Exploring Signal Transduction Pathways
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Questions and Answers

Which of the following is NOT considered a chemical messenger in cellular communication?

  • Ions
  • Light (correct)
  • Odorants
  • Steroid hormones

What is the role of cell surface receptors in cellular communication?

  • Diffuse across the plasma membrane
  • Receive and process external signals (correct)
  • Transduce hydrophobic messengers
  • Trigger secondary events

Which of the following is an example of a hydrophobic messenger in cellular communication?

  • Growth factors
  • Steroid hormones (correct)
  • Ions
  • Odorants

What is the purpose of intracellular signaling pathways in cellular communication?

<p>Ensure tight control of cell response (D)</p> Signup and view all the answers

Which of the following is a mechanism by which cells can directly communicate?

<p>Interaction of a receptor with a ligand (B)</p> Signup and view all the answers

What is the function of second messengers in cell signaling?

<p>To amplify signals (A)</p> Signup and view all the answers

Which of the following is an example of a second messenger cascade?

<p>Increased intracellular concentration of cAMP (B)</p> Signup and view all the answers

How do ligands that activate the same signaling pathways in cells usually produce the same effect?

<p>By interacting with distinct receptors (B)</p> Signup and view all the answers

Which of the following is NOT one of the three ways intercellular communication can occur?

<p>Intracrine (D)</p> Signup and view all the answers

What is the role of acetylcholinesterase in paracrine signaling at the neuromuscular junction?

<p>It degrades the neurotransmitter acetylcholine (C)</p> Signup and view all the answers

Which of the following is NOT a type of extracellular signaling molecule?

<p>Nucleotides (A)</p> Signup and view all the answers

What are effectors in signal transduction?

<p>Proteins that initiate a cellular response (B)</p> Signup and view all the answers

Which type of receptor is involved in signaling between electrically excitable cells and results in transient opening of the channel when a neurotransmitter binds to it?

<p>Ligand-gated ion channels (D)</p> Signup and view all the answers

Which type of receptor works indirectly through an intermediary called a G protein to activate or inactivate a separate membrane-associated enzyme or channel?

<p>G protein-coupled receptors (B)</p> Signup and view all the answers

Which type of receptor, when activated by a ligand, can either be enzymes themselves or part of an enzymatic complex?

<p>Catalytic receptors (C)</p> Signup and view all the answers

Which type of receptor, located in the cytosol or nucleus, is ligand-activated and links extracellular signals to gene transcription?

<p>Nuclear receptors (C)</p> Signup and view all the answers

Which of the following is NOT a consequence of ligand binding to a receptor?

<p>Inhibition of protein kinases (D)</p> Signup and view all the answers

What is the role of gap junctions in cell-to-cell communication?

<p>Facilitate the passage of inorganic ions and small molecules (D)</p> Signup and view all the answers

Which of the following is true about adhering junctions?

<p>They provide important clues for the maintenance of normal cell architecture (C)</p> Signup and view all the answers

What is the role of tight junctions in the diffusion barrier?

<p>They stabilize the complex and have a signaling role (A)</p> Signup and view all the answers

Which of the following is a characteristic of ligand-gated ion channels?

<p>They are activated by binding of the signaling molecule to the receptor (A)</p> Signup and view all the answers

What is the function of G proteins in signal transduction?

<p>They mediate cellular responses to a diverse array of signaling molecules (C)</p> Signup and view all the answers

What is the structure of G protein-coupled receptors (GPCRs)?

<p>They consist of a single polypeptide chain with seven membrane-spanning α-helical segments (D)</p> Signup and view all the answers

Which of the following is a characteristic of heterotrimeric G proteins?

<p>They interact with downstream effector proteins such as adenylyl cyclase (A)</p> Signup and view all the answers

Which subunits of the βγ complex are involved in anchoring the complex to the membrane?

<p>α and γ (D)</p> Signup and view all the answers

What holds the α subunit to the membrane?

<p>A myristyl or a palmitoyl group (C)</p> Signup and view all the answers

What holds the γ subunit to the membrane?

<p>A prenyl group (A)</p> Signup and view all the answers

How many combinations of the known α, β, and γ subunits are there?

<p>Several hundred (D)</p> Signup and view all the answers

What do G proteins link together?

<p>Receptors and effectors (C)</p> Signup and view all the answers

What are the multiple classes of G proteins suited for?

<p>Linking receptors to effectors (A)</p> Signup and view all the answers

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