Fertilization, Cleavage & Implantation
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Questions and Answers

What is the primary function of the acrosome in spermatozoa during fertilization?

  • To provide energy for motility
  • To store genetic material
  • To facilitate the fusion with the oocyte (correct)
  • To assist in the capacitation process
  • Which part of the spermatozoon is primarily responsible for motility?

  • Tail (flagellum) (correct)
  • Head
  • Middle piece
  • Neck
  • What is the significance of the mitochondrial sheath in the spermatozoon?

  • It protects the genetic material
  • It enables the sperm to enter the oocyte
  • It assists in fertilization by regulating temperature
  • It provides energy necessary for sperm motility (correct)
  • Where does fertilization predominantly take place in the female reproductive system?

    <p>At the ampullary part of the uterine tube</p> Signup and view all the answers

    What is the main reason that mitochondria are inherited only from the mother?

    <p>Mitochondria in sperm are destroyed during fertilization</p> Signup and view all the answers

    What occurs during the capacitation phase of spermatozoa?

    <p>Sperm gain the ability to fertilize an ovum</p> Signup and view all the answers

    Which of the following statements best describes the structure of spermatozoa?

    <p>It is divided into a head, a middle piece containing mitochondria, and a tail divided into four regions</p> Signup and view all the answers

    What is the primary outcome if the neural tube does not fuse properly during the period of organogenesis?

    <p>Development of neural tube defects</p> Signup and view all the answers

    Which of the following describes the development of the chorion during the early weeks of pregnancy?

    <p>Formation of a smooth chorion as the villi degenerate</p> Signup and view all the answers

    What developmental stage is critical for the formation of major organs and organ systems?

    <p>Period of organogenesis</p> Signup and view all the answers

    Which of the following best describes the change in the villous structure from primary to tertiary villi?

    <p>Blood vessels form within the villous structure</p> Signup and view all the answers

    What is the role of neuroectodermal cells during the fusion of neural folds?

    <p>They create a neural crest between ectodermal layers</p> Signup and view all the answers

    What is the primary layer of the uterine endometrium called after the implantation of the blastocyst?

    <p>Decidua</p> Signup and view all the answers

    At what approximate age does the blastocyst undergo implantation?

    <p>6 days</p> Signup and view all the answers

    Which structure provides nourishment to the blastocyst while it is floating freely in the uterus?

    <p>Uterine secretions</p> Signup and view all the answers

    What is the sequence of the embryonic stages in the first week following fertilization, starting with the oocyte?

    <p>Oocyte, fertilization, mitotic division, blastocyst</p> Signup and view all the answers

    Which layer of the trophoblast is responsible for the rapid expansion and the formation of finger-like processes?

    <p>Syncytiotrophoblast</p> Signup and view all the answers

    What happens when the implantation of the blastocyst extends deeper into the uterine tissue?

    <p>It leads to abnormal implantation.</p> Signup and view all the answers

    What is the function of the syncytiotrophoblast after implantation?

    <p>It produces enzymes that erode uterine tissues.</p> Signup and view all the answers

    What marks the transition from a primary follicle to a preovulatory follicle?

    <p>Expansion of the antrum</p> Signup and view all the answers

    What is the maximum number of blastomeres in a morula stage, approximately 3 days after fertilization?

    <p>16</p> Signup and view all the answers

    What characterizes placenta previa during delivery?

    <p>The placenta is delivered before the fetus.</p> Signup and view all the answers

    What is the primary function of the syncytiotrophoblast during the second week of development?

    <p>To form the outer layer of the placenta.</p> Signup and view all the answers

    Which layers differentiate from the inner cell mass of the blastocyst?

    <p>Epiblast and hypoblast.</p> Signup and view all the answers

    What initiates the maternal blood supply to the lacunae in the syncytiotrophoblast?

    <p>Erosion of maternal tissues.</p> Signup and view all the answers

    What structure fills the space between the trophoblast and the amnion during the second week of development?

    <p>Extraembryonic mesoderm.</p> Signup and view all the answers

    What is primarily formed by the cytotrophoblast during the second week?

    <p>Primary villi.</p> Signup and view all the answers

    What process occurs to create a primitive uteroplacental circulation during the second week of development?

    <p>Entry of maternal blood into lacunae.</p> Signup and view all the answers

    What is the function of amnioblasts that arise from the epiblast?

    <p>To contribute to the formation of the amniotic cavity.</p> Signup and view all the answers

    What is a consequence of the embryo being completely embedded by the end of the second week?

    <p>The mucosal surface defect has healed.</p> Signup and view all the answers

    How do epiblast and hypoblast contribute to the structure of the blastocyst?

    <p>They create a bilaminar disc that organizes further development.</p> Signup and view all the answers

    Which structure is formed from the cranial part of the embryo during head fold development?

    <p>Foregut</p> Signup and view all the answers

    What does the term 'vitellointestinal duct' refer to in the context of lateral folding?

    <p>The constricted communication between the extraembryonic coelom and midgut</p> Signup and view all the answers

    During the head fold process, which structure is positioned ventrally to the embryo after folding?

    <p>Oral membrane</p> Signup and view all the answers

    What structure is formed from the terminal part of the hind gut during development?

    <p>Cloaca</p> Signup and view all the answers

    What is the primary result of cephalocaudal folding on the embryo?

    <p>Creation of a cylindrical embryo shape</p> Signup and view all the answers

    Which of the following structures is located at the caudal part of the embryo before folding?

    <p>Cloacal membrane</p> Signup and view all the answers

    What happens to the allantois during the tail fold process?

    <p>It moves to a ventral position relative to the embryo</p> Signup and view all the answers

    Which embryonic structure develops from the area around the buccopharyngeal membrane?

    <p>Heart</p> Signup and view all the answers

    What triggers the lateral folding of the embryo?

    <p>Rapid growth of the somites</p> Signup and view all the answers

    Which embryonic cavity increases in size at the expense of the extraembryonic coelom during lateral folding?

    <p>Amniotic cavity</p> Signup and view all the answers

    Which decidua serves as the maternal origin of the placenta?

    <p>Decidua basalis</p> Signup and view all the answers

    What is the role of the syncytiotrophoblast during early pregnancy?

    <p>To produce human chorionic gonadotropin (hCG)</p> Signup and view all the answers

    Where is an ectopic pregnancy most commonly located?

    <p>In the fallopian tube</p> Signup and view all the answers

    What ultimately happens to the decidua capsularis, parietalis, and marginalis during pregnancy?

    <p>They fuse and degenerate as pregnancy progresses</p> Signup and view all the answers

    What is a potential result of abnormal implantation in the uterus?

    <p>Early miscarriage or severe internal hemorrhage</p> Signup and view all the answers

    What primarily characterizes the syncytiotrophoblast during the second week of development?

    <p>It initiates the erosion of maternal tissues to establish circulatory connections.</p> Signup and view all the answers

    What is the primary significance of the primitive uteroplacental circulation established by the end of the second week?

    <p>It facilitates the exchange of nutrients and waste products between maternal blood and the developing embryo.</p> Signup and view all the answers

    Which cells contribute to the formation of the bilaminar disc during the second week of development?

    <p>Epiblast and hypoblast.</p> Signup and view all the answers

    What is the expected result of the blastocyst being completely embedded by the end of the second week?

    <p>Healing of the surface defect in the uterine mucosa.</p> Signup and view all the answers

    What primary role does the extraembryonic mesoderm play during the second week of development?

    <p>It serves as a foundational layer for the chorionic cavity.</p> Signup and view all the answers

    What is the primary role of the notochord during embryonic development?

    <p>It serves as a template for the axial skeleton.</p> Signup and view all the answers

    Which cell layer contributes to the formation of the definitive endoderm during gastrulation?

    <p>Epiblastic cells</p> Signup and view all the answers

    What structure is formed from the primitive pit during gastrulation?

    <p>Notochord</p> Signup and view all the answers

    Which statement accurately describes the formation of the intraembryonic mesoderm?

    <p>It is created from invaginating epiblastic cells during gastrulation.</p> Signup and view all the answers

    What is the significance of the area of the oral membrane during the formation of the germ layers?

    <p>It remains unseparated between the ectoderm and endoderm.</p> Signup and view all the answers

    What is the primary role of anchoring villi in placental development?

    <p>Anchoring the placenta to the uterine wall</p> Signup and view all the answers

    Which of the following factors is implicated in the development of preeclampsia?

    <p>Inadequate invasion of trophoblast cells into the decidua</p> Signup and view all the answers

    What is the primary source of amniotic fluid during the first trimester of pregnancy?

    <p>Maternal blood and secretion by amnioblasts</p> Signup and view all the answers

    Which function is NOT associated with the amniotic fluid surrounding the embryo?

    <p>Providing oxygen supply</p> Signup and view all the answers

    What is the composition of amniotic fluid at the end of pregnancy?

    <p>98% water with 2% salts, enzymes, and hormones</p> Signup and view all the answers

    Study Notes

    Fertilization, Cleavage & Implantation

    • Fertilization is the process of a mature sperm and ovum fusing to form a zygote
    • Fertilization occurs in the ampullary part of the uterine tube
    • Spermatozoa require capacitation and acrosome reaction prior to fertilization
    • Spermatozoa consists of a head, neck, middle piece, and tail
    • The head houses the nucleus and acrosome
    • The middle piece contains mitochondria for energy
    • The tail (flagellum) is responsible for motility
    • The acrosome contains enzymes to penetrate the zona pellucida

    Stages of fertilization

    • Phase 1: Sperm penetrates the corona radiata
    • Phase 2: Sperm penetrates the zona pellucida
    • Phase 3: Fusion of sperm and egg cell membranes

    Results of fertilization

    • Restoration of diploid chromosome number
    • Determination of the sex of the zygote
    • Initiation of cleavage

    Cleavage

    • A series of mitotic divisions increasing the number of cells
    • Occurs in the uterine tube, medial to the ampulla
    • Morula stage is an early stage of cleavage

    Blastocyst Formation

    • Fluid from the uterine cavity penetrates the zona pellucida forming a blastocele
    • Blastomeres are divided into inner cell mass and outer cells
    • The inner cell mass forms the embryo proper
    • The outer cells form the trophoblast

    Implantation

    • Penetration of the blastocyst into the uterine endometrium
    • Occurs around the 6th to 11th day post-fertilization.
    • Normal implantation sites are in the anterior or posterior wall of the uterine body
    • Implantation involves the trophoblast proliferating and differentiating into cytotrophoblast and syncytiotrophoblast
    • The syncytiotrophoblast erodes maternal tissues enabling the blastocyst to burrow and implant

    The Decidua

    • The endometrium after implantation
    • Decidua basalis: part of the endometrium lying between the blastocyst and myometrium, forming the maternal part of the placenta
    • Decidua capsularis: part of the endometrium covering the implanted blastocyst, lying between the blastocyst and uterine cavity
    • Decidua parietalis: part of the endometrium lining the rest of the uterine cavity
    • Decidua marginalis: part of the endometrium lying at the junction of decidua capsularis and parietalis

    Clinical Correlates

    • Abnormal implantation (ectopic pregnancy): implantation outside the uterus
    • Placenta previa: implantation of the blastocyst in the lower segment of the uterus close to the internal os
    • Hydatidiform mole: abnormal placental development
    • Preeclampsia: Insufficient invasion of trophoblast cells into spiral arteries

    The Embryonic Period

    • The period of organogenesis (3-8 weeks)
    • The flat trilaminar embryonic disc becomes a cylindrical embryo through folding
    • The epiblast and hypoblast form layers of the embryonic disc
    • Processes like gastrulation and neurulation occur resulting in the formation of the three germ layers

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    Description

    This quiz covers the essential processes of fertilization, cleavage, and implantation in human development. Explore the phases of fertilization, the roles of sperm structures, and the initial stages of cell division after fertilization. Test your understanding of these fundamental biological concepts.

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