Esophageal Cancer Clinical Features Quiz
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Questions and Answers

Which of the following is a pre-malignant lesion that results from metaplasia of esophageal mucosa into gastric or intestinal mucosa?

  • Esophageal Adenocarcinoma
  • Barrett's Esophagus (correct)
  • Squamous Cell Carcinoma of the Esophagus
  • Reflux Esophagitis
  • What is the most common symptom associated with Gastroesophageal Reflux Disease (GERD)?

  • Heartburn (correct)
  • Melena
  • Hematemesis
  • Dysphagia
  • Which of the following is a feature of Barrett's Esophagus?

  • Mutation of tumor suppressor genes
  • Presence of goblet cells (correct)
  • Inflammation of squamous mucosa
  • Activation of oncogenes
  • What may occur as a consequence of recurrent and persistent reflux in GERD?

    <p>Inflammation</p> Signup and view all the answers

    Which factor does NOT predispose individuals to Gastroesophageal Reflux Disease (GERD)?

    <p>Low-fat diet</p> Signup and view all the answers

    What type of genetic abnormalities/mutations are typically required for malignant transformation in diseases like esophageal adenocarcinoma?

    <p>Accumulative genetic abnormalities/mutations</p> Signup and view all the answers

    What is the most common causative agent of gastritis that leads to an increased risk of adenocarcinoma?

    <p>H. pylori</p> Signup and view all the answers

    Which bacterial enzyme, produced by H. pylori, generates ammonia to protect the bacteria from the acidic environment?

    <p>Urease</p> Signup and view all the answers

    What is the typical presentation of H. pylori infection in the stomach?

    <p>Antral gastritis</p> Signup and view all the answers

    Which of the following complications is associated with stress ulcers in ICU patients?

    <p>Curling ulcers</p> Signup and view all the answers

    What is the common pathological finding in individuals infected with H. pylori?

    <p>Lymphoid follicle formation with germinal centers</p> Signup and view all the answers

    Which bacterial gene encodes toxins that play a role in the pathogenesis of H. pylori-associated gastritis?

    <p>CagA</p> Signup and view all the answers

    What is the major risk factor for developing esophageal adenocarcinoma?

    <p>Barrett's esophagus</p> Signup and view all the answers

    What is the characteristic appearance of the gastroesophageal junction in a patient with Barrett's esophagus?

    <p>Red and rough</p> Signup and view all the answers

    Which symptom is often associated with both gastroesophageal reflux disease (GERD) and esophageal adenocarcinoma?

    <p>Dysphagia</p> Signup and view all the answers

    Inflammation of the stomach (gastritis) can be caused by all of the following EXCEPT:

    <p>Helicobacter pylori infection</p> Signup and view all the answers

    Which of the following protective measures is NOT found in the stomach?

    <p>$CO_2$ secretion</p> Signup and view all the answers

    What is a common clinical complication associated with Barrett's esophagus?

    <p>$Eso$phageal strictures</p> Signup and view all the answers

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