Farxiga Flashcards: Diabetes Medication
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Questions and Answers

What is the generic name of Farxiga?

  • Dapagliflozin (correct)
  • Glyburide
  • Metformin
  • SGLT2

    • What is Farxiga effective for?

    Lowering blood sugar in diabetics.

    What primary condition is Farxiga prescribed for?

    Type 2 diabetes.

    What benefits were demonstrated by clinical data for Farxiga?

    <p>Reductions in A1C levels.</p> Signup and view all the answers

    What are the common adverse reactions associated with Farxiga?

    <p>Female genital mycotic infections, nasopharyngitis, and urinary tract infections.</p> Signup and view all the answers

    List some side effects of Farxiga.

    <p>Back pain, increased urination, male genital mycotic infections, nausea, dyslipidemia, constipation, discomfort with urination, pain in extremity.</p> Signup and view all the answers

    How is Farxiga dosed?

    <p>Once daily at a 5mg starting dose, which can be increased to 10mg.</p> Signup and view all the answers

    When should Farxiga be administered?

    <p>In the morning.</p> Signup and view all the answers

    What is the mechanism of action of Farxiga?

    <p>By inhibiting SGLT2, it increases urinary glucose excretion.</p> Signup and view all the answers

    What are the contraindications for Farxiga?

    <p>Prior serious hypersensitivity reaction to Farxiga and severe renal impairment.</p> Signup and view all the answers

    Study Notes

    Farxiga Overview

    • Generic name: Dapagliflozin, classified as an SGLT2 inhibitor.
    • Effective in lowering blood sugar levels in individuals with type 2 diabetes.

    Efficacy & Indications

    • Used as an adjunct to diet and exercise for managing high blood sugar in adults with type 2 diabetes.
    • Clinical studies show significant reductions in A1C levels along with benefits in weight management and blood pressure.

    Clinical Data & Safety

    • Supported by evidence from 12 placebo-controlled studies highlighting various safety assessments.
    • Common adverse reactions include:
      • Female genital mycotic infections
      • Nasopharyngitis
      • Urinary tract infections

    Side Effects

    • Notable side effects include:
      • Back pain
      • Increased urination
      • Male genital mycotic infections
      • Nausea
      • Dyslipidemia
      • Constipation
      • Discomfort while urinating
      • Pain in extremities

    Dosing & Administration

    • Initial dosing is 5mg once daily, which can be adjusted to 10mg for further A1C control.
    • Can be taken in the morning, with or without food.

    Mechanism of Action

    • Acts by inhibiting SGLT2, enabling glucose and associated calories to be excreted through urine.
    • This process lowers the renal threshold for glucose, promoting increased urinary glucose excretion.
    • On average, leads to the removal of approximately 70g of glucose (around 280 calories) per day after 12 weeks of treatment.

    Contraindications

    • Prior serious hypersensitivity reactions to Farxiga.
    • Presence of severe renal impairment (eGFR).

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    Description

    Test your knowledge on Farxiga, a medication used for managing type 2 diabetes. This quiz covers its generic name, efficacy, indications, and clinical data. Perfect for learners looking to understand diabetes treatment options.

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