FDA-Approved Treatments for Postpartum Depression and Bipolar Disorders Part 1
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Questions and Answers

What is the major difference between Major Depressive Disorder (MDD) and Bipolar 2?

  • MDD and Bipolar 2 are both unipolar disorders
  • MDD involves hypomania, while Bipolar 2 is unipolar
  • MDD has more severe depressive symptoms than Bipolar 2
  • MDD is unipolar, while Bipolar 2 involves hypomania (correct)

What is the potential risk of using antidepressants without mood stabilizers for patients with bipolar depression?

  • Risk of developing schizophrenia
  • Risk of developing anxiety disorders
  • Risk of developing substance use disorders
  • Risk of switching from depression to hypomania or mania (correct)

Which Over-The-Counter (OTC) product is known for having the most potential drug interactions with CYP3A4 drugs?

  • SAMe
  • St John’s Wort (correct)
  • Fish oil
  • Melatonin

What is the therapeutic level range for lithium used in bipolar disorder treatment?

<p>0.6-1.2 mEq/L (B)</p> Signup and view all the answers

In a patient with minimal adverse drug reactions (ADRs) at 600 mg/day of lithium and a steady-state level of 0.3 mEq/L, what would be the appropriate recommendation?

<p>Increase the patient’s lithium dose by 150-300 mg per day (C)</p> Signup and view all the answers

Which Over-The-Counter (OTC) pain medications have the potential to increase lithium levels?

<p>NSAIDs like ibuprofen and naproxen (C)</p> Signup and view all the answers

What baseline labs are essential before initiating lithium treatment?

<p><strong>BUN and SCr:</strong> to assess renal function (A)</p> Signup and view all the answers

Which baseline lab test is NOT necessary before initiating lithium treatment?

<p><strong>Urine specific gravity</strong> to assess kidney function (B)</p> Signup and view all the answers

What is the recommended timing for drawing lithium levels post-dose to assess therapeutic levels?

<p>@ 10-12 hours post-dose (D)</p> Signup and view all the answers

If a patient has a steady-state lithium level of 1.5 mEq/L at a dose of 600 mg/day but experiences severe adverse effects, what would be the recommended approach?

<p>Decrease the dose by 150-300 mg/day and monitor levels closely (C)</p> Signup and view all the answers

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