Fate of RBCs in the Blood Stream
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Questions and Answers

What is the average life span of RBCs in the bloodstream?

  • 120-150 days
  • 60-90 days
  • 90-120 days (correct)
  • 150-180 days
  • Where does lysis of RBCs normally occur?

  • Heart
  • Lungs
  • Liver, spleen, and bone marrow (correct)
  • Kidneys
  • How many RBCs are broken down in the human body approximately every hour?

  • 50-100 million
  • 20-50 million
  • 200-300 million
  • 100-200 million (correct)
  • What happens to Fe2+ after the breakdown of RBCs?

    <p>Transported with transferrin for next heme biosynthesis</p> Signup and view all the answers

    Which process describes the breakdown of RBCs occurring outside of the bloodstream in the reticuloendothelial system?

    <p>Extravascular lysis in the ER</p> Signup and view all the answers

    Which other hemoproteins contain heme groups that are degraded by the same pathway as Hb?

    <p><em>Cytochrome c</em></p> Signup and view all the answers

    What is the fate of Fe2+ after being transported with transferrin post-breakdown of RBCs?

    <p>Utilized in the synthesis of heme</p> Signup and view all the answers

    Where in the human body does the breakdown of RBCs lead to the production of new heme through a specific pathway?

    <p>Bone marrow</p> Signup and view all the answers

    Apart from Hb, which other type of protein contains heme groups that follow a similar degradation pathway?

    <p>Myoglobin</p> Signup and view all the answers

    In the human body, approximately how many RBCs are broken down every hour?

    <p>100-200 million</p> Signup and view all the answers

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