Questions and Answers
What is the brand name of Fenofibrate?
What is the drug class of Fenofibrate?
antihyperlipidemic, fibric acid
Name one other drug in the same drug class as Fenofibrate.
gemfibrozil
Which of the following dosage forms are available for Fenofibrate? (Select all that apply)
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What are some FDA labeled indications for Fenofibrate? (Select all that apply)
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What is a common adverse side effect of Fenofibrate?
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What is a serious adverse side effect associated with Fenofibrate?
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Fenofibrate may cause ______ as a gastrointestinal side effect.
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What should a patient report when taking Fenofibrate?
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Fenofibrate should be taken with food.
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Study Notes
Brand Name
- Fenofibrate is marketed under the brand name Tricor.
Drug Class
- Classified as an antihyperlipidemic and a fibric acid derivative.
Other Drugs in Same Drug Class
- Similar medications include gemfibrozil, fenofibric acid, and pioglitazone.
Dosage Forms
- Available dosage forms include oral capsules at 43 mg, 50 mg, 67 mg, 130 mg, 134 mg, 150 mg, and 200 mg, as well as oral tablets at 48 mg, 54 mg, and 145 mg.
FDA Labeled Indications
- Approved for treating hypercholesterolemia, primary hypercholesterolemia of mixed dyslipidemia, hypertriglyceridemia, and hyperlipidemia as an adjunct to diet.
Common Adverse Side Effects
- Gastrointestinal issues may include abdominal pain and nausea.
- Hepatic side effects can show as elevated AST/SGOT levels and abnormal liver function tests.
- Musculoskeletal complaints may manifest as backache.
- Respiratory side effects include rhinitis.
Serious Adverse Side Effects
- Potential serious gastrointestinal side effect: pancreatitis.
- Hepatic condition: cholestatic hepatitis.
- Serious musculoskeletal reaction: rhabdomyolysis.
- Renal concern: elevated serum creatinine levels.
Clinical Teaching
- Patients may experience abdominal pain, diarrhea, constipation, nausea, or rhinitis as common side effects.
- Important to report symptoms of myopathy, hepatitis, or pancreatitis immediately.
- Should be taken 1 hour before or 4-6 hours after a bile acid binding resin.
- Available under multiple brand names, which may have differing properties (consult information for specifics).
- Caution advised with coumarin anticoagulants to avoid interactions.
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Description
Test your knowledge of Fenofibrate with these flashcards. Each card covers essential information including brand names, drug class, other drugs in the same class, dosage forms, and FDA labeled indications. Perfect for students in pharmacology or healthcare fields.
