Podcast
Questions and Answers
In the author's dream, what was he desperately trying to do?
In the author's dream, what was he desperately trying to do?
- Catch falling eggs with a padded basket. (correct)
- Stop someone from tossing eggs from a building.
- Find medical scrubs that fit properly.
- Outrun a pursuer in a Baltimore-like city.
What surgical procedure did the author's hospital specialize in?
What surgical procedure did the author's hospital specialize in?
- Laparoscopic appendectomy.
- Whipple procedure. (correct)
- Organ transplantation.
- Coronary artery bypass grafting.
What realization led the author to quit medicine initially?
What realization led the author to quit medicine initially?
- He was not as good at surgery as his colleagues were.
- The long-term futility of cancer surgeries. (correct)
- The surgeries were too complex and stressful.
- The high mortality rate of surgery patients.
The author's dream about the falling eggs ultimately symbolized what?
The author's dream about the falling eggs ultimately symbolized what?
What crucial detail did the mythical Greek, Tithonus, forget to ask for, resulting in a decaying body despite eternal life?
What crucial detail did the mythical Greek, Tithonus, forget to ask for, resulting in a decaying body despite eternal life?
What supplanted 'fast' causes of death in the 20th century?
What supplanted 'fast' causes of death in the 20th century?
Healthspan is best defined as:
Healthspan is best defined as:
What is the second part of the plan for longevity?
What is the second part of the plan for longevity?
What was the basic script that physicians used to treat both trauma victims and chronic disease sufferers?
What was the basic script that physicians used to treat both trauma victims and chronic disease sufferers?
Progress in modern medicine has been less than stellar except for which of the following?
Progress in modern medicine has been less than stellar except for which of the following?
According to the American Diabetes Association, a patient is considered to have diabetes when they have a hemoglobin Alc (HbA1c) test result reach what percentage?
According to the American Diabetes Association, a patient is considered to have diabetes when they have a hemoglobin Alc (HbA1c) test result reach what percentage?
On September 8, 2009, the author had a bucket-list long-distance swim was from Los Angeles to what island?
On September 8, 2009, the author had a bucket-list long-distance swim was from Los Angeles to what island?
The author states that one's family tree was full of men had died in their forties of what?
The author states that one's family tree was full of men had died in their forties of what?
Modern medicine has gotten crucial things dead wrong about the Horsemen, what will be examined in this book?
Modern medicine has gotten crucial things dead wrong about the Horsemen, what will be examined in this book?
According to the author what becomes critically important as we age?
According to the author what becomes critically important as we age?
At what point did the author's ICU nurse offer the medication to the patient?
At what point did the author's ICU nurse offer the medication to the patient?
Who first articulated what we now know as the scientific method, an idea of medicine 2.0?
Who first articulated what we now know as the scientific method, an idea of medicine 2.0?
What do we need long-range radar and GPS, and satellite imaging for?
What do we need long-range radar and GPS, and satellite imaging for?
What best describes what one must be in medicine 3.0, according to the context?
What best describes what one must be in medicine 3.0, according to the context?
In the boxing match example in the reading, what was Muhammad Ali's objective?
In the boxing match example in the reading, what was Muhammad Ali's objective?
According to the author, what is the key to victory when trying to achieve objectives?
According to the author, what is the key to victory when trying to achieve objectives?
The author uses the analogy that for us humans, our risk of death and disease does which of the following to us?
The author uses the analogy that for us humans, our risk of death and disease does which of the following to us?
According to the reading we've been provided, what is the powerful risk factor do the Horseman diseases have in common?
According to the reading we've been provided, what is the powerful risk factor do the Horseman diseases have in common?
Most people tend to suffer through a period of decline, the author argues they are...
Most people tend to suffer through a period of decline, the author argues they are...
What should be our goal, according to the author, with the deterioration of healthspan?
What should be our goal, according to the author, with the deterioration of healthspan?
Our tactics in Medicine 3.0 fall into five broad domains. What is not in those domains?
Our tactics in Medicine 3.0 fall into five broad domains. What is not in those domains?
What are the two requirements of the scientific method, as the author explained from Richard Feynman?
What are the two requirements of the scientific method, as the author explained from Richard Feynman?
After he disobeyed the order from his bosses, Sehgal smuggled a jar of rapamycin and hid it where?
After he disobeyed the order from his bosses, Sehgal smuggled a jar of rapamycin and hid it where?
Where does the author state their group met before embarking to Easter Island?
Where does the author state their group met before embarking to Easter Island?
The loss of the ability store fat is potentially linked to what?
The loss of the ability store fat is potentially linked to what?
Because the test may be very difficult to handle on the brain (Alzheimer's), the author's team has what member available?
Because the test may be very difficult to handle on the brain (Alzheimer's), the author's team has what member available?
How long is the shortest time frame in which colon cancer can develop?
How long is the shortest time frame in which colon cancer can develop?
The author says the long and difficult to administer such that they are best suited to what type of specialist?
The author says the long and difficult to administer such that they are best suited to what type of specialist?
It is a common symptom of what health issue for a patient to mention stomach pains, weight gain, continual thirst?
It is a common symptom of what health issue for a patient to mention stomach pains, weight gain, continual thirst?
Women are at a greater increased adjust-risk for what?
Women are at a greater increased adjust-risk for what?
The author writes 'I what before a patient will have to tell someone they have have cancer suffering from cancer'
The author writes 'I what before a patient will have to tell someone they have have cancer suffering from cancer'
Why did the author sob in the stairwell wish?
Why did the author sob in the stairwell wish?
Where did the author find the code was?
Where did the author find the code was?
How many years of medical training did the author throw out the window?
How many years of medical training did the author throw out the window?
As described in the text, how many Americans are thought develop cancer?
As described in the text, how many Americans are thought develop cancer?
What is is still the ultimate successor to diseases to have, the worst of the Horsemen?
What is is still the ultimate successor to diseases to have, the worst of the Horsemen?
The text gives an analogy for the body's vascular network, what is it?
The text gives an analogy for the body's vascular network, what is it?
Why do statin do.
Why do statin do.
The text states if all other things equal, which one what has a lower metabolic leeway?
The text states if all other things equal, which one what has a lower metabolic leeway?
What was the author's reaction to the resident's suggestion to delay gentamicin administration?
What was the author's reaction to the resident's suggestion to delay gentamicin administration?
What was the author's primary emotion when faced with the prospect of giving 'horrible news to people' at the bank?
What was the author's primary emotion when faced with the prospect of giving 'horrible news to people' at the bank?
What concept from finance and banking did the author recognize to have a huge blind spot medicine?
What concept from finance and banking did the author recognize to have a huge blind spot medicine?
According to the author, what is often implied by the statement 'First, do no harm'?
According to the author, what is often implied by the statement 'First, do no harm'?
What key element was notably absent from the discussion of absolute certainty throughout the chapter?
What key element was notably absent from the discussion of absolute certainty throughout the chapter?
What does Medicine 3.0 demand from patients, differing from Medicine 2.0?
What does Medicine 3.0 demand from patients, differing from Medicine 2.0?
Beyond extending the duration of life at what is Medicine 3.0 aiming?
Beyond extending the duration of life at what is Medicine 3.0 aiming?
What common risk factor do the Four Horsemen (heart disease, cancer, neurodegenerative disease, and type 2 diabetes) share, according to the text?
What common risk factor do the Four Horsemen (heart disease, cancer, neurodegenerative disease, and type 2 diabetes) share, according to the text?
What does a mathematical function allow the author to visualize, in terms of longevity for his patients?
What does a mathematical function allow the author to visualize, in terms of longevity for his patients?
What was the real strategy that made Ali fight and win, according to the text?
What was the real strategy that made Ali fight and win, according to the text?
Why did the author and his friends want to visit Easter Island?
Why did the author and his friends want to visit Easter Island?
Who prevented the destruction of the Rapamycin strains?
Who prevented the destruction of the Rapamycin strains?
What is the main function of mTOR?
What is the main function of mTOR?
How did the findings regarding rapamycin challenge previous scientific assumptions?
How did the findings regarding rapamycin challenge previous scientific assumptions?
What potential benefit of caloric restriction (CR) is specific for inside a laboratory?
What potential benefit of caloric restriction (CR) is specific for inside a laboratory?
Why should people be worried about eating glucose versus fructose?
Why should people be worried about eating glucose versus fructose?
What can result after a increase in body weight?
What can result after a increase in body weight?
What did Reaven label related collection of related disorders that was determined by the X actor, insulin resistance?
What did Reaven label related collection of related disorders that was determined by the X actor, insulin resistance?
Outside of just being a general weight issue, what's does what makes fat dangerous?
Outside of just being a general weight issue, what's does what makes fat dangerous?
What does the Yale university endocrinologist reveal to be the necessity to test often for?
What does the Yale university endocrinologist reveal to be the necessity to test often for?
Rather there is a correlation for Alzheimer's, the presence of Ab plaques, is it that there are no signs?
Rather there is a correlation for Alzheimer's, the presence of Ab plaques, is it that there are no signs?
About how many years has 3 scientists found that it was useful to intervened with patients suffering from with high mood change
About how many years has 3 scientists found that it was useful to intervened with patients suffering from with high mood change
Who did a few Alzheimer observations in 1906, discovering and observing?
Who did a few Alzheimer observations in 1906, discovering and observing?
What action marked when the author became invested into longevity?
What action marked when the author became invested into longevity?
According to the reading, what is an element when the author has a new patient?
According to the reading, what is an element when the author has a new patient?
Based off the text, about where did the author and his friends take a trip together?
Based off the text, about where did the author and his friends take a trip together?
Which statement about evolutionary change is the most accurate?
Which statement about evolutionary change is the most accurate?
What was the amount of time had occurred for deaths to drop by two-thirds as possible exception, in the industrialized world?
What was the amount of time had occurred for deaths to drop by two-thirds as possible exception, in the industrialized world?
Who does Semmelweis believe that doctors were transmitting something to?
Who does Semmelweis believe that doctors were transmitting something to?
What's a good thing to keep a eye on when analyzing cholesterol?
What's a good thing to keep a eye on when analyzing cholesterol?
When comparing it to normal people, how can one account for the comparison of the centenarians?
When comparing it to normal people, how can one account for the comparison of the centenarians?
When you're older, the text mentions that you do have to worry about things, what was what it used as an example from when the time what?
When you're older, the text mentions that you do have to worry about things, what was what it used as an example from when the time what?
In a medical world, what are people who study aging?
In a medical world, what are people who study aging?
What is a classic symptom of diabetes, as the character Alvise Cornaro put?
What is a classic symptom of diabetes, as the character Alvise Cornaro put?
As mentioned what we need to do if we're going to live longer.
As mentioned what we need to do if we're going to live longer.
What did Ali want to do to Foreman?
What did Ali want to do to Foreman?
What was the woman complaining about when she was in the ER?
What was the woman complaining about when she was in the ER?
What was the name of the drug that the author had a frustrating time with?
What was the name of the drug that the author had a frustrating time with?
What was the disease when the author's mother contracted at seventy?
What was the disease when the author's mother contracted at seventy?
What does Medicine 3.0 puts a larger emphasis on?
What does Medicine 3.0 puts a larger emphasis on?
What has Science been making that was able to make them understand disease?
What has Science been making that was able to make them understand disease?
How exactly can cognitive and emotional deterioration will do?
How exactly can cognitive and emotional deterioration will do?
Under what circumstances can it be said for when a disease will have happen to someone?
Under what circumstances can it be said for when a disease will have happen to someone?
Flashcards
Whipple procedure
Whipple procedure
Involves removing the head of the patient's pancreas and the upper part of the small intestine
Healthspan
Healthspan
The period of life when we are free from disability or disease.
Achieving Longevity
Achieving Longevity
To live longer and live better for longer
Medicine 3.0
Medicine 3.0
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Medicine 3.0
Medicine 3.0
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Medicine 3.0
Medicine 3.0
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Medicine 3.0
Medicine 3.0
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The goal
The goal
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Marginal Decade
Marginal Decade
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Our objective
Our objective
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blackline
blackline
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Tactics
Tactics
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strategy
strategy
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Risk
Risk
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Problem
Problem
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Living longer
Living longer
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Aging
Aging
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Unfortunately
Unfortunately
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Longevity
Longevity
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Infection
Infection
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Exercise
Exercise
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Caloric restriction
Caloric restriction
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AMPK or AMP
AMPK or AMP
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Rapamycin
Rapamycin
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What the future involves
What the future involves
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Non-essential
Non-essential
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Understanding risk
Understanding risk
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Our goal
Our goal
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Exercise
Exercise
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Outlive
Outlive
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What is time
What is time
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Just because
Just because
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Metabolic disorder
Metabolic disorder
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Our goal
Our goal
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Why longevity genes
Why longevity genes
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The point
The point
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To me longevity
To me longevity
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Has changed the world
Has changed the world
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To be in a better step
To be in a better step
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Foxo3
Foxo3
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Distinction
Distinction
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Study Notes
Introduction
- This books objective is to highlight the importance of new ways to approach a situation or mindset
Dream Interpretation
- The author dreams of trying to catch falling eggs in a dirty city resembling Baltimore while holding a padded basket
- In the dream, there are too many eggs to catch, leaving them overwhelmed and feeling helpless
Career History
- Surgical resident at Johns Hopkins Hospital training to be a cancer surgeon, working 24-hour shifts
- Pancreatic cancer outcomes improved: 99% survival rate 30 days post-Whipple Procedure
- Quit medicine due to frustration with cancer treatment's futility
- Later the author returned to medicine
- The author realized the problem was stopping who throws the eggs
Key Point
- It's essential approach situations like "falling eggs" with a different mindset and tools to solve problems
The First Patient
- The Author will never forget their time working at a hospital
- The author remembers a woman in her 30's who came into their ER
- The woman was from East Palo Alto and complained of shortness of breath.
- The woman suddenly lost her breath and lost consciousness
- She passed away despite all efforts to save her
Inner-City Baltimore
- Fast Deaths rule in Baltimore due to to guns knives, and speeding. Which was a main “feature" of the training
- It's an excellent place to learn as a surgeon to repairing bodies
Trauma vs Cancer
- Trauma dominates night time vs the cancer
- It is always worse when a patient is not living to fight cancer.
- As humans we should be intervening to help people before waiting for diagnosis
Longevity
- The focus as doctor should not only based on longevity. It starts by defining what Longevity and what it means from medical professionals
- Longevity does not simply mean merely notching more and more birthdays as we slowly wither away (Tithonus)
Health Span Vs. Life Span
- Longevity has two components such as chronological lifespan and the quality of life. Which is also defined as a health span
- In 1900s, Life expectancy was hovering south of age 50
- Today, the chronic dieases such as, heart disease, cancer, neurodegenerative disease, etc
The Core Principles
- The key question is, Where am I headed from here? What's my future trajectory?
- You need to start thinking about it and taking action now
- Focus on longevity; you cannot fix fast death more effectively than slow death in
- Cancer, cardiovascular disease, neurological disease
Common Methods
- The standard treatment guidelines of the American Diabetes Association specify that a patient can be diagnosed with diabetes mellitus when they return a hemoglobin Alc of 6.5 percent or higher
- If AlC is close to 6.4 they are identified as pre diabeetes
A day to remember
- September 8, 2009, Jill, had said “Peter, I think you should on working on a little thinning up"
- Peter had ballooned up to 210 pounds, my testosterone levels below the 5th percentile
- That's why peter focus towards nutrition, metabolism and the biggest point, Longevity
Understanding
- The modern medicine does not really have a handle on the Chronic Diseases of agining!
- Modern medicines have gotten key elements wrong about the main root cases
Health & Wellness
- With more focus, The typical cholesterol panel (bad/good cholesterol) that and discuss and discuss doesnt have near
- If the world needs one, Longevity can be found by dieting specific foods, meditating, eat super foods and maintain the“energy" properly, death can become very scientific
- The world always figures how to unplug aging by finding a way for genes to be changed for each History
What is OUTLIVE
- It is a way to live longer and feel better to feel better each day.
- To extend your lifespan by a possible decade and feel 20 years younger
- Focus should stay to improve health span and waiting un the body declined
Johns Hopkins
- The author does is not remember what the very last thing that he wanted to work with frustration at Johns Hopkins
- Johns Hopkins fellow a trainee who was one level above the hospital pecking order, She said. Just have them give it at seven
- But instead, she turned and gave me a tongue-lashing
- People have trouble in the industry but found a place in the right spots
The Key Word is RISK
- McKinsey originally wanted the author to enter health care but instead studied the magnitude about the way we to.
- The job was to help new new U.S companies to maintain enough coverage to help the unexpected
- Later his work comes to an end then a key idea to survival to great investors
First do no harm
- The trouble of medicine began because of Hippocrates
- But Hippocrates never had the right to say Hippocrates. Some people feel the treatment option is alway the easiest
- His first trauma calls included what he took as a resident a 17 year old came in with a stab wound
- So even if though doctor had a mistake 4 days later the doctor went back to normal
How to calculate risk
- Medicine with calculating life is base around the calculation of risk
- A doctor needs to do anything with out risk or the physician has never done much to help a patient too
- Hippocrates now has a bright electric lights
Three medicines
- There has been been two medicines and on the verse of the third
- The mid nineteenth century came with germ and ultimate the antibiotics but it was clear that the Louis Pasle and Rober Koch
- .But overall was not that much more success with the use of antibiotic into the early 20th century
The bank and Risk
- The bank problem were not a the bank the seemed minor for medical
- Their seems minor risk compounded in to unstoppable problems. The Chronic diseases work in a similar fashion. As they get to old its hard to make to away.
A new way to treat
- That Medicine 3 Is not a new way to path up and over turn the doors and tumors and hoping for the best
Personalized Precision Medicine
- It is clear all has its different values. The goal of medicine is
- Improved technology enable many people to better themselves to monitoring what all the human better them become them
Medicine 3.0 points
- Medicine 3.0 places a far greater emphasis on prevention more than treatment. When do know build the ark
- Second, Medicine 3.0 considers the patient as a unique individual. Medicine 2.0 treats everyone as basically the same.
- the fourth, in different the ways that we have lives life span to maintaining health and quilty life
How much you depend on the tools
- We approached our cancer is the that people to like
- His visual son were good to we will done. And high all of the test
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Description
Highlighting the importance of adopting new mindsets and tools to solve problems, particularly when facing overwhelming situations. Drawing from experiences in surgical residency and dream interpretation, the lesson emphasizes changing the approach to prevent problems rather than just managing their consequences.
