Factors Contributing to Increased Risk of Adverse Drug Reactions in Older Adults

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Why does polypharmacy increase the risk of adverse drug reactions (ADRs) in older adults?

It increases the probability of adverse effects and drug-related complications

How can age-related changes in drug metabolism affect older adults' sensitivity to medications?

They may make drugs considered safe in younger populations riskier for older individuals

Why can comorbidities complicate medication management in older adults?

Certain diseases may require medications that interact unfavorably with drugs prescribed for other conditions

How does age-related decline in renal function impact drug clearance?

It may necessitate dosage adjustments or avoidance of certain medications to prevent toxicity

What impact can age-related changes in liver function have on drug metabolism and clearance?

They can impact drug metabolism and clearance processes

Learn about the various factors that contribute to the higher risk of adverse drug reactions (ADRs) in older adults, including polypharmacy and drug sensitivity. Understand how these factors can lead to drug-drug interactions, adverse effects, nonadherence, and complications.

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