Exogenous Hormones in the cow
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Exogenous Hormones in the cow

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Questions and Answers

Which hormone can control both follicular and luteal function directly?

LH

Which hormone can control hypothalamus function?

Progesterone

Which hormone is required for PGF2A to act?

Progesterone

Which hormone is required for LH to trigger ovulation?

<p>GnRH</p> Signup and view all the answers

Which class of reproductive drugs includes Buserelin and Deslorelin?

<p>GnRH agonists</p> Signup and view all the answers

Which hormone is an example of a sex steroid?

<p>Oestrogens</p> Signup and view all the answers

Which hormone is an example of a prostaglandin?

<p>Dinoprost</p> Signup and view all the answers

Which class of reproductive drugs includes hCG and eCG?

<p>Gonadotrophin</p> Signup and view all the answers

Which hormone is an example of a prolactin inhibitor?

<p>Cabergoline</p> Signup and view all the answers

Which hormone can be used to hasten ovulation by inducing an LH surge?

<p>GnRH</p> Signup and view all the answers

What is the main clinical use of exogenous progestogens?

<p>To prevent oestrus</p> Signup and view all the answers

Which hormone stimulates antral follicular growth?

<p>FSH</p> Signup and view all the answers

What is the long-term action of deslorelin implant, a form of GnRH?

<p>It suppresses the HPG axis</p> Signup and view all the answers

Which hormone is used to force ovulation when there has been repeated failure of conception in cattle?

<p>LH</p> Signup and view all the answers

What is the main effect of progesterone on the hypothalamus/pituitary?

<p>It suppresses the HPG axis</p> Signup and view all the answers

What is the main clinical use of LH hormone?

<p>To induce ovulation</p> Signup and view all the answers

What is the main clinical use of FSH hormone?

<p>To stimulate follicle growth</p> Signup and view all the answers

What is the main clinical use of exogenous progestogens in male dogs?

<p>To stimulate testosterone production</p> Signup and view all the answers

What is the main clinical use of GnRH hormone?

<p>To induce ovulation</p> Signup and view all the answers

Which drug is used for the prevention of oestrus in dogs and the suppression of oestrus?

<p>Megestrol</p> Signup and view all the answers

Which drug is used for oestrus suppression, induction, and synchronization in mares and sows?

<p>Altrenogest</p> Signup and view all the answers

What is the only licensed use of Aglepristone (Alizin)?

<p>Termination of pregnancy in dogs</p> Signup and view all the answers

Which sex steroid is used for the control of urinary incontinence in bitches?

<p>Oestrogens</p> Signup and view all the answers

Which hormone supports the function of the corpus luteum (CL) in bitches and pregnant queens?

<p>Prolactin</p> Signup and view all the answers

Which drug is used to reduce milk production and behavior of pseudopregnancy?

<p>Cabergoline</p> Signup and view all the answers

What is the primary use of melatonin in short-day breeders?

<p>Brings on cyclicity and oestrus</p> Signup and view all the answers

What is the primary use of oxytocin in veterinary medicine?

<p>Facilitating parturition</p> Signup and view all the answers

What is the primary use of prolactin inhibitors in veterinary medicine?

<p>Reducing milk production</p> Signup and view all the answers

What are the two ways in which ovarian and uterine function can be controlled directly?

<p>FSH and LH</p> Signup and view all the answers

What are the two ways in which ovarian and uterine function can be controlled indirectly?

<p>LH and PG2A</p> Signup and view all the answers

What are the two structures that need to be present for PGF2A to act?

<p>Active CL</p> Signup and view all the answers

What is the main hormone required for GnRH/LH to trigger ovulation?

<p>Dominant (large) follicle</p> Signup and view all the answers

What is the main hormone required for FSH to recruit multiple dominant follicles?

<p>Growing antral follicle</p> Signup and view all the answers

What is the main use of aglepristone (Alizin) in veterinary medicine?

<p>termination of pregnancy in the dog</p> Signup and view all the answers

What are the main clinical uses of prostaglandin F2α in veterinary medicine?

<p>termination of luteal phase to synchronize oestrus, induction of abortion, induction of parturition, treatment of chronic metritis, treatment of pyometra (if CL is present)</p> Signup and view all the answers

What is the primary mechanism of action of prolactin inhibitors (e.g. cabergoline [Galastop]) in veterinary medicine?

<p>removal of support for CLs, causing termination of luteal phase and decline in progesterone</p> Signup and view all the answers

What are the potential uses of melatonin in veterinary medicine?

<p>bring on cyclicity/oestrus in ewe, suppress cyclicity/oestrus in mare/cat/ferret, bring on oestrus in mare/cat/ferret</p> Signup and view all the answers

What is the main clinical use of oxytocin in veterinary medicine?

<p>initiation of strong, regular and purposeful contractions of uterine muscle to facilitate parturition, promotion of involution of post-parturient uterus, aid in passage of retained placenta, promotion of milk let-down in agalactia</p> Signup and view all the answers

What are the short-term actions of Gonadotrophin releasing hormone (GnRH)?

<p>Short-term actions of GnRH include hastening impending cyclicity/oestrus, hastening ovulation by inducing LH surge, 'forcing' ovulation/luteinisation of cystic structures, and testing the hypothalamic-gonadal axis.</p> Signup and view all the answers

What are the long-term actions of GnRH (deslorelin implant)?

<p>Long-term actions of GnRH (deslorelin implant) include initial stimulation and then down-regulation of GnRH receptor, thus suppressing the HPG axis. It is used to control behavior and fertility in male dogs and to control/suppress oestrus behavior. It is also used in humans in IVF protocols.</p> Signup and view all the answers

What is the clinical use of FSH hormone?

<p>The clinical use of FSH hormone includes stimulating antral follicular growth, which allows for high selectivity and multiple dominant follicles. It is used as part of oestrus/ovulation induction regimes, often given in conjunction with progestogens.</p> Signup and view all the answers

What is the clinical use of LH hormone?

<p>The clinical use of LH hormone includes stimulating the final maturation of follicles, luteinisation, and providing luteal support. It is used to induce ovulation when animals are in oestrus, hasten ovulation in AI regimes, force ovulation when there has been repeated failure of conception in cattle, and treat cystic ovaries in cows and heifers.</p> Signup and view all the answers

What is the main clinical use of exogenous progestogens?

<p>The main clinical use of exogenous progestogens is to suppress the hypothalamic-gonadal axis, prevent oestrus in dogs and mares, treat and prevent pseudopregnancy in dogs, and treat male conditions like unwanted behavior/prostatic disease. They are also used as a method of inducing/synchronizing oestrus by administration and withdrawal of the product.</p> Signup and view all the answers

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