Esophageal Cancer Clinical Features Quiz

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Which of the following is a pre-malignant lesion that results from metaplasia of esophageal mucosa into gastric or intestinal mucosa?

Esophageal Adenocarcinoma

Barrett's Esophagus (correct)

Squamous Cell Carcinoma of the Esophagus

Reflux Esophagitis

What is the most common symptom associated with Gastroesophageal Reflux Disease (GERD)?

Heartburn (correct)

Melena

Hematemesis

Dysphagia

Which of the following is a feature of Barrett's Esophagus?

Mutation of tumor suppressor genes

Presence of goblet cells (correct)

Inflammation of squamous mucosa

Activation of oncogenes

What may occur as a consequence of recurrent and persistent reflux in GERD?

Inflammation Signup and view all the answers

Which factor does NOT predispose individuals to Gastroesophageal Reflux Disease (GERD)?

Low-fat diet Signup and view all the answers

What type of genetic abnormalities/mutations are typically required for malignant transformation in diseases like esophageal adenocarcinoma?

Accumulative genetic abnormalities/mutations Signup and view all the answers

What is the most common causative agent of gastritis that leads to an increased risk of adenocarcinoma?

H. pylori Signup and view all the answers

Which bacterial enzyme, produced by H. pylori, generates ammonia to protect the bacteria from the acidic environment?

Urease Signup and view all the answers

What is the typical presentation of H. pylori infection in the stomach?

Antral gastritis Signup and view all the answers

Which of the following complications is associated with stress ulcers in ICU patients?

Curling ulcers Signup and view all the answers

What is the common pathological finding in individuals infected with H. pylori?

Lymphoid follicle formation with germinal centers Signup and view all the answers

Which bacterial gene encodes toxins that play a role in the pathogenesis of H. pylori-associated gastritis?

CagA Signup and view all the answers

What is the major risk factor for developing esophageal adenocarcinoma?

Barrett's esophagus Signup and view all the answers

What is the characteristic appearance of the gastroesophageal junction in a patient with Barrett's esophagus?

Red and rough Signup and view all the answers

Which symptom is often associated with both gastroesophageal reflux disease (GERD) and esophageal adenocarcinoma?

Dysphagia Signup and view all the answers

Inflammation of the stomach (gastritis) can be caused by all of the following EXCEPT:

Helicobacter pylori infection Signup and view all the answers

Which of the following protective measures is NOT found in the stomach?

$CO_2$ secretion Signup and view all the answers

What is a common clinical complication associated with Barrett's esophagus?

$Eso$phageal strictures Signup and view all the answers