Evolutionary Mismatch: Novel Environments and Disease
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Questions and Answers

According to Nesse and Williams, what are the categories of evolutionary explanations of disease?

  • Seven categories
  • Four categories and two exceptions
  • Five categories and one exception
  • Six categories (correct)

What is the difference between a defect and a defense in relation to disease?

  • A defect is a intentional response, whereas a defense is a unintentional response
  • A defect is a chronic condition, whereas a defense is an acute condition
  • A defect is a happenstance result with no particular utility, whereas a defense is a deliberate response (correct)
  • A defect is a harmful response, whereas a defense is a helpful response

Why do humans still get diseases despite the body's sophisticated design?

  • The body is a bundle of careful compromises (correct)
  • Natural selection is not powerful enough
  • Humans are not adapted to modern environments
  • Diseases are a result of random mutations

What is the significance of a fair-skinned person's skin turning blue when they have pneumonia?

<p>It's a result of the body's attempt to compensate for lack of oxygen (A)</p> Signup and view all the answers

Why can't humans grow a replacement for a damaged finger?

<p>The body's design is a bundle of careful compromises (D)</p> Signup and view all the answers

What is a possible explanation for why humans can't live to be 200 years old?

<p>The body is a bundle of careful compromises (C)</p> Signup and view all the answers

What is the primary reason why certain genes that cause disease have been selected for?

<p>They provide a benefit to the bearer or others with the gene in a different combination (D)</p> Signup and view all the answers

What is the benefit of the gene that causes sickle-cell?

<p>It prevents malaria (C)</p> Signup and view all the answers

What is an example of an evolutionary trade-off in human evolution?

<p>The ability to walk upright (A)</p> Signup and view all the answers

Why are many of the body’s apparent design flaws not considered mistakes?

<p>They are compromises to achieve a greater advantage (C)</p> Signup and view all the answers

What is necessary to better understand disease?

<p>To understand the hidden benefits of apparent mistakes in design (B)</p> Signup and view all the answers

What is an example of a sexually antagonistic gene?

<p>A gene that benefits fathers at the expense of mothers (C)</p> Signup and view all the answers

What is the main reason for the development of most preventable modern diseases?

<p>Due to the mismatch between our bodies and modern environments (D)</p> Signup and view all the answers

What is an example of a novel environment that contributes to the development of a disease?

<p>Migration to a new geographic location (A)</p> Signup and view all the answers

Why do some genes that cause disease persist in the population?

<p>Because natural selection has not had time to remove them (A)</p> Signup and view all the answers

What is an example of a gene that was harmless in our natural environment but causes problems in modern environments?

<p>A gene that causes nearsightedness (C)</p> Signup and view all the answers

What is an example of how lifestyle changes can contribute to the development of disease?

<p>Increased caloric availability (C)</p> Signup and view all the answers

What is an example of a novel environment that can disrupt natural circadian rhythms?

<p>Exposure to artificial light at night (A)</p> Signup and view all the answers

What is a limitation of evolutionary change?

<p>It can only make small changes that are immediately beneficial (C)</p> Signup and view all the answers

Why would relocating the nostrils to the neck not be a viable solution?

<p>It would require a major redesign of the respiratory system (C)</p> Signup and view all the answers

What is the main advantage of the mouse's ability to detect cat odor?

<p>It enables the mouse to avoid predators more effectively (C)</p> Signup and view all the answers

Why should the doctor not prescribe the drug to dull the sense of smell in mice?

<p>It would reduce the mice's ability to detect predators (A)</p> Signup and view all the answers

What is the primary concern for pediatricians treating children with colds?

<p>Mitigating the unpleasant symptoms of the cold (C)</p> Signup and view all the answers

What is a key aspect of the relationship between disease and natural selection?

<p>Diseases can drive the evolution of defense mechanisms (B)</p> Signup and view all the answers

What is the primary function of the cough defense mechanism?

<p>To expel mucus and foreign matter from the respiratory tract (B)</p> Signup and view all the answers

What is the consequence of eliminating a defense mechanism in the body?

<p>It can be catastrophic (B)</p> Signup and view all the answers

What is the nature of the relationship between humans and pathogens, such as bacteria and viruses?

<p>An endless arms race (C)</p> Signup and view all the answers

Why is it impossible to eradicate all infections?

<p>Because of the continuous evolution of pathogens (B)</p> Signup and view all the answers

What is the primary difference between a defect and a defense in relation to disease?

<p>A defect is a malfunction, while a defense is a protective response (D)</p> Signup and view all the answers

What is the significance of natural selection in the context of disease?

<p>It shapes the body's defenses against pathogens (A)</p> Signup and view all the answers

What is the primary function of fever in response to infection?

<p>To combat infection and eliminate pathogens (B)</p> Signup and view all the answers

What happens when cold-blooded lizards are infected and cannot move to a warm place?

<p>They are more likely to die (B)</p> Signup and view all the answers

Why does Matt Kluger believe that using drugs to suppress fever can be harmful?

<p>Because fever can make people sicker and even die (A)</p> Signup and view all the answers

What is the significance of the lizard's ability to raise its body temperature?

<p>It helps the lizard to combat infection (D)</p> Signup and view all the answers

What is the role of body temperature in infection?

<p>It is carefully regulated to combat infection (C)</p> Signup and view all the answers

What is the consequence of suppressing fever with drugs, according to Matt Kluger?

<p>People are more likely to die (D)</p> Signup and view all the answers

What is an example of an adaptive host response to infection?

<p>Fever (C)</p> Signup and view all the answers

What happens to the lizard's body temperature when it is infected?

<p>It rises (A)</p> Signup and view all the answers

What is the significance of fever in the context of disease and evolution?

<p>It is a defense mechanism against infection (D)</p> Signup and view all the answers

What is the relationship between fever and infection?

<p>Fever is a response to infection (A)</p> Signup and view all the answers

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