Podcast
Questions and Answers
Telomeres are found at the ______ ends of chromosomes
Telomeres are found at the ______ ends of chromosomes
linear
Telomeres protect DNA from damage by ______
Telomeres protect DNA from damage by ______
nucleases
Telomeres distinguish the end of a chromosome from a ______ break
Telomeres distinguish the end of a chromosome from a ______ break
double-stranded
Telomeres shorten with each successive ______ division
Telomeres shorten with each successive ______ division
High telomerase activity is a characteristic of ______ cells
High telomerase activity is a characteristic of ______ cells
There are over 200 genes involved in ______ repair
There are over 200 genes involved in ______ repair
Xeroderma pigmentosum is a rare genetic disease caused by defects in ______ genes
Xeroderma pigmentosum is a rare genetic disease caused by defects in ______ genes
DNA strands are composed of bases along a ______ backbone
DNA strands are composed of bases along a ______ backbone
The backbones run in ______ directions - antiparallel
The backbones run in ______ directions - antiparallel
DNA is read along the ______ (5′ → 3′)
DNA is read along the ______ (5′ → 3′)
DNA is ______ charged
DNA is ______ charged
Complimentary bases held together via ______ bond
Complimentary bases held together via ______ bond
Each nucleotide in the chain is connected via a ______ bond
Each nucleotide in the chain is connected via a ______ bond
During storage, DNA wraps around ______ proteins
During storage, DNA wraps around ______ proteins
DNA polymerase reads the parental template strand in the ______ direction
DNA polymerase reads the parental template strand in the ______ direction
The precursors for replication are ______
The precursors for replication are ______
As DNA synthesis proceeds in the ______ direction, one parental strand is synthesized continuously
As DNA synthesis proceeds in the ______ direction, one parental strand is synthesized continuously
The other parental strand exhibits ______ synthesis
The other parental strand exhibits ______ synthesis
Small fragments named ______ are created during discontinuous synthesis
Small fragments named ______ are created during discontinuous synthesis
DNA polymerase can only synthesize DNA in the ______ direction
DNA polymerase can only synthesize DNA in the ______ direction
DNA polymerase requires a free ______ group of a nucleotide primer
DNA polymerase requires a free ______ group of a nucleotide primer
The primer is synthesized by the enzyme ______
The primer is synthesized by the enzyme ______
The enzyme ______ synthesizes the ends of linear chromosomes (telomeres)
The enzyme ______ synthesizes the ends of linear chromosomes (telomeres)
The DnaA protein binds to the DnaA Box within the Ori to initiate replication.
The DnaA protein binds to the DnaA Box within the Ori to initiate replication.
The DNA Helicase enzyme binds to ssDNA at the Ori to force the strands apart and unwinds the double helix.
The DNA Helicase enzyme binds to ssDNA at the Ori to force the strands apart and unwinds the double helix.
The Single-stranded Binding (SSB) proteins bind to the ssDNA created by Helicase to keep the strands separated in the replication bubble and protect DNA from nucleases that degrade ssDNA.
The Single-stranded Binding (SSB) proteins bind to the ssDNA created by Helicase to keep the strands separated in the replication bubble and protect DNA from nucleases that degrade ssDNA.
Topoisomerase I cuts one strand, rotates it around an intact strand, and reseals the nick.
Topoisomerase I cuts one strand, rotates it around an intact strand, and reseals the nick.
Topoisomerase II binds tightly to DNA to make a transient break in both strands and passes a
Topoisomerase II binds tightly to DNA to make a transient break in both strands and passes a
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