Lec 12-Intro to Cardio

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Questions and Answers

Which of the following is NOT a major component of the circulatory system?

  • Blood vessels
  • Kidneys (correct)
  • Heart
  • Blood

What is the purpose of having separate atrial and ventricular syncytia in the heart?

  • To regulate blood flow in the circulatory system
  • To prevent electrical impulses from spreading between the atria and ventricles (correct)
  • To maintain the electrical conduction system of the heart
  • To ensure efficient contraction of the heart

Which of the following is the only normal electrical pathway between the atria and the ventricles?

  • Bundle of His
  • Purkinje fibers
  • AV node (correct)
  • SA node

Which ion primarily determines the resting membrane potential?

<p>K+ (B)</p> Signup and view all the answers

Which channel is responsible for hyperpolarization-activated cyclic nucleotide-gated channel?

<p>HCN channel (C)</p> Signup and view all the answers

What is the role of the SA node in the heart?

<p>Generate action potentials (D)</p> Signup and view all the answers

What is the mechanism that suppresses latent pacemakers from driving the heart rate?

<p>Overdrive suppression (B)</p> Signup and view all the answers

Which component of the circulatory system carries oxygenated blood away from the heart to tissues?

<p>Arteries (D)</p> Signup and view all the answers

What is the primary function of the cardiovascular system?

<p>All of the above (D)</p> Signup and view all the answers

What is the total flow of blood out of the left ventricle known as?

<p>Cardiac output (CO) (B)</p> Signup and view all the answers

Which type of cardiac muscle cells do not contribute to the generation of force for pumping blood?

<p>Conducting cells (B)</p> Signup and view all the answers

Which type of current is responsible for repolarization in phase 3 of the action potential?

<p>Outward IK (A)</p> Signup and view all the answers

What is the main effect of sympathetic nerves on heart rate?

<p>Increase heart rate (A)</p> Signup and view all the answers

What is the effect of parasympathetic nerves on heart rate?

<p>Decrease heart rate (C)</p> Signup and view all the answers

During which phase of the action potential are most Na+ channels closed?

<p>Phase 1 (B)</p> Signup and view all the answers

Which part of the heart has the fastest conduction velocity?

<p>Purkinje fibers (B)</p> Signup and view all the answers

Which part of the heart has the slowest conduction velocity?

<p>AV node (B)</p> Signup and view all the answers

What is the purpose of the slow conduction velocity in the AV node?

<p>To prevent early activation of ventricles (D)</p> Signup and view all the answers

What is the purpose of the rapid conduction velocity in the Purkinje fibers?

<p>To ensure efficient ejection of blood (D)</p> Signup and view all the answers

Which receptor is coupled to GK that inhibits adenylyl cyclase?

<p>M2 receptors (A)</p> Signup and view all the answers

What effect does parasympathetic nerve activation have on heart rate?

<p>Decreases heart rate (A)</p> Signup and view all the answers

What causes the negative shift in the maximum diastolic potential in SA nodal cells during parasympathetic nerve activation?

<p>Increase in IK-ACh (B)</p> Signup and view all the answers

What does the PR interval on an ECG represent?

<p>Conduction time from atria to ventricles (C)</p> Signup and view all the answers

Which receptor is coupled to GK that inhibits adenylyl cyclase?

<p>M2 receptor (A)</p> Signup and view all the answers

What effect does parasympathetic nerve activation have on heart rate?

<p>Decreases heart rate (B)</p> Signup and view all the answers

What is the effect of sympathetic nervous system on conduction velocity through the AV node?

<p>Increases conduction velocity (A)</p> Signup and view all the answers

What does the PR interval on an ECG represent?

<p>Depolarization of the ventricles (D)</p> Signup and view all the answers

Which ion is responsible for the upstroke of the action potential in SA cells?

<p>Na+ (D)</p> Signup and view all the answers

What is the role of HCN channels in the SA node?

<p>To control the heart rate (D)</p> Signup and view all the answers

What is the mechanism that suppresses latent pacemakers from driving the heart rate called?

<p>Overdrive suppression (C)</p> Signup and view all the answers

Which part of the heart is responsible for generating action potentials spontaneously?

<p>SA node (B)</p> Signup and view all the answers

What is the main function of conducting cells in the heart?

<p>Carry electrical signals rapidly (D)</p> Signup and view all the answers

Which syncytium in the heart works as a coordinated unit to pump blood?

<p>Both atrial and ventricular syncytia (A)</p> Signup and view all the answers

What is the purpose of the AV node in the heart?

<p>Slow down the conduction velocity (A)</p> Signup and view all the answers

During which phase of the action potential are most Na+ channels closed?

<p>Phase 1 (C)</p> Signup and view all the answers

What is the effect of sympathetic nerves on heart rate?

<p>Increase heart rate (C)</p> Signup and view all the answers

What is the effect of parasympathetic nerves on heart rate?

<p>Decrease heart rate (A)</p> Signup and view all the answers

Which receptor is coupled to GK that inhibits adenylyl cyclase?

<p>Muscarinic M2 receptor (A)</p> Signup and view all the answers

Which part of the heart has the slowest conduction velocity?

<p>AV node (B)</p> Signup and view all the answers

What is the purpose of the slow conduction velocity in the AV node?

<p>To delay the conduction of action potential (D)</p> Signup and view all the answers

What is the purpose of having separate atrial and ventricular syncytia in the heart?

<p>To allow for smooth sequence of ventricular activation (A)</p> Signup and view all the answers

What is the effect of sympathetic nervous system on conduction velocity through the AV node?

<p>Increases conduction velocity (C)</p> Signup and view all the answers

Which of the following is true about M2 receptors?

<p>They inhibit adenylyl cyclase (B)</p> Signup and view all the answers

What effect does sympathetic nervous system have on conduction velocity through the AV node?

<p>It increases conduction velocity (D)</p> Signup and view all the answers

What does the QT interval on an ECG represent?

<p>Repolarization of the ventricles (A)</p> Signup and view all the answers

Which of the following is NOT a cause of sinus tachycardia?

<p>Parasympathetic nerve activation (D)</p> Signup and view all the answers

Which of the following is the correct sequence of cardiac activation (depolarization) starting from the SA node?

<p>SA node - AV node - bundle of His - Purkinje fibers (D)</p> Signup and view all the answers

Which of the following is responsible for lengthening the absolute refractory period in contractile cell action potentials?

<p>L-type Ca2+ (B)</p> Signup and view all the answers

What are the major features of an ECG and what do they correspond to in the heart?

<p>P wave - atrial depolarization, QRS wave - ventricular depolarization, S-T segment - ventricular repolarization, T wave - atrial repolarization (D)</p> Signup and view all the answers

Which of the following is responsible for the upstroke of the action potential in contractile cells?

<p>Na+ channels (B)</p> Signup and view all the answers

Which of the following best describes the role of the AV node in the heart?

<p>It conducts electrical signals from the atria to the ventricles. (B)</p> Signup and view all the answers

Which of the following is NOT a major component of the circulatory system?

<p>Lymph nodes (B)</p> Signup and view all the answers

Which phase of the action potential is characterized by repolarization?

<p>Phase 3 (B)</p> Signup and view all the answers

What is the effect of sympathetic nervous system on heart rate?

<p>Increases heart rate (D)</p> Signup and view all the answers

Which ion primarily determines the resting membrane potential?

<p>K+ (A)</p> Signup and view all the answers

What is the role of HCN channels in the SA node?

<p>They increase the rate of spontaneous depolarization (A)</p> Signup and view all the answers

Which of the following is responsible for generating action potentials spontaneously in the heart?

<p>Sinoatrial node (A)</p> Signup and view all the answers

Which part of the heart has the fastest conduction velocity?

<p>Sinoatrial (SA) node (B)</p> Signup and view all the answers

What is the main function of the conducting cells in the heart?

<p>To carry electrical signals rapidly (A)</p> Signup and view all the answers

What is the effect of parasympathetic nerve activation on heart rate?

<p>Decreases heart rate (D)</p> Signup and view all the answers

Which ion primarily determines the resting membrane potential?

<p>K+ (B)</p> Signup and view all the answers

What is the purpose of the slow conduction velocity in the AV node?

<p>To prevent rapid transmission of electrical signals to the ventricles (B)</p> Signup and view all the answers

What is the effect of parasympathetic nerves on heart rate?

<p>Decrease heart rate (D)</p> Signup and view all the answers

What is the role of HCN channels in the SA node?

<p>To generate action potentials (A)</p> Signup and view all the answers

Which part of the specialized conduction system has the fastest conduction velocity?

<p>Purkinje fibers (A)</p> Signup and view all the answers

What is the purpose of the slow conduction velocity in the AV node?

<p>To allow time for ventricles to fill with blood from atria (D)</p> Signup and view all the answers

What is the main function of the specialized conduction system in the heart?

<p>To coordinate the pumping of blood (A)</p> Signup and view all the answers

What is the effect of sympathetic nervous system on conduction velocity through the AV node?

<p>Increases conduction velocity (C)</p> Signup and view all the answers

Which of the following is true about M2 receptors?

<p>M2 receptors are coupled to GK that inhibits adenylyl cyclase (A)</p> Signup and view all the answers

What does the PR interval on an ECG represent?

<p>Time from initial depolarization of the atria to initial depolarization of the ventricles (B)</p> Signup and view all the answers

What effect does parasympathetic nerve activation have on heart rate?

<p>Decreases heart rate (B)</p> Signup and view all the answers

What is the purpose of the slow conduction velocity in the AV node?

<p>To delay the transmission of electrical signals from atria to ventricles (C)</p> Signup and view all the answers

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