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Questions and Answers
What is a common cause of upper respiratory tract disease in cats?
What is a common cause of upper respiratory tract disease in cats?
Which clinical sign is NOT typically associated with feline upper respiratory tract infections?
Which clinical sign is NOT typically associated with feline upper respiratory tract infections?
Which factor is important in constructing a differential diagnosis list for respiratory diseases?
Which factor is important in constructing a differential diagnosis list for respiratory diseases?
What are some of the common clinical signs of upper respiratory tract disease in cats?
What are some of the common clinical signs of upper respiratory tract disease in cats?
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What should be included when assessing a patient's history for respiratory diseases?
What should be included when assessing a patient's history for respiratory diseases?
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Which of the following is a potential complication of feline calicivirus infections?
Which of the following is a potential complication of feline calicivirus infections?
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What could be a potential welfare implication of treating respiratory diseases in pets?
What could be a potential welfare implication of treating respiratory diseases in pets?
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What is a common clinical sign associated with chronic rhinitis in cats?
What is a common clinical sign associated with chronic rhinitis in cats?
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What anatomical feature is commonly affected in Brachycephalic Obstructive Airway Syndrome?
What anatomical feature is commonly affected in Brachycephalic Obstructive Airway Syndrome?
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Which breed is NOT commonly associated with Brachycephalic Obstructive Airway Syndrome?
Which breed is NOT commonly associated with Brachycephalic Obstructive Airway Syndrome?
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Which clinical sign is associated with laryngeal paralysis?
Which clinical sign is associated with laryngeal paralysis?
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What is a common treatment method for Brachycephalic Obstructive Airway Syndrome?
What is a common treatment method for Brachycephalic Obstructive Airway Syndrome?
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Which of the following is a potential cause of acquired laryngeal paralysis?
Which of the following is a potential cause of acquired laryngeal paralysis?
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Which is NOT a clinical sign of Brachycephalic Obstructive Airway Syndrome?
Which is NOT a clinical sign of Brachycephalic Obstructive Airway Syndrome?
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What medical imaging technique is used to assess tracheal and nasal anatomy in dogs with suspected airway disease?
What medical imaging technique is used to assess tracheal and nasal anatomy in dogs with suspected airway disease?
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Which of the following clinical signs indicates a severe case of laryngeal paralysis?
Which of the following clinical signs indicates a severe case of laryngeal paralysis?
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What is a key diagnostic method for feline upper respiratory tract infections?
What is a key diagnostic method for feline upper respiratory tract infections?
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Which of the following is a recommended treatment for feline upper respiratory tract infections?
Which of the following is a recommended treatment for feline upper respiratory tract infections?
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Chronic rhinosinusitis in cats is often secondary to which viral infections?
Chronic rhinosinusitis in cats is often secondary to which viral infections?
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What clinical sign is commonly associated with chronic rhinosinusitis in cats?
What clinical sign is commonly associated with chronic rhinosinusitis in cats?
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How long may treatment with broad-spectrum antibiotics be necessary for chronic rhinosinusitis?
How long may treatment with broad-spectrum antibiotics be necessary for chronic rhinosinusitis?
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Which of the following is NOT a recommended prevention method for feline upper respiratory infections?
Which of the following is NOT a recommended prevention method for feline upper respiratory infections?
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What approach is taken for the treatment of allergic rhinitis in cats?
What approach is taken for the treatment of allergic rhinitis in cats?
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What is a common treatment to ease respiratory congestion in cats?
What is a common treatment to ease respiratory congestion in cats?
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Which of the following is NOT a common cause of allergic rhinitis in cats?
Which of the following is NOT a common cause of allergic rhinitis in cats?
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What type of nasal discharge is usually associated with allergic rhinitis in cats?
What type of nasal discharge is usually associated with allergic rhinitis in cats?
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What can support a diagnosis of allergic rhinitis in cats?
What can support a diagnosis of allergic rhinitis in cats?
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Which symptom is a possible sign of severe allergic rhinitis in cats that may lead to a diagnosis of allergic bronchitis or asthma?
Which symptom is a possible sign of severe allergic rhinitis in cats that may lead to a diagnosis of allergic bronchitis or asthma?
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What treatment method is typically used to manage allergic rhinitis in cats?
What treatment method is typically used to manage allergic rhinitis in cats?
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Which clinical sign indicates that a foreign body may be lodged in the nasopharynx of a cat?
Which clinical sign indicates that a foreign body may be lodged in the nasopharynx of a cat?
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What should be monitored during the treatment of allergic rhinitis in cats receiving corticosteroids?
What should be monitored during the treatment of allergic rhinitis in cats receiving corticosteroids?
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Which of the following indicates a secondary bacterial infection due to an irritant in a cat's nasal passage?
Which of the following indicates a secondary bacterial infection due to an irritant in a cat's nasal passage?
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What is a primary characteristic of leukocytosis observed in haematology?
What is a primary characteristic of leukocytosis observed in haematology?
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Which of the following is a common clinical sign of lungworm infection in cats?
Which of the following is a common clinical sign of lungworm infection in cats?
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What is the recommended treatment for lungworm in cats?
What is the recommended treatment for lungworm in cats?
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Which diagnostic method is most effective for confirming lungworm infection?
Which diagnostic method is most effective for confirming lungworm infection?
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What is a typical clinical sign of infectious tracheobronchitis in dogs?
What is a typical clinical sign of infectious tracheobronchitis in dogs?
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What is the first-line treatment for kennel cough in dogs?
What is the first-line treatment for kennel cough in dogs?
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What should be done to manage a dog diagnosed with kennel cough?
What should be done to manage a dog diagnosed with kennel cough?
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What procedure is often necessary to diagnose nasopharyngeal foreign bodies?
What procedure is often necessary to diagnose nasopharyngeal foreign bodies?
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In the treatment of kennel cough, when should antibiotics be considered?
In the treatment of kennel cough, when should antibiotics be considered?
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What are common clinical signs of nasopharyngeal polyps in cats?
What are common clinical signs of nasopharyngeal polyps in cats?
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Which of the following treatments is recommended for nasopharyngeal polyps?
Which of the following treatments is recommended for nasopharyngeal polyps?
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What is the possible cause of nasopharyngeal polyps in cats?
What is the possible cause of nasopharyngeal polyps in cats?
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Which symptoms are associated with fungal rhinitis in cats?
Which symptoms are associated with fungal rhinitis in cats?
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Which type of imaging is typically used for diagnosing nasopharyngeal polyps?
Which type of imaging is typically used for diagnosing nasopharyngeal polyps?
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After surgical removal of a nasopharyngeal polyp, what is a common post-operative outcome?
After surgical removal of a nasopharyngeal polyp, what is a common post-operative outcome?
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Which species is known to sometimes cause fungal rhinitis in cats?
Which species is known to sometimes cause fungal rhinitis in cats?
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Study Notes
Respiratory Disease in Dogs, Cats, and Rabbits
- This presentation covers respiratory diseases in dogs, cats, and rabbits
- Topics include learning objectives, constructing a differential diagnosis, clinical presentation, common causes in cats and dogs, and treatment/prevention
Learning Objectives
- Construct differential diagnosis list based on clinical presentation and choose appropriate diagnostics
- Determine appropriate medical and surgical interventions in the management/treatment of airway diseases in dogs, cats, and rabbits
- Determine appropriate prognosis, and welfare implications of treatment options
- Determine control measures for disease prevention
Constructing a Differential Diagnosis: History
- Signalment (age, breed predispositions)
- When did it start?
- How did it start?
- Has it changed?
- Has it happened before?
- Vaccinations?
- Recent travel/changes in management/others affected?
- Other signs (e.g., vomiting, diarrhea)
- Any pre-existing conditions?
- Receiving medications?
- Trauma or toxin ingestion?
Constructing a Differential Diagnosis: Clinical Presentation
Upper Respiratory Tract Disease
- Sneezing
- Nasal discharge
- Stridor/stertor
- Increased inspiratory effort
- Facial deformity/pain
- Altered vocalization/loss of voice
Lower Respiratory Tract Disease
- Coughing
- Dyspnea or tachypnea
- Exercise intolerance
- Respiratory distress/cyanosis
- Other systemic signs
Common Causes of URT Disease in Cats
Feline Upper Respiratory Tract Infections
- Usually viral, common in multi-cat households/catteries
- Feline Herpesvirus (FHV-1/Feline rhinotracheitis virus) often associated with sneezing, ocular discharge, conjunctivitis, keratitis, corneal ulcers, and chronic rhinitis
- Feline Calicivirus (FCV) often associated with oral ulceration, sneezing, nasal discharge, chronic stomatitis, gingivitis, and pneumonia (severe cases)
Chronic Rhinosinusitis
- Chronic inflammatory condition, typically post-viral (secondary to FHV-1 or FCV)
- Damage to nasal turbinates reduces mucosal immunity and leads to chronic secondary infection
- Persistent or recurrent nasal discharge (mucopurulent)
- Sneezing
- Nasal obstruction
- Rule out other causes
- Radiography
- Rhinoscopy with biopsy for histopathology
- Advanced imaging (CT or MRI) for sinus assessment
Allergic Rhinitis
- Caused by allergens (e.g., pollens, dust mites, mold, cleaning agents)
- Less common than post-viral chronic rhinosinusitis
- Sneezing (often intermittent)
- Nasal discharge (typically serous/mucopurulent if secondary bacterial)
- Pawing at nose/face
- Conjunctivitis (frequently)
- Cough/wheezing (severe cases, possible allergic bronchitis/feline asthma)
Nasopharyngeal Foreign Bodies
- Commonly long grass blades lodged in nasopharynx
- Sneezing
- Unilateral nasal discharge (serous, mucopurulent, or hemorrhagic)
- Gagging, coughing, or reverse sneezing (especially if lodged in caudal nasal passages/nasopharynx)
- Pawing at face/nose
- Halitosis (secondary bacterial infection)
- Open-mouthed breathing/stridor (severe cases)
Nasopharyngeal Polyps
- Benign pedunculated growths arising from the middle ear or nasopharynx
- Chronic nasal discharge (unilateral)
- Stertor, difficulty breathing, possible dysphagia
- Otitis externa/media, vestibular signs, Horner's syndrome (if extending into middle ear)
- Visual examination (otoscopy/rhinoscopy) and imaging (radiography)
- Histopathological examination after excision
Fungal Rhinitis
- Rare in UK
- Emerging disease in cats worldwide caused by Cryptococcus, Aspergillus, and Penicillium species
- Chronic nasal discharge, epistaxis
- Stertor
- Facial swelling
- Neurological signs (seizures, blindness) if CNS involvement
- Serology (Cryptococcus spp)
- Imaging (radiography, endoscopy, turbinate lysis often seen on CT)
- Cytology and fungal plaque culture
Feline Asthma (Feline Allergic Airway Disease)
- Common lower airway inflammatory disease, allergic in origin
- Cough (inducible on tracheal palpation)
- Increased expiratory effort/wheeze
- Open-mouth breathing
- Tachypnea
- Vomiting
Common Causes of LRT Disease in Dogs
Infectious Tracheobronchitis/Canine Infectious Respiratory Disease Complex (Kennel Cough)
- High contagious viral/bacterial condition (Canine parainfluenza virus, Canine Adenovirus, Bordetella bronchiseptica)
- Harsh, hacking cough (often described as "goose honk")
- Nasal discharge
- Mild lethargy/pyrexia
- History (recent dog exposure)
- Deep oropharyngeal swab PCR test
Brachycephalic Obstructive Airway Syndrome (BOAS)
- Anatomical abnormalities in brachycephalic breeds (e.g., English/French Bulldogs, Pugs)
- Stenotic nares, aberrant/hypertrophied turbinates
- Elongated/collapse soft palate
- Narrow larynx/laryngeal hypoplasia/everted laryngeal saccules
- Hypoplastic trachea
- Skull base malformation
- Snoring/noisy breath (stertor/stridor)
- Increased respiratory effort
- Exercise intolerance
- Cyanosis/collapse
- Breed predisposition, clinical examination, endoscopic evaluation, radiographs/CT
- Surgical management (e.g., widening of narrow airways or resection)
- Weight management/avoiding stress/heat
Laryngeal Paralysis
- Paralysis of arytenoid cartilages, preventing airway opening
- Older, large-breed dogs (overrepresented in Labradors)
- Acquired form (damage to recurrent laryngeal nerve, intra- or extra-thoracic masses).
- Inspiratory stridor
- Exercise intolerance
- Coughing/dysphagia/regurgitation
- Dysphonia or change in bark
- Visual inspection (light anesthesia)
- Radiographs (masses or pneumonia)
- Neurological assessment
- Biochemistry/hematology to rule out endocrinopathies
- Surgical intervention(unilateral arytenoid lateralization)
Canine Nasal Aspergillosis
- Fungal condition, inhaled Aspergillus spores
- Dolichocephalic breeds are predisposed
- Chronic nasal discharge (serous, mucopurulent, or hemorrhagic)
- Nasal pain/discomfort
- Sneezing
- Epistaxis (nosebleeds)
- Ulceration/depigmentation of nares
- CT or radiographs (nasal turbinate destruction, tissue density increased)
- Rhinoscopy (visualizing fungal plaques in nasal cavity), cytology/culture/biopsy
- Surgical debridement of fungal plaques, topical clotrimazole instillation (every 2 weeks until negative culture/histopathology)
- Systemic antifungals (itraconazole/fluconazole; less effective than topical)
Chronic Bronchitis
- Thickening/distortion of bronchial walls, bronchiectasis, cor pulmonale
- Tracheobronchial collapse, hyperaemia, thickening/increase in mucous
- Lots of mucous, neutrophils in cytology
- Decreased oxygen saturation
- Glucocorticoids (oral/inhaled)
- Bronchodilators (e.g., theophylline)
- Nebulizers (saline/mucolytics)
Aspiration Pneumonia
- Aspiration of solid/liquid causes severe inflammatory response, alveolar damage
- Laryngeal dysfunction/megaesophagus/iatrogenic medication/vomiting
- Acute coughing/dyspnea, pyrexia/anorexia
- History, clinical signs. Radiography/ultrasound
- Supportive care (IV fluids, oxygen therapy, nutritional support)
- Antibiotics (broad spectrum with good pulmonary penetration)
Lungworm
- Parasitic infection with Angiostrongylus vasorum
- Dogs in contact with foxes, rodents that ingest snails/slugs/frogs are at high risk
- Subclinical/non-specific(lethargy, weight loss, vomiting)
- Pulmonary (cough, exercise intolerance, dyspnea)
- Coagulopathy (anemia, bleeding in the CNS)
- Cardiovascular signs (rare, possible myocarditis, heart murmurs, heart failure)
- Radiography/diffused bronchial thickening with interstitial lung pattern
- Endoscopy/variable and non-specific lung patterns/infiltrates
- Diagnostic tests like AngioDetect TM, in-house Baermann's, BAL cytology, and PCR
- Treatment with Moxidectin/imidacloprid, Milbemycin, Fenbendazole
Idiopathic Pulmonary Fibrosis
- Chronic and progressive interstitial lung disease
- Older West Highland White Terriers (WHWTs)
- Insidious onset, progression.
- Coughing
- Panting
- Respiratory distress/tachypnea
- Distinctive “Velcro crackle” on auscultation
- Cyanosis with minimal exertion
- Weakness/syncope
- Possible pulmonary hypertension
Common Causes of URT Disease in Rabbits
-
Obligate nasal breathers, URT compromise significant
-
Often termed "Snuffles", primary or secondary
-
Usually bacterial but viral and fungal causes possible
-
Dental disease, trauma, foreign bodies, neoplasia can cause URT signs
-
Pasteurella multocida – often implicated
-
Bordetella bronchiseptica, Pseudomonas species, Staphylococcus species, Moraxella catarrhalis, Mycoplasma species
-
Can be inhaled into surrounding tissues(e.g., nasolacrimal duct, conjunctivae, eustachian tubes, middle ear, inner ear, LRT)
Rabbits: Snuffles Clinical Signs
- Nasal and ocular discharge
- Snuffling, increased inspiratory respiratory rate
- Matted fur
- Dyspnea/open-mouth breathing (severe disease)
- Epiphora, conjunctivitis, dacrocystitis
- Head shaking/scratching
- Head tilt/neurological signs
- Non-specific signs (weight loss, lethargy)
Rabbits: Diagnosis
- Full nose-tail clinical examination
- Hematology and biochemistry for general health
- Deep nasal swab (bilateral)
- Sedation or local anaesthesia
- Nasolacrimal flush/biopsy of nasal mucosa
- Radiographs (dental diseases)
- Endoscopy (small bore rigid endoscope)
- CT (detailed images)
- Ultrasound (rule out cardiac disease)
Rabbits: Treatment
- Accurate diagnosis
- 14 days (longer if chronic) of treatment
- Avoid fluoroquinolones (initial line)
- Supportive care (fluid therapy, nutrition, NSAIDs)
- Treatment failures = consider inaccurate diagnosis/different type of bacterial disease (e.g., abscesses/granulomas)
- Severe cases = surgery (rhinotomy/rhinostomy), flushing, and topical antibiotics
Rabbits: Lower Respiratory Disease
- No septa dividing lungs = generalized lung disease
- Respiration mainly diaphragmatic = increased intra-abdominal pressure
- Same infectious agents as URT
- Mycoplasma species and Chlamydophila species isolated in pneumonia cases
- Viral/mycobacterial disease rare
- Metastatic neoplasia/cardiovascular disease/trauma
- Dyspnea, abnormal/wheezing respiratory sounds,
- Radiography/ultrasound.
- Tracheal wash/BAL for suspect LRT disease
Rabbits: Prognosis, Welfare, Prevention
- Prognosis depends on underlying cause
- Often advanced before presentation
- Snuffles= very contagious, challenging to treat, guarded prognosis
- High welfare concern
- Strict hygiene/quarantine for new rabbits important
- Isolating/barrier nursing of sick rabbits
- Excellent husbandry practices essential
Further Reading
- Various peer-reviewed articles on the given topics, available through veterinary journals/databases
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Description
Test your knowledge on common upper respiratory tract diseases in cats, including causes, clinical signs, and treatments. This quiz covers important factors for differential diagnoses and welfare implications of treating respiratory conditions in feline patients.