Exenatide Overview and Dosing Information
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Questions and Answers

What is the brand name for Exenatide?

  • Liraglutide
  • Metformin
  • Byetta (correct)
  • Sitagliptin

Which of the following is a generic name for Byetta?

  • Glimepiride
  • Exenatide (correct)
  • Insulin
  • Acarbose

What are the indications for Exenatide?

Type 2 Diabetes

What is the immediate release dosing for Exenatide?

<p>5-10 mcg sq bid</p> Signup and view all the answers

What is the extended release dosing for Exenatide?

<p>2 mg sq weekly</p> Signup and view all the answers

What are the strengths of Exenatide available for injection?

<p>5 mcg/0.02 ml and 10 mcg/0.05 ml; 2 mg</p> Signup and view all the answers

What class of medication does Exenatide belong to?

<p>Glucagon-Like Peptide-1 Receptor Agonist (GLP-1 R Agonist)</p> Signup and view all the answers

What is the pharmacological mechanism of action (MOA) of Exenatide?

<p>Increases insulin secretion and decreases glucagon secretion</p> Signup and view all the answers

Which drug interactions are associated with Exenatide?

<p>Warfarin (increased risk of bleeding)</p> Signup and view all the answers

What are some common side effects of Exenatide?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is a contraindication for Exenatide?

<p>Renal Insufficiency (B)</p> Signup and view all the answers

What is a key point of patient counseling regarding Exenatide?

<p>Use 1 hr before eating and store properly</p> Signup and view all the answers

What should patients monitor while on Exenatide?

<p>Glucose levels</p> Signup and view all the answers

Study Notes

Exenatide Overview

  • Brand name: Byetta
  • Generic name: Exenatide
  • Primary indication: Treatment of Type 2 Diabetes

Dosing Information

  • Immediate release: Administer 5-10 mcg subcutaneously twice daily
  • Extended release: Administer 2 mg subcutaneously once weekly

Available Forms and Strengths

  • Subcutaneous solution for injection: Available in strengths of 5 mcg/0.02 ml and 10 mcg/0.05 ml
  • Subcutaneous suspension for injection: Available in a strength of 2 mg

Medication Classification

  • Class: Glucagon-Like Peptide-1 Receptor Agonist (GLP-1 R Agonist)

Pharmacology and Mechanism of Action

  • Exenatide acts as a GLP-1 mimetic, enhancing insulin secretion while inhibiting glucagon secretion

Drug Interactions

  • Notable interaction with Warfarin, which may increase the risk of bleeding

Side Effects and Adverse Reactions

  • Common side effects include:
    • Hypoglycemia
    • Diarrhea
    • Nausea

Contraindications

  • Avoid use in patients with:
    • Hypersensitivity to exenatide
    • Renal insufficiency

Patient Counseling and Storage

  • Instruct patients to use 1 hour before meals
  • Store unused medication in the refrigerator; can be kept at room temperature during use
  • Discard used pens after 30 days
  • Emphasize the importance of monitoring glucose levels regularly
  • Advise carrying candy for emergencies due to potential hypoglycemia

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Description

This quiz covers essential details about Exenatide, including its classification as a GLP-1 receptor agonist and its role in treating Type 2 Diabetes. You'll also learn about dosing guidelines, available forms, potential drug interactions, side effects, and contraindications. Test your knowledge and understanding of this important medication!

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