Fascioliasis Overview and Impact
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Questions and Answers

Which of the following parasites is NOT a known cause of fascioliasis in humans?

  • Fasciolopsis buski
  • Fasciola hepatica
  • Fasciola gigantica
  • Clonorchis sinensis (correct)
  • What is the primary habitat of Fasciola hepatica in its definitive hosts?

  • Intestinal tract
  • Liver parenchyma
  • Bile ducts (correct)
  • Circulatory system
  • What is the size of an ovum produced by Fasciola species?

  • 120 x 60 µ
  • 150 x 80 µ (correct)
  • 100 x 50 µ
  • 180 x 100 µ
  • In the life cycle of Fasciola hepatica, what role does the snail Lymnaea cailliaudi play?

    <p>Intermediate host</p> Signup and view all the answers

    How long can encysted metacercariae remain viable in their environment?

    <p>6 months</p> Signup and view all the answers

    What is the first developmental stage of Fasciola observed after the ovum matures in water?

    <p>Miracidium</p> Signup and view all the answers

    Which of the following statements about the oral and ventral suckers of the adult Fasciola is accurate?

    <p>The adult is leaf-like with distinct suckers.</p> Signup and view all the answers

    What is a common mode of human infection with Fasciola?

    <p>Eating metacercariae-contaminated vegetables</p> Signup and view all the answers

    What is the definitive host for Fascioliasis?

    <p>Herbivorous animals and humans</p> Signup and view all the answers

    Which stage is considered the infective stage in the life cycle of Fasciola spp.?

    <p>Encysted metacercaria</p> Signup and view all the answers

    What clinical feature is NOT associated with the acute phase of Fascioliasis?

    <p>Liver rot</p> Signup and view all the answers

    Which of the following describes Halzoun syndrome?

    <p>Pharyngeal fascioliasis leading to pharyngitis and laryngeal edema</p> Signup and view all the answers

    How is Fascioliasis primarily diagnosed?

    <p>Microscopic identification of eggs in stool</p> Signup and view all the answers

    What should be avoided to help prevent Halzoun syndrome?

    <p>Eating raw liver</p> Signup and view all the answers

    Which host serves as the intermediate host for Fasciola spp.?

    <p>Snail Lymnaea cailliaudi</p> Signup and view all the answers

    What is a common mode of infection for Fascioliasis?

    <p>Ingestion of encysted metacercaria in contaminated water or plants</p> Signup and view all the answers

    Study Notes

    Fascioliasis

    • Fascioliasis is a parasitic disease caused by Fasciola hepatica and Fasciola gigantica.
    • These parasites infect herbivores but can accidentally infect humans.
    • The parasites are Platyhelminthes (flatworms), specifically Trematoda (flukes).
    • Three species infect humans: Fasciola hepatica, Fasciola gigantica, and Fasciolopsis buski (lives in the small intestine).

    Morphology of the Adult

    • Adult flukes are leaf-shaped.
    • The fluke has an oral sucker and a larger ventral sucker.
    • The male reproductive system begins with two branched testes in the middle of the body.
    • The female reproductive system includes a branched (lobed) ovary.

    Life Cycle

    • The parasite lives in the bile ducts of humans and herbivores (definitive hosts).
    • Eggs pass with bile to the intestine and are expelled in feces.
    • In water, the egg develops into a miracidium (a free-swimming stage).
    • The miracidium infects a snail (intermediate host) Lymnaea cailliaudi or L. truncatula.
    • Inside the snail, the parasite develops through sporocyst, rediae, and cercariae stages.
    • Cercariae leave the snail and settle on vegetation.
    • Encysting forms metacercariae, an infective stage.
    • Humans become infected by consuming food contaminated with encysted metacercariae.
    • The cyst dissolves in the intestine, and the young worm migrates to the liver via the peritoneal cavity and reaches the bile ducts.

    Mode of Infection

    • Humans become infected by ingesting freshwater plants or water contaminated with metacercariae.
    • A subtype called Pharyngeal fascioliasis occurs by eating raw infected liver.

    Important Points

    • Definitive host: herbivorous animals and humans.
    • Infection site: bile ducts
    • Intermediate host: Lymnaea cailliaudi.
    • Infective stage: encysted metacercaria.
    • Diagnostic stage: eggs in stool.
    • Mode of infection: ingestion of encysted metacercaria.
    • Infection route: oral

    Clinical Features

    • Acute phase (fluke migration through the liver): abdominal pain, hepatomegaly, fever, vomiting, diarrhea, eosinophilia.
    • Chronic phase (adult fluke within the bile ducts): biliary obstruction, inflammation, liver rot.

    Laboratory Diagnosis

    • Microscopic identification of eggs in stool.
    • Eggs can be detected in stool or in material obtained by duodenal or biliary drainage.

    Control & Prevention

    • Treat infected animals.
    • Control snail populations.
    • Avoid eating raw vegetables before washing them.
    • Avoid drinking contaminated water.
    • Avoid eating raw liver.

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    Lecture 8 - Fascioliasis PDF

    Description

    Explore the parasitic disease Fascioliasis caused by Fasciola hepatica and Fasciola gigantica. This quiz covers its geographic distribution, morphology, and impact on humans and herbivores. Test your knowledge and learn about this significant health concern.

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