Questions and Answers
What is the generic name of Farxiga?
What is Farxiga effective for?
Lowering blood sugar in diabetics.
What primary condition is Farxiga prescribed for?
Type 2 diabetes.
What benefits were demonstrated by clinical data for Farxiga?
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What are the common adverse reactions associated with Farxiga?
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List some side effects of Farxiga.
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How is Farxiga dosed?
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When should Farxiga be administered?
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What is the mechanism of action of Farxiga?
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What are the contraindications for Farxiga?
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Study Notes
Farxiga Overview
- Generic name: Dapagliflozin, classified as an SGLT2 inhibitor.
- Effective in lowering blood sugar levels in individuals with type 2 diabetes.
Efficacy & Indications
- Used as an adjunct to diet and exercise for managing high blood sugar in adults with type 2 diabetes.
- Clinical studies show significant reductions in A1C levels along with benefits in weight management and blood pressure.
Clinical Data & Safety
- Supported by evidence from 12 placebo-controlled studies highlighting various safety assessments.
- Common adverse reactions include:
- Female genital mycotic infections
- Nasopharyngitis
- Urinary tract infections
Side Effects
- Notable side effects include:
- Back pain
- Increased urination
- Male genital mycotic infections
- Nausea
- Dyslipidemia
- Constipation
- Discomfort while urinating
- Pain in extremities
Dosing & Administration
- Initial dosing is 5mg once daily, which can be adjusted to 10mg for further A1C control.
- Can be taken in the morning, with or without food.
Mechanism of Action
- Acts by inhibiting SGLT2, enabling glucose and associated calories to be excreted through urine.
- This process lowers the renal threshold for glucose, promoting increased urinary glucose excretion.
- On average, leads to the removal of approximately 70g of glucose (around 280 calories) per day after 12 weeks of treatment.
Contraindications
- Prior serious hypersensitivity reactions to Farxiga.
- Presence of severe renal impairment (eGFR).
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Description
Test your knowledge on Farxiga, a medication used for managing type 2 diabetes. This quiz covers its generic name, efficacy, indications, and clinical data. Perfect for learners looking to understand diabetes treatment options.
