18 Questions
What is the primary site of fatty acid synthesis in most animal tissues?
Cytosol
Which of the following is NOT a cofactor required for acetyl-CoA carboxylation?
Bioreactor
What is the product of the committed step in fatty acid synthesis?
Malonyl-CoA
In which of the following tissues is fatty acid synthesis less prominent?
Skeletal muscle
What is the mechanism by which acetyl-CoA units are transported out of the mitochondrial matrix?
Citrate shuttle
What is the maximum length of fatty acid chains synthesized through the fatty acid synthesis pathway?
C16
What is the role of ATP in the first step of lipogenesis?
To carboxylate biotin
What is the effect of high fat diets on the regulation of acetyl-CoA carboxylase?
Decreased activity
Which of the following domains of the fatty acid synthase complex is involved in the release of palmitate?
Domain 3
What is the role of malonyl-CoA in the regulation of lipogenesis?
Activator of fatty acid synthase
What is the effect of insulin on the regulation of lipogenesis?
Activates lipogenesis
What is the role of the –SH group of the ACP in the condensation reaction of lipogenesis?
Accepts the acetyl group from acetyl-CoA
What is the role of enoyl reductase enzyme in the spiral of fatty acid synthesis?
To reduce the crotonyl-enzyme to butyryl-enzyme
What is the outcome of the first turn in the spiral of fatty acid synthesis?
Formation of a C4-acyl enzyme
What is the function of the SH group of ACP in the fatty acid synthesis pathway?
To bind to and displace the saturated acyl residue
What is the fate of the C16-acyl enzyme formed in the fatty acid synthesis pathway?
It is not a substrate for the condensing enzyme and is released as free palmitate
What is the role of the thiol groups of cysteine residues in the fatty acid synthesis pathway?
To bind to the acetyl-CoA and malonyl-CoA molecules
How many times is the elongation step repeated in the fatty acid synthesis pathway?
6 times
Test your understanding of the fatty acid synthesis process, including the reduction of crotonyl-enzyme and the role of NADPH and malonyl-CoA. This quiz covers the steps involved in the spiral of fatty acid synthesis, from the first turn to the elongation step. Evaluate your knowledge of this biochemical process!
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
