Excretory System Overview and Kidney Function

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Questions and Answers

What are the three main parts of the kidney, and what is the function of each part?

The three main parts of the kidney are the cortex, medulla, and pelvis. The cortex contains nephrons which filter blood. The medulla contains the loops of Henle and collecting ducts which concentrate urine. The pelvis collects and drains urine into the ureter.

What are the three main steps involved in urine formation? Briefly describe each step.

Urine formation involves three steps: filtration, reabsorption, and secretion. Filtration occurs in the glomerulus, where blood is filtered and primary urine is formed. Reabsorption occurs in the proximal convoluted tubule, where essential substances are reabsorbed back into the blood. Secretion occurs in the distal convoluted tubule and collecting ducts, where final adjustments to the urine composition are made.

What is the difference between albuminuria and hematuria? How do these conditions indicate kidney damage?

Albuminuria is the presence of protein in urine, while hematuria is the presence of blood in urine. Both conditions indicate kidney damage because healthy kidneys should not allow these substances to pass into the filtrate.

Why is the presence of glucose in urine a potential indicator of diabetes mellitus?

<p>Glucose is normally reabsorbed in the proximal convoluted tubule during urine formation. In diabetes mellitus, blood glucose levels are high, and the kidneys may not be able to reabsorb all of it, leading to glucose being excreted in the urine.</p> Signup and view all the answers

Explain the role of the loop of Henle and collecting ducts in concentrating urine.

<p>The loop of Henle and collecting ducts create a concentration gradient in the medulla, causing water to be reabsorbed from the urine, concentrating it. This process is essential for maintaining water balance in the body.</p> Signup and view all the answers

What is uremia? What are its causes, and how is it treated?

<p>Uremia is a condition characterized by high levels of non-protein nitrogen waste products in the blood. It is caused by kidney failure, where the kidneys are unable to effectively filter these wastes. Treatment options include hemodialysis, which filters the blood outside of the body.</p> Signup and view all the answers

What is renal failure, and what are the potential outcomes?

<p>Renal failure is a condition where the kidneys stop functioning properly. This can range from mild to severe, with severe cases requiring a kidney transplant to survive.</p> Signup and view all the answers

What are renal calculi (kidney stones), and what are their potential complications?

<p>Renal calculi are solid crystals that form in the kidneys. They can block the flow of urine, causing pain and potentially leading to infection or kidney damage.</p> Signup and view all the answers

What is glomerulonephritis, and what are its causes?

<p>Glomerulonephritis is an inflammation of the glomerulus. It is caused by damage to the glomerulus, which can be caused by infections, autoimmune diseases, or other factors.</p> Signup and view all the answers

Why is excretion crucial for maintaining the body's health?

<p>Excretion is essential for removing waste products from the body, maintaining the balance of water and electrolytes, and preventing the accumulation of toxins that could harm bodily functions.</p> Signup and view all the answers

Flashcards

Excretory System

Removes metabolic waste from the body.

Nephrons

Functional units of the kidney, about one million per kidney.

Glomerulus

Cluster of capillaries in the nephron that filters blood.

Bowman’s Capsule

Surrounds the glomerulus and collects filtered substances.

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Filtration

First step of urine formation; small molecules filter into Bowman’s Capsule.

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Albuminuria

Presence of protein in urine, indicates kidney damage.

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Reabsorption

Process in the proximal convoluted tubule where essential substances are reabsorbed.

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Uremia

High levels of non-protein nitrogen in blood; can be treated with hemodialysis.

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Renal Calculi

Formation of solid crystals in the kidney, known as kidney stones.

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Glomerulonephritis

Inflammation of the glomerulus due to leakage of protein or RBCs.

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Study Notes

Excretory System Overview

  • The excretory system eliminates metabolic waste from the body.
  • It differs from defecation (removing undigested food) and secretion (releasing useful substances).
  • Key organs include kidneys, lungs, liver, and skin.

Kidney Structure and Function

  • The kidney has three main parts: cortex, medulla, and pelvis.
  • The cortex contains nephrons, the kidney's functional units.
  • Nephrons consist of glomerulus (filters blood), Bowman's capsule (collects filtrate), and renal tubules (reabsorb/filter).
  • The medulla contains Henle's loop and collecting ducts (concentrate urine).
  • The pelvis collects and drains urine to the ureter.

Urine Formation

  • Urine formation involves three stages: filtration, reabsorption, and augmentation.
  • Filtration: Blood passes through glomerulus, filtering small molecules into Bowman's capsule (primary urine).
    • Albuminuria = Protein in urine (kidney damage).
    • Hematuria = Blood in urine (glomerular damage).
  • Reabsorption: Essential substances (glucose, amino acids, ions, water) are reabsorbed into the blood, mainly in the proximal convoluted tubule.
    • Glucose in urine suggests diabetes mellitus.
  • Augmentation: Distal convoluted tubule and collecting ducts adjust water, salts, and urea to form urine.
    • Urine consists of urea, uric acid, ammonia, creatinine and other waste. Urine travels from ureter to bladder to urethra for excretion.

Excretory Disorders

  • Uremia: High levels of nitrogenous waste in blood (treated with hemodialysis).
  • Renal failure: Kidney malfunction (severe cases need transplants).
  • Renal calculi (kidney stones): solid crystals in kidney.
  • Glomerulonephritis (Bright's disease): glomerulus inflammation from protein/RBC leakage.

Other Excretory Organs

  • Lungs: Remove carbon dioxide and water vapor via exhalation.
  • Liver: Processes waste (e.g., converts ammonia to urea) and breaks down toxins.
  • Skin: Removes waste through sweat; regulates body temperature.

Skin as a Sensory Organ

  • The skin detects sensations, including:
    • Cold (Krause's corpuscles)
    • Heat (Ruffini's corpuscles)
    • Pressure (Pacinian corpuscles)
    • Touch (Meissner's corpuscles)
    • Pain (free nerve endings)

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