Esophageal Cancer Clinical Features Quiz
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Questions and Answers

Which of the following is a pre-malignant lesion that results from metaplasia of esophageal mucosa into gastric or intestinal mucosa?

  • Esophageal Adenocarcinoma
  • Barrett's Esophagus (correct)
  • Squamous Cell Carcinoma of the Esophagus
  • Reflux Esophagitis

What is the most common symptom associated with Gastroesophageal Reflux Disease (GERD)?

  • Heartburn (correct)
  • Melena
  • Hematemesis
  • Dysphagia

Which of the following is a feature of Barrett's Esophagus?

  • Mutation of tumor suppressor genes
  • Presence of goblet cells (correct)
  • Inflammation of squamous mucosa
  • Activation of oncogenes

What may occur as a consequence of recurrent and persistent reflux in GERD?

<p>Inflammation (C)</p> Signup and view all the answers

Which factor does NOT predispose individuals to Gastroesophageal Reflux Disease (GERD)?

<p>Low-fat diet (A)</p> Signup and view all the answers

What type of genetic abnormalities/mutations are typically required for malignant transformation in diseases like esophageal adenocarcinoma?

<p>Accumulative genetic abnormalities/mutations (C)</p> Signup and view all the answers

What is the most common causative agent of gastritis that leads to an increased risk of adenocarcinoma?

<p>H. pylori (D)</p> Signup and view all the answers

Which bacterial enzyme, produced by H. pylori, generates ammonia to protect the bacteria from the acidic environment?

<p>Urease (A)</p> Signup and view all the answers

What is the typical presentation of H. pylori infection in the stomach?

<p>Antral gastritis (D)</p> Signup and view all the answers

Which of the following complications is associated with stress ulcers in ICU patients?

<p>Curling ulcers (A)</p> Signup and view all the answers

What is the common pathological finding in individuals infected with H. pylori?

<p>Lymphoid follicle formation with germinal centers (B)</p> Signup and view all the answers

Which bacterial gene encodes toxins that play a role in the pathogenesis of H. pylori-associated gastritis?

<p>CagA (C)</p> Signup and view all the answers

What is the major risk factor for developing esophageal adenocarcinoma?

<p>Barrett's esophagus (C)</p> Signup and view all the answers

What is the characteristic appearance of the gastroesophageal junction in a patient with Barrett's esophagus?

<p>Red and rough (A)</p> Signup and view all the answers

Which symptom is often associated with both gastroesophageal reflux disease (GERD) and esophageal adenocarcinoma?

<p>Dysphagia (B)</p> Signup and view all the answers

Inflammation of the stomach (gastritis) can be caused by all of the following EXCEPT:

<p>Helicobacter pylori infection (A)</p> Signup and view all the answers

Which of the following protective measures is NOT found in the stomach?

<p>$CO_2$ secretion (A)</p> Signup and view all the answers

What is a common clinical complication associated with Barrett's esophagus?

<p>$Eso$phageal strictures (B)</p> Signup and view all the answers

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