Factors Contributing to Increased Risk of Adverse Drug Reactions in Older Adults
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Questions and Answers

Why does polypharmacy increase the risk of adverse drug reactions (ADRs) in older adults?

  • It improves drug metabolism and excretion in older adults
  • It reduces the likelihood of drug-drug interactions
  • It increases the probability of adverse effects and drug-related complications (correct)
  • It decreases the chances of medication nonadherence

    • How can age-related changes in drug metabolism affect older adults' sensitivity to medications?

  • They reduce the need for dosage adjustments in older adults
  • They may make drugs considered safe in younger populations riskier for older individuals (correct)
  • They decrease sensitivity to medications
  • They have no impact on medication sensitivity

    • Why can comorbidities complicate medication management in older adults?

  • Certain diseases may require medications that interact unfavorably with drugs prescribed for other conditions (correct)
  • Comorbidities may lead to less drug interactions
  • Comorbidities reduce the need for multiple medications
  • Having comorbidities reduces the risk of adverse drug reactions

    • How does age-related decline in renal function impact drug clearance?

    <p>It may necessitate dosage adjustments or avoidance of certain medications to prevent toxicity</p> Signup and view all the answers

    What impact can age-related changes in liver function have on drug metabolism and clearance?

    <p>They can impact drug metabolism and clearance processes</p> Signup and view all the answers

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