis

Creation of fats from other molecules.

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Nutrient Intake

Acquiring energy from food.

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Study Notes

Chapter 15: Metabolism

  • Metabolism is the sum total of all chemical reactions in the body, intended to harness energy and build molecules.
  • It encompasses processes like building amino acids and sugars.
  • Energy changes and electron transfer are important aspects of metabolism.
  • Glycolysis, the Krebs cycle, the electron transport chain, and the pentose phosphate pathway are discussed as introductory topics in the chapter.
  • Standard states are used to measure energy changes in chemical reactions.
  • Standard states vary for different states of matter (solids, liquids, gases, and solutions).
  • ΔG (change in free energy) is a measure of spontaneity.
    • Negative ΔG indicates a spontaneous reaction.
    • Positive ΔG indicates a non-spontaneous reaction.
  • Exergonic reactions release energy (negative ΔG), while endergonic reactions absorb energy (positive ΔG.)

Additional Topics

  • Biological molecules (proteins, carbohydrates, lipids, nucleic acids) are discussed.
  • The importance of energy.
  • The use of ATP as an energy currency.
  • Catabolic and anabolic reactions.
  • Oxidation and reduction reactions are explained.
  • Coenzyme functions.
  • Enzyme and coenzyme roles in glycolysis.
  • Cellular energy.
  • Biological oxidation-reduction reactions.
  • NAD+ and FAD participate in metabolic processes as coenzymes.
  • Oxidation and reduction reactions (NAD, FAD) in metabolism.

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