Female Reproductive System
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Questions and Answers

What is the main function of the basal layer of the endometrium?

  • To produce glycogen and other nutrients
  • To house the deep basal ends of the uterine glands (correct)
  • To regenerate the functional layer
  • To undergo profound changes during menstruation
  • During the proliferative phase, what drives the rapid cell proliferation?

  • Rising progesterone levels
  • Decreasing progesterone levels
  • Rising estrogen levels (correct)
  • Decreasing estrogen levels
  • What is the outcome of the proliferative phase?

  • The endometrium sheds during menstruation
  • The endometrium prepares for the subsequent secretory phase (correct)
  • The endometrium becomes more glandular and vascularized
  • The endometrium becomes less glandular and vascularized
  • During the secretory phase, what is produced by the uterine glands?

    <p>Glycogen and other nutrients</p> Signup and view all the answers

    What is the duration of the secretory phase?

    <p>14 days</p> Signup and view all the answers

    What is the function of the cervical mucus during ovulation?

    <p>To facilitate sperm movement to the uterus</p> Signup and view all the answers

    What is the transformation zone?

    <p>The area where the simple columnar epithelium changes to stratified squamous epithelium</p> Signup and view all the answers

    What happens to the cervix during pregnancy?

    <p>It becomes more rigid</p> Signup and view all the answers

    What is cervical effacement?

    <p>The process of the cervix softening before childbirth</p> Signup and view all the answers

    What helps to remove collagen during cervical effacement?

    <p>Macrophages</p> Signup and view all the answers

    What is the composition of the stroma in the basal layer of the endometrium?

    <p>Highly cellular stroma</p> Signup and view all the answers

    What is the result of the endometrial growth during the proliferative phase?

    <p>Regeneration of the functional layer</p> Signup and view all the answers

    What is the characteristic of the glands in the secretory phase?

    <p>Coiled and dilated</p> Signup and view all the answers

    What is the purpose of the cervical mucus during ovulation?

    <p>To facilitate sperm movement</p> Signup and view all the answers

    What happens to the cervix during pregnancy?

    <p>It becomes more rigid</p> Signup and view all the answers

    What is the primary component of the cervix?

    <p>Dense connective tissue</p> Signup and view all the answers

    What is the purpose of the cervical glands?

    <p>To secrete mucus</p> Signup and view all the answers

    What is the result of the removal of collagen during cervical effacement?

    <p>Softening of the cervix</p> Signup and view all the answers

    What is the function of macrophages during cervical effacement?

    <p>To remove collagen</p> Signup and view all the answers

    What is the outcome of cervical effacement?

    <p>The cervix dilates</p> Signup and view all the answers

    What is the main characteristic of the functional layer of the endometrium?

    <p>It is rich in ground substance</p> Signup and view all the answers

    During which phase does the endometrium thicken?

    <p>Proliferative phase</p> Signup and view all the answers

    What is the outcome of the secretory phase?

    <p>Preparation for implantation</p> Signup and view all the answers

    What type of epithelium covers the external os?

    <p>Nonkeratinized stratified squamous epithelium</p> Signup and view all the answers

    What is the primary function of the cervical glands?

    <p>Producing mucus to facilitate sperm movement</p> Signup and view all the answers

    What occurs to the cervix during pregnancy?

    <p>It becomes more rigid to retain the fetus</p> Signup and view all the answers

    What is the result of collagen removal during cervical effacement?

    <p>The cervix becomes softer</p> Signup and view all the answers

    During which phase is the uterine gland morphology altered?

    <p>Secretory phase</p> Signup and view all the answers

    What is the characteristic of the stroma in the basal layer of the endometrium?

    <p>Highly cellular</p> Signup and view all the answers

    What is the function of macrophages during cervical effacement?

    <p>Removing collagen</p> Signup and view all the answers

    What is the function of the tunica albuginea in the ovary?

    <p>To protect the ovary from damage</p> Signup and view all the answers

    What is the function of the germinal epithelium in the ovary?

    <p>To cover the surface of the ovary</p> Signup and view all the answers

    What is the ovarian medulla composed of?

    <p>Loose connective tissue and blood vessels</p> Signup and view all the answers

    What is the function of the ovarian follicles?

    <p>To hold and transport oocytes</p> Signup and view all the answers

    What is the basal lamina in an ovarian follicle?

    <p>A thin layer that separates the follicle from surrounding tissue</p> Signup and view all the answers

    What is the structure of an ovarian follicle?

    <p>An oocyte surrounded by one or more layers of epithelial cells within a basal lamina</p> Signup and view all the answers

    What happens to the follicle that does not become dominant during a menstrual cycle?

    <p>It undergoes atresia</p> Signup and view all the answers

    What is the purpose of the zona pellucida?

    <p>To facilitate communication between the oocyte and granulosa cells</p> Signup and view all the answers

    What is the purpose of inhibin in the menstrual cycle?

    <p>To reinforce the negative feedback of estrogen and progesterone</p> Signup and view all the answers

    What is the function of the theca interna?

    <p>To secrete androstenedione</p> Signup and view all the answers

    What is the fate of the corpus luteum in the absence of pregnancy?

    <p>It undergoes apoptosis and is replaced by the corpus albicans</p> Signup and view all the answers

    What is the function of the LH surge during ovulation?

    <p>To complete meiosis I and induce ovulation</p> Signup and view all the answers

    What is the main difference between a unilaminar primary follicle and a multilaminar primary follicle?

    <p>The number of layers of granulosa cells</p> Signup and view all the answers

    What is the main component of follicular fluid?

    <p>Hyaluronic acid and growth factors</p> Signup and view all the answers

    What is the role of macrophages in atresia?

    <p>To phagocytose the apoptotic material and debris</p> Signup and view all the answers

    What is the role of aromatase in granulosa cells?

    <p>Conversion of androstenedione to estrogen</p> Signup and view all the answers

    What is the fate of the oocyte if it is not fertilized within 24 hours after ovulation?

    <p>It begins to degenerate</p> Signup and view all the answers

    What is the characteristic of the oocyte in primordial follicles?

    <p>Large nucleus with chromosomes in prophase I</p> Signup and view all the answers

    What is the primary function of granulosa lutein cells?

    <p>To produce estrogen and progesterone</p> Signup and view all the answers

    What is the purpose of the corpus luteum of menstruation?

    <p>To produce estrogen and progesterone for 10-12 days</p> Signup and view all the answers

    What is the function of the ciliated cells in the epithelium of the ovioduct?

    <p>To promote movement of the oocyte into the infundibilum</p> Signup and view all the answers

    During pregnancy, what happens to the smooth muscle fibers in the myometrium?

    <p>They increase in number and size</p> Signup and view all the answers

    What is the innermost layer of the uterine wall?

    <p>Endometrium</p> Signup and view all the answers

    What is the purpose of the secretions from the peg cells in the ovioduct?

    <p>To nourish and protect the oocyte and sperm</p> Signup and view all the answers

    What is the primary difference between the basal layer and the functional layer of the endometrium?

    <p>Composition of the stroma</p> Signup and view all the answers

    What is the primary purpose of the spiral arteries during the proliferative phase?

    <p>To increase blood flow to the functional layer</p> Signup and view all the answers

    What is the result of increased estrogen levels during the proliferative phase?

    <p>Rapid cell proliferation and endometrial growth</p> Signup and view all the answers

    What is the primary function of the cervical glands?

    <p>To produce mucus that facilitates sperm movement</p> Signup and view all the answers

    What is the result of the removal of collagen during cervical effacement?

    <p>Softening of the cervix</p> Signup and view all the answers

    What is the characteristic of the exocervical mucosa?

    <p>Nonkeratinized stratified squamous epithelium</p> Signup and view all the answers

    Study Notes

    Components of the Female Reproductive System

    • Ovaries: paired organs, two on each side of the uterus, responsible for producing oocytes
    • Fallopian tubes/oviducts: two tubes, each connecting an ovary to the uterus, providing a site for fertilization
    • Uterus: muscle organ located in the pelvic cavity, holds and supports the fetus during development
    • Vagina: muscular canal connecting the cervix of the uterus to the external genitalia
    • External genitalia: labia majora, labia minora, clitoris, and vaginal opening

    Functions of the Female Reproductive System

    • Production of female gametes: ovaries produce oocytes
    • Fertilization environment: oviducts transport oocytes from the ovaries to the uterus and provide a site for fertilization
    • Support for embryo: uterus holds and supports the fetus throughout development
    • Hormone production: ovaries produce hormones that control the reproductive system and influence other organs

    Ovarian Structure

    • Surface of the ovaries: covered by simple cuboidal epithelium called germinal epithelium
    • Beneath the epithelium: dense layer of connective tissue (CT) called tunica albuginea
    • Cortex: region with stroma of highly cellular CT and many ovarian follicles
    • Medulla: internal part of the ovary, containing loose CT and blood vessels entering the organ from the hilum

    Ovarian Follicle Structure

    • An ovarian follicle consists of an oocyte surrounded by one or more layers of epithelial cells within a basal lamina
    • Basal lamina: a thin layer that separates the follicle from surrounding tissue
    • Primordial follicles: formed during fetal life, consisting of a primary oocyte enveloped by a single layer of flattened follicular cells
    • Oocyte in primordial follicles: has a large nucleus containing chromosomes in the first meiotic prophase, numerous mitochondria, and extensive rough endoplasmic reticulum

    Follicular Growth and Development

    • Involves the growth of the oocyte, proliferation and changes in the cells surrounding the oocyte, and proliferation and differentiation of the stroma fibroblasts
    • Selection of primordial follicles that will undergo growth and which follicle will ovulate involves complex hormonal balances and subtle differences among follicles

    Atresia

    • Involves programmed cell death
    • During each menstrual cycle, one follicle becomes dominant and continues to grow, while others undergo atresia
    • Stages of atresia: granulosa cells detach, oocyte undergoes self-digestion, zona pellucida collapses, and macrophages invade the degenerating follicle to phagocytose apoptotic material and debris

    Ovulation

    • Process where an oocyte is released from the ovary
    • Pre-ovulation: the dominant follicle grows and budges at the outer layer of the ovary, a translucent area called the stigma appears
    • Just before ovulation: the oocyte completes its first meiotic division, which it had started and paused during fetal development
    • At ovulation: the secondary oocyte begins the second division, but stops at metaphase, only completing it if fertilized

    Hormonal Regulation

    • Follicular development depends on follicle-stimulating hormone (FSH) from the pituitary gland, which is stimulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus
    • Estrogen and feedback mechanism: the dominant follicle secretes estrogen, which increases the release of GnRH and leads to a surge in luteinizing hormone (LH) from the pituitary gland
    • Inhibin: a hormone produced by granulosa and luteal cells that reinforces the negative feedback of estrogen and progesterone on the hypothalamus and anterior pituitary

    Components of the Female Reproductive System

    • Ovaries: paired organs, two on each side of the uterus, responsible for producing oocytes
    • Fallopian tubes/oviducts: two tubes, each connecting an ovary to the uterus, providing a site for fertilization
    • Uterus: muscle organ located in the pelvic cavity, holds and supports the fetus during development
    • Vagina: muscular canal connecting the cervix of the uterus to the external genitalia
    • External genitalia: labia majora, labia minora, clitoris, and vaginal opening

    Functions of the Female Reproductive System

    • Production of female gametes: ovaries produce oocytes
    • Fertilization environment: oviducts transport oocytes from the ovaries to the uterus and provide a site for fertilization
    • Support for embryo: uterus holds and supports the fetus throughout development
    • Hormone production: ovaries produce hormones that control the reproductive system and influence other organs

    Ovarian Structure

    • Surface of the ovaries: covered by simple cuboidal epithelium called germinal epithelium
    • Beneath the epithelium: dense layer of connective tissue (CT) called tunica albuginea
    • Cortex: region with stroma of highly cellular CT and many ovarian follicles
    • Medulla: internal part of the ovary, containing loose CT and blood vessels entering the organ from the hilum

    Ovarian Follicle Structure

    • An ovarian follicle consists of an oocyte surrounded by one or more layers of epithelial cells within a basal lamina
    • Basal lamina: a thin layer that separates the follicle from surrounding tissue
    • Primordial follicles: formed during fetal life, consisting of a primary oocyte enveloped by a single layer of flattened follicular cells
    • Oocyte in primordial follicles: has a large nucleus containing chromosomes in the first meiotic prophase, numerous mitochondria, and extensive rough endoplasmic reticulum

    Follicular Growth and Development

    • Involves the growth of the oocyte, proliferation and changes in the cells surrounding the oocyte, and proliferation and differentiation of the stroma fibroblasts
    • Selection of primordial follicles that will undergo growth and which follicle will ovulate involves complex hormonal balances and subtle differences among follicles

    Atresia

    • Involves programmed cell death
    • During each menstrual cycle, one follicle becomes dominant and continues to grow, while others undergo atresia
    • Stages of atresia: granulosa cells detach, oocyte undergoes self-digestion, zona pellucida collapses, and macrophages invade the degenerating follicle to phagocytose apoptotic material and debris

    Ovulation

    • Process where an oocyte is released from the ovary
    • Pre-ovulation: the dominant follicle grows and budges at the outer layer of the ovary, a translucent area called the stigma appears
    • Just before ovulation: the oocyte completes its first meiotic division, which it had started and paused during fetal development
    • At ovulation: the secondary oocyte begins the second division, but stops at metaphase, only completing it if fertilized

    Hormonal Regulation

    • Follicular development depends on follicle-stimulating hormone (FSH) from the pituitary gland, which is stimulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus
    • Estrogen and feedback mechanism: the dominant follicle secretes estrogen, which increases the release of GnRH and leads to a surge in luteinizing hormone (LH) from the pituitary gland
    • Inhibin: a hormone produced by granulosa and luteal cells that reinforces the negative feedback of estrogen and progesterone on the hypothalamus and anterior pituitary

    Components of the Female Reproductive System

    • Ovaries: paired organs, two on each side of the uterus, responsible for producing oocytes
    • Fallopian tubes/oviducts: two tubes, each connecting an ovary to the uterus, providing a site for fertilization
    • Uterus: muscle organ located in the pelvic cavity, holds and supports the fetus during development
    • Vagina: muscular canal connecting the cervix of the uterus to the external genitalia
    • External genitalia: labia majora, labia minora, clitoris, and vaginal opening

    Functions of the Female Reproductive System

    • Production of female gametes: ovaries produce oocytes
    • Fertilization environment: oviducts transport oocytes from the ovaries to the uterus and provide a site for fertilization
    • Support for embryo: uterus holds and supports the fetus throughout development
    • Hormone production: ovaries produce hormones that control the reproductive system and influence other organs

    Ovarian Structure

    • Surface of the ovaries: covered by simple cuboidal epithelium called germinal epithelium
    • Beneath the epithelium: dense layer of connective tissue (CT) called tunica albuginea
    • Cortex: region with stroma of highly cellular CT and many ovarian follicles
    • Medulla: internal part of the ovary, containing loose CT and blood vessels entering the organ from the hilum

    Ovarian Follicle Structure

    • An ovarian follicle consists of an oocyte surrounded by one or more layers of epithelial cells within a basal lamina
    • Basal lamina: a thin layer that separates the follicle from surrounding tissue
    • Primordial follicles: formed during fetal life, consisting of a primary oocyte enveloped by a single layer of flattened follicular cells
    • Oocyte in primordial follicles: has a large nucleus containing chromosomes in the first meiotic prophase, numerous mitochondria, and extensive rough endoplasmic reticulum

    Follicular Growth and Development

    • Involves the growth of the oocyte, proliferation and changes in the cells surrounding the oocyte, and proliferation and differentiation of the stroma fibroblasts
    • Selection of primordial follicles that will undergo growth and which follicle will ovulate involves complex hormonal balances and subtle differences among follicles

    Atresia

    • Involves programmed cell death
    • During each menstrual cycle, one follicle becomes dominant and continues to grow, while others undergo atresia
    • Stages of atresia: granulosa cells detach, oocyte undergoes self-digestion, zona pellucida collapses, and macrophages invade the degenerating follicle to phagocytose apoptotic material and debris

    Ovulation

    • Process where an oocyte is released from the ovary
    • Pre-ovulation: the dominant follicle grows and budges at the outer layer of the ovary, a translucent area called the stigma appears
    • Just before ovulation: the oocyte completes its first meiotic division, which it had started and paused during fetal development
    • At ovulation: the secondary oocyte begins the second division, but stops at metaphase, only completing it if fertilized

    Hormonal Regulation

    • Follicular development depends on follicle-stimulating hormone (FSH) from the pituitary gland, which is stimulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus
    • Estrogen and feedback mechanism: the dominant follicle secretes estrogen, which increases the release of GnRH and leads to a surge in luteinizing hormone (LH) from the pituitary gland
    • Inhibin: a hormone produced by granulosa and luteal cells that reinforces the negative feedback of estrogen and progesterone on the hypothalamus and anterior pituitary

    Components of the Female Reproductive System

    • Ovaries: paired organs, two on each side of the uterus, responsible for producing oocytes
    • Fallopian tubes/oviducts: two tubes, each connecting an ovary to the uterus, providing a site for fertilization
    • Uterus: muscle organ located in the pelvic cavity, holds and supports the fetus during development
    • Vagina: muscular canal connecting the cervix of the uterus to the external genitalia
    • External genitalia: labia majora, labia minora, clitoris, and vaginal opening

    Functions of the Female Reproductive System

    • Production of female gametes: ovaries produce oocytes
    • Fertilization environment: oviducts transport oocytes from the ovaries to the uterus and provide a site for fertilization
    • Support for embryo: uterus holds and supports the fetus throughout development
    • Hormone production: ovaries produce hormones that control the reproductive system and influence other organs

    Ovarian Structure

    • Surface of the ovaries: covered by simple cuboidal epithelium called germinal epithelium
    • Beneath the epithelium: dense layer of connective tissue (CT) called tunica albuginea
    • Cortex: region with stroma of highly cellular CT and many ovarian follicles
    • Medulla: internal part of the ovary, containing loose CT and blood vessels entering the organ from the hilum

    Ovarian Follicle Structure

    • An ovarian follicle consists of an oocyte surrounded by one or more layers of epithelial cells within a basal lamina
    • Basal lamina: a thin layer that separates the follicle from surrounding tissue
    • Primordial follicles: formed during fetal life, consisting of a primary oocyte enveloped by a single layer of flattened follicular cells
    • Oocyte in primordial follicles: has a large nucleus containing chromosomes in the first meiotic prophase, numerous mitochondria, and extensive rough endoplasmic reticulum

    Follicular Growth and Development

    • Involves the growth of the oocyte, proliferation and changes in the cells surrounding the oocyte, and proliferation and differentiation of the stroma fibroblasts
    • Selection of primordial follicles that will undergo growth and which follicle will ovulate involves complex hormonal balances and subtle differences among follicles

    Atresia

    • Involves programmed cell death
    • During each menstrual cycle, one follicle becomes dominant and continues to grow, while others undergo atresia
    • Stages of atresia: granulosa cells detach, oocyte undergoes self-digestion, zona pellucida collapses, and macrophages invade the degenerating follicle to phagocytose apoptotic material and debris

    Ovulation

    • Process where an oocyte is released from the ovary
    • Pre-ovulation: the dominant follicle grows and budges at the outer layer of the ovary, a translucent area called the stigma appears
    • Just before ovulation: the oocyte completes its first meiotic division, which it had started and paused during fetal development
    • At ovulation: the secondary oocyte begins the second division, but stops at metaphase, only completing it if fertilized

    Hormonal Regulation

    • Follicular development depends on follicle-stimulating hormone (FSH) from the pituitary gland, which is stimulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus
    • Estrogen and feedback mechanism: the dominant follicle secretes estrogen, which increases the release of GnRH and leads to a surge in luteinizing hormone (LH) from the pituitary gland
    • Inhibin: a hormone produced by granulosa and luteal cells that reinforces the negative feedback of estrogen and progesterone on the hypothalamus and anterior pituitary

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    Description

    This quiz covers the components and functions of the female reproductive system, including the ovaries, fallopian tubes, uterus, vagina, and external genitalia.

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