Podcast
Questions and Answers
Why is D-Glucose sweet, but L-glucose has a slightly salty taste?
Why is D-Glucose sweet, but L-glucose has a slightly salty taste?
- L-glucose has an additional functional group that alters its taste.
- D-Glucose has more hydroxyl groups than L-glucose.
- The acidity of L-glucose makes it taste salty.
- The stereochemistry of glucose affects its taste. (correct)
Which type of flavoring materials are considered effective in masking the taste of bitter drugs?
Which type of flavoring materials are considered effective in masking the taste of bitter drugs?
- Fruit-flavored vehicles
- Cocoa-flavored vehicles (correct)
- Salty-flavored vehicles
- Citrus-flavored vehicles
Why is the selection of flavoring agents important based on the age of the patient?
Why is the selection of flavoring agents important based on the age of the patient?
- Certain flavors react differently with the digestive system in children.
- The taste buds of children are more sensitive than adults.
- Different age groups prefer different flavors. (correct)
- The metabolism of flavoring agents varies with age.
What type of flavors are frequently used to combat sour or acid-tasting drugs?
What type of flavors are frequently used to combat sour or acid-tasting drugs?
How do structural changes impact the taste of compounds according to the text?
How do structural changes impact the taste of compounds according to the text?
Why are cocoa-flavored vehicles considered effective for bitter drugs?
Why are cocoa-flavored vehicles considered effective for bitter drugs?
Which statement about the oil-water partition coefficient is true?
Which statement about the oil-water partition coefficient is true?
What is the primary factor that determines the extent of drug dissociation or ionization?
What is the primary factor that determines the extent of drug dissociation or ionization?
Which statement about hygroscopic powders is true?
Which statement about hygroscopic powders is true?
What is the primary reason for adjusting the pH of the vehicle in drug formulation?
What is the primary reason for adjusting the pH of the vehicle in drug formulation?
Which statement about the dissociation constant (pKa) is true?
Which statement about the dissociation constant (pKa) is true?
Which statement about deliquescent powders is true?
Which statement about deliquescent powders is true?
Why is it important to weigh hygroscopic or deliquescent powders quickly?
Why is it important to weigh hygroscopic or deliquescent powders quickly?
In what type of containers should solvates and hydrates be packaged?
In what type of containers should solvates and hydrates be packaged?
Why are many drugs used as their 'salts'?
Why are many drugs used as their 'salts'?
What defines the portion of a drug in solution that will be absorbed for systemic effect?
What defines the portion of a drug in solution that will be absorbed for systemic effect?
Why is it recommended to store all chemicals in 'tight' containers?
Why is it recommended to store all chemicals in 'tight' containers?
What happens when a hygroscopic powder absorbs moisture from the air during weighing?
What happens when a hygroscopic powder absorbs moisture from the air during weighing?
How many pilot-scale batches of the drug substance should be manufactured for data collection?
How many pilot-scale batches of the drug substance should be manufactured for data collection?
What should the packaging for the drug substance stability studies simulate?
What should the packaging for the drug substance stability studies simulate?
How many batches of the manufactured dosage form should be included in the stability studies?
How many batches of the manufactured dosage form should be included in the stability studies?
Which of the following attributes should NOT be tested during the stability studies?
Which of the following attributes should NOT be tested during the stability studies?
What type of products may require separate protocols for stability studies?
What type of products may require separate protocols for stability studies?
What is an example of a functionality test mentioned in the text?
What is an example of a functionality test mentioned in the text?
Which of the following sulfite agents is NOT covered by the FDA regulations?
Which of the following sulfite agents is NOT covered by the FDA regulations?
Why does the FDA permit the use of sulfites in prescription products?
Why does the FDA permit the use of sulfites in prescription products?
What is the purpose of using an inert gas like nitrogen to replace the air in the packaging of oxygen-sensitive drugs?
What is the purpose of using an inert gas like nitrogen to replace the air in the packaging of oxygen-sensitive drugs?
What is the purpose of using antioxidants in certain pharmaceutical preparations?
What is the purpose of using antioxidants in certain pharmaceutical preparations?
What can happen if certain antioxidants are used in pharmaceutical preparations?
What can happen if certain antioxidants are used in pharmaceutical preparations?
Which of the following is NOT a reason why oxygen may be a concern in the storage and preparation of certain pharmaceutical products?
Which of the following is NOT a reason why oxygen may be a concern in the storage and preparation of certain pharmaceutical products?
