FDA-Approved Treatments for Postpartum Depression and Bipolar Disorders Part 1
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Questions and Answers

What is the major difference between Major Depressive Disorder (MDD) and Bipolar 2?

  • MDD and Bipolar 2 are both unipolar disorders
  • MDD involves hypomania, while Bipolar 2 is unipolar
  • MDD has more severe depressive symptoms than Bipolar 2
  • MDD is unipolar, while Bipolar 2 involves hypomania (correct)
  • What is the potential risk of using antidepressants without mood stabilizers for patients with bipolar depression?

  • Risk of developing schizophrenia
  • Risk of developing anxiety disorders
  • Risk of developing substance use disorders
  • Risk of switching from depression to hypomania or mania (correct)
  • Which Over-The-Counter (OTC) product is known for having the most potential drug interactions with CYP3A4 drugs?

  • SAMe
  • St John’s Wort (correct)
  • Fish oil
  • Melatonin
  • What is the therapeutic level range for lithium used in bipolar disorder treatment?

    <p>0.6-1.2 mEq/L</p> Signup and view all the answers

    In a patient with minimal adverse drug reactions (ADRs) at 600 mg/day of lithium and a steady-state level of 0.3 mEq/L, what would be the appropriate recommendation?

    <p>Increase the patient’s lithium dose by 150-300 mg per day</p> Signup and view all the answers

    Which Over-The-Counter (OTC) pain medications have the potential to increase lithium levels?

    <p>NSAIDs like ibuprofen and naproxen</p> Signup and view all the answers

    What baseline labs are essential before initiating lithium treatment?

    <p><strong>BUN and SCr:</strong> to assess renal function</p> Signup and view all the answers

    Which baseline lab test is NOT necessary before initiating lithium treatment?

    <p><strong>Urine specific gravity</strong> to assess kidney function</p> Signup and view all the answers

    What is the recommended timing for drawing lithium levels post-dose to assess therapeutic levels?

    <p>@ 10-12 hours post-dose</p> Signup and view all the answers

    If a patient has a steady-state lithium level of 1.5 mEq/L at a dose of 600 mg/day but experiences severe adverse effects, what would be the recommended approach?

    <p>Decrease the dose by 150-300 mg/day and monitor levels closely</p> Signup and view all the answers

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