Exenatide Overview and Dosing Information
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Questions and Answers

What is the brand name for Exenatide?

  • Liraglutide
  • Metformin
  • Byetta (correct)
  • Sitagliptin

    • Which of the following is a generic name for Byetta?

  • Glimepiride
  • Exenatide (correct)
  • Insulin
  • Acarbose

    • What are the indications for Exenatide?

    Type 2 Diabetes

    What is the immediate release dosing for Exenatide?

    <p>5-10 mcg sq bid</p> Signup and view all the answers

    What is the extended release dosing for Exenatide?

    <p>2 mg sq weekly</p> Signup and view all the answers

    What are the strengths of Exenatide available for injection?

    <p>5 mcg/0.02 ml and 10 mcg/0.05 ml; 2 mg</p> Signup and view all the answers

    What class of medication does Exenatide belong to?

    <p>Glucagon-Like Peptide-1 Receptor Agonist (GLP-1 R Agonist)</p> Signup and view all the answers

    What is the pharmacological mechanism of action (MOA) of Exenatide?

    <p>Increases insulin secretion and decreases glucagon secretion</p> Signup and view all the answers

    Which drug interactions are associated with Exenatide?

    <p>Warfarin (increased risk of bleeding)</p> Signup and view all the answers

    What are some common side effects of Exenatide?

    <p>All of the above</p> Signup and view all the answers

    Which of the following is a contraindication for Exenatide?

    <p>Renal Insufficiency</p> Signup and view all the answers

    What is a key point of patient counseling regarding Exenatide?

    <p>Use 1 hr before eating and store properly</p> Signup and view all the answers

    What should patients monitor while on Exenatide?

    <p>Glucose levels</p> Signup and view all the answers

    Study Notes

    Exenatide Overview

    • Brand name: Byetta
    • Generic name: Exenatide
    • Primary indication: Treatment of Type 2 Diabetes

    Dosing Information

    • Immediate release: Administer 5-10 mcg subcutaneously twice daily
    • Extended release: Administer 2 mg subcutaneously once weekly

    Available Forms and Strengths

    • Subcutaneous solution for injection: Available in strengths of 5 mcg/0.02 ml and 10 mcg/0.05 ml
    • Subcutaneous suspension for injection: Available in a strength of 2 mg

    Medication Classification

    • Class: Glucagon-Like Peptide-1 Receptor Agonist (GLP-1 R Agonist)

    Pharmacology and Mechanism of Action

    • Exenatide acts as a GLP-1 mimetic, enhancing insulin secretion while inhibiting glucagon secretion

    Drug Interactions

    • Notable interaction with Warfarin, which may increase the risk of bleeding

    Side Effects and Adverse Reactions

    • Common side effects include:
      • Hypoglycemia
      • Diarrhea
      • Nausea

    Contraindications

    • Avoid use in patients with:
      • Hypersensitivity to exenatide
      • Renal insufficiency

    Patient Counseling and Storage

    • Instruct patients to use 1 hour before meals
    • Store unused medication in the refrigerator; can be kept at room temperature during use
    • Discard used pens after 30 days
    • Emphasize the importance of monitoring glucose levels regularly
    • Advise carrying candy for emergencies due to potential hypoglycemia

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    Description

    This quiz covers essential details about Exenatide, including its classification as a GLP-1 receptor agonist and its role in treating Type 2 Diabetes. You'll also learn about dosing guidelines, available forms, potential drug interactions, side effects, and contraindications. Test your knowledge and understanding of this important medication!

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