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Questions and Answers
How are the enzymes each monomer of the fatty acid synthase complex arranged?
How are the enzymes each monomer of the fatty acid synthase complex arranged?
- Acetyl synthase, Malonyl reductase, Ketoacyl reductase, Hydratase, Enoyl transacylase, Thioesterase
- Malonyl transacylase, Acetyl tansacylase, Ketoacyl reductase, Enoyl reductase, Hydratase, Thioesterase
- Acetyl tansacylase, Malonyl tansacylase, Ketoacyl synthase, Ketoacyl reductase, Hydratase, Enoyl reductase, Thioesterase (correct)
- Acetyl transacylase, Ketoacyl synthase, Malonyl tansacylase, Enoyl reductase, Hydratase, Thioesterase
Which enzyme is immediately after Malonyl transacylase in the fatty acid synthase complex?
Which enzyme is immediately after Malonyl transacylase in the fatty acid synthase complex?
- Enoyl reductase
- Acetyl transacylase
- Ketoacyl synthase (correct)
- Thioesterase
What is the role of the 4'-phosphopantetheine group in the fatty acid synthase complex?
What is the role of the 4'-phosphopantetheine group in the fatty acid synthase complex?
- It catalyzes the final step of fatty acid elongation.
- It acts as a template for fatty acid synthesis.
- It anchors the enzymes to the polypeptide chain.
- It facilitates the interaction between adjacent monomers. (correct)
Which of the following statements about the fatty acid synthase complex in humans is true?
Which of the following statements about the fatty acid synthase complex in humans is true?
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Which of the following is NOT one of the seven enzymes present in the fatty acid synthase complex?
Which of the following is NOT one of the seven enzymes present in the fatty acid synthase complex?
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Study Notes
Fatty Acid Synthase Complex
- Fatty acid synthase complex in humans is a dimer consisting of two identical monomers.
- Each monomer contains seven enzymes of fatty acid synthase on one polypeptide chain.
Enzyme Composition
- The seven enzymes present in each monomer are arranged in order of their contribution in step II reactions (6 reactions).
- Enzymes include: acetyl transacylase, malonyl transacylase, ketoacyl synthase, ketoacyl reductase, hydratase, enoyl reductase, and thioesterase.
Important Interactions
- The -SH of 4'-phosphopantetheine of one monomer is in close proximity to the -SH of the cysteine residue of the other monomer.
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Description
Learn about the composition and arrangement of enzymes in the fatty acid synthase complex, a crucial enzyme for fatty acid synthesis in humans.
