Fasciola hepatica and Clonorchis sinensis Quiz

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Questions and Answers

What clinical symptom might develop if flukes block the bile ducts?

  • Neuropathic pain
  • Obstructive jaundice (correct)
  • Pulmonary edema
  • Hypertension

What is one of the methods used to diagnose fasciolosis?

  • Demonstration of eggs in stool (correct)
  • Blood culture
  • CT scan of the liver
  • Ultrasound examination

What step is recommended to confirm or reject a suspected diagnosis of fasciolosis?

  • Stop eating raw liver for a week (correct)
  • Increase water intake
  • Stop consuming alcohol for a week
  • Start a high-fiber diet

Which organism serves as the definitive host for Clonorchis sinensis?

<p>Humans (D)</p> Signup and view all the answers

What is one of the geographic regions where Clonorchis sinensis is endemic?

<p>China (A)</p> Signup and view all the answers

Flashcards

Clonorchosis

The Chinese liver fluke, Clonorchis sinensis, causes clonorchosis. This parasitic infection is endemic and anthropozoonotic, meaning it is common in specific areas and can be transmitted between animals and humans.

Clonorchis sinensis Morphology

The adult fluke is about 1 cm long and narrower than Fasciola hepatica. It has an operculated egg, measuring 25-30 micrometers.

Clonorchis sinensis Definitive Hosts

Humans are the definitive host for Clonorchis sinensis, but it also infects dogs, cats, pigs, and other mammals. This makes control challenging due to the numerous reservoir hosts.

Clonorchis sinensis Intermediate Hosts

Freshwater snails serve as the first intermediate host for Clonorchis sinensis, and freshwater fish act as the second intermediate host.

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Clonorchis sinensis Life Cycle

The life cycle of Clonorchis sinensis involves adult flukes releasing eggs into the intestine, which are then passed in feces. These eggs are ingested by freshwater snails, where they develop into cercariae. The cercariae infect freshwater fish, becoming metacercariae. Humans get infected by consuming raw or undercooked fish containing metacercariae.

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Study Notes

Fasciola hepatica

  • Pathogenicity: Causes various symptoms including nausea, vomiting, fever, pain, allergic reactions, diarrhea, hepatomegaly (enlarged liver), and eosinophilia.
  • Complications: Blockage of bile ducts can lead to obstructive jaundice. Severe cases can result in liver cirrhosis (scarring) and hepatic failure. Chronic infection involves liver inflammation with abscess formation (liver rot).
  • Diagnosis: Detection of eggs in stool or bile (obtained via duodenal intubation). A follow-up stool examination after a week of avoiding raw liver can help confirm or rule out fasciolosis.
  • Prevention: Avoiding raw/unwashed vegetables, fruits, and contaminated water. Eradication in animal reservoirs, and draining fields to eliminate snail hosts are key preventive measures.

Clonorchis sinensis

  • Disease: Causes clonorchosis, an endemic and anthropozoonotic parasitic infection.
  • Geographic Distribution: Primarily found in China and Japan.
  • Habitat: Infects bile ducts.
  • Morphology: Adult worms are approximately 1 cm long and narrower than Fasciola hepatica. Eggs are operculated (lidded) and measure 25-30 micrometers.
  • Life Cycle:
    • Definitive host is humans, but also affects dogs, cats, pigs and other mammals.
    • First intermediate host: freshwater snails.
    • Second intermediate host: freshwater fish.
    • Adult flukes release eggs into the intestines via bile ducts, then eggs are passed in stool.

Paragonimus westermani

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