Equine Cardiology: Arrhythmias and ECG

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Questions and Answers

In a healthy equine patient, the typical order of auscultation of heart sounds, from the onset of diastole to the end of systole, is best represented by which sequence?

  • S3, S4, S1, S2
  • S4, S1, S2, S3 (correct)
  • S1, S2, S3, S4
  • S2, S1, S4, S3

A veterinary student is learning equine auscultation. To best assess the mitral valve, where should they position their stethoscope?

  • Right side, caudal to the olecranon process
  • Left side, approximately at the 5th intercostal space, at the level of the elbow (correct)
  • Left side, cranial to the triceps brachii muscle
  • Right side, at the level of the 3rd-4th intercostal space

A clinician auscultates a regularly irregular rhythm in a resting Standardbred horse with a heart rate of 32 bpm. Which of the following is the MOST likely physiological explanation for this finding?

  • Atrial fibrillation secondary to increased vagal tone
  • Ventricular premature contractions due to myocardial disease
  • Third-degree AV block requiring immediate intervention
  • Physiologic second-degree atrioventricular (AV) block (correct)

When auscultating a horse, you identify a 'dropped beat' that disappears upon exercise. Which characteristic of the heart sound pattern is MOST consistent with a physiological 2nd degree AV block in this scenario?

<p>Progressive lengthening of the P-R interval before the dropped beat (C)</p> Signup and view all the answers

In equine cardiology, atrial fibrillation is considered an important pathogenic arrhythmia. Which of the following statements accurately reflects a key characteristic differentiating atrial fibrillation from other equine arrhythmias?

<p>Atrial fibrillation is commonly associated with an irregularly irregular rhythm and absence of P waves on ECG. (A)</p> Signup and view all the answers

Differentiating between ventricular tachycardia and supraventricular tachycardia is critical in equine cardiology for prognosis and treatment. What is the MOST reliable ECG characteristic to distinguish ventricular tachycardia from supraventricular tachycardia?

<p>QRS complexes that are wide and bizarre in morphology in ventricular tachycardia. (C)</p> Signup and view all the answers

A 15-year-old Warmblood presents with exercise intolerance. Auscultation reveals a grade 3/6 systolic murmur loudest over the left heart base. Which of the following is the MOST likely underlying cause of this murmur in an older athletic horse?

<p>Mitral valve regurgitation due to degenerative valve disease (C)</p> Signup and view all the answers

Thoracic radiographs are often part of the diagnostic workup for equine cardiac conditions. However, their utility in directly assessing the heart is limited compared to other modalities. What is the PRIMARY information gained from thoracic radiographs in a horse with suspected cardiac disease?

<p>Evaluation of pulmonary vasculature and lung parenchyma for signs of congestive heart failure (B)</p> Signup and view all the answers

Echocardiography is a cornerstone diagnostic tool in equine cardiology. Which of the following best describes the optimal probe frequency range used for equine echocardiography and the rationale behind it?

<p>Low frequency (2-3 MHz) to achieve adequate penetration depth for large equine thorax. (C)</p> Signup and view all the answers

M-mode echocardiography is utilized in equine cardiology to assess specific cardiac parameters. Which of the following BEST describes the primary application of M-mode echocardiography?

<p>Evaluating the movement of cardiac structures over time, particularly for chamber dimension and wall thickness measurements. (B)</p> Signup and view all the answers

Pulsed wave Doppler echocardiography is essential for evaluating blood flow in equine cardiology. What is a key limitation of pulsed wave Doppler compared to continuous wave Doppler?

<p>Pulsed wave Doppler has a limited maximum measurable velocity due to aliasing. (D)</p> Signup and view all the answers

In color flow Doppler echocardiography, different colors are used to represent blood flow direction and velocity. What does the color 'yellow' typically indicate in the context of equine cardiac blood flow mapping?

<p>Aliasing, indicating that the blood flow velocity exceeds the Nyquist limit. (C)</p> Signup and view all the answers

Cardiac Troponin I (cTnI) is increasingly used in equine medicine as a biomarker. Which of the following clinical scenarios would BEST justify the use of cTnI measurement in a horse?

<p>Evaluating myocardial injury in horses suspected of ionophore toxicity. (B)</p> Signup and view all the answers

A client calls your clinic concerned about their horse. They describe the horse as 'not performing as well' and 'tiring easily'. Which of the following historical details would be MOST critical to elicit from the client to assess for potential cardiac involvement in exercise intolerance?

<p>Onset and progression of exercise intolerance, specifically if it's acute or gradual. (D)</p> Signup and view all the answers

A horse presents with acute onset of weakness, ataxia, and episodes of collapse. While colic and neurological conditions are considered, what specific historical or clinical finding would STRONGLY suggest a primary cardiac etiology for these neurological-like signs?

<p>Auscultation of a significant cardiac arrhythmia or marked bradycardia. (C)</p> Signup and view all the answers

A horse diagnosed with third-degree atrioventricular (AV) block is presented for evaluation. What is the IMMEDIATE clinical significance of this arrhythmia in relation to physical examination findings and patient management?

<p>Third-degree AV block indicates complete electrical dissociation between atria and ventricles, often resulting in significantly reduced cardiac output and potential for collapse. (A)</p> Signup and view all the answers

A horse is exhibiting coughing and nasal discharge that appears frothy and blood-tinged. In the context of equine cardiology, what is the MOST concerning interpretation of these respiratory signs?

<p>Pulmonary edema secondary to left-sided heart failure. (D)</p> Signup and view all the answers

Sudden death in horses during exercise is a devastating event. In cases of exercise-related sudden death where necropsy reveals no gross lesions, what is the MOST probable underlying cause?

<p>Fatal cardiac arrhythmia. (D)</p> Signup and view all the answers

During a routine pre-purchase examination of a sport horse, you palpate the facial artery to assess the pulse. Which of the following pulse characteristics is MOST important to evaluate in the context of a cardiovascular assessment?

<p>Pulse rhythm, rate, and strength. (B)</p> Signup and view all the answers

During a physical examination, you observe pronounced jugular venous distention extending high up the neck in a horse at rest with its head in a normal position. This finding is MOST suggestive of:

<p>Increased central venous pressure, potentially due to right-sided heart failure or tricuspid valve disease. (B)</p> Signup and view all the answers

A jugular pulse is normally visible in the distal third of the jugular vein when a horse is standing with its head raised. If the jugular pulse is observed to extend further up the neck, this ABNORMAL finding is MOST likely associated with:

<p>Conditions causing increased right atrial pressure, such as tricuspid valve insufficiency or right ventricular failure. (C)</p> Signup and view all the answers

You are evaluating a horse with cyanotic mucous membranes. This bluish discoloration is primarily caused by an increased concentration of:

<p>Deoxygenated hemoglobin. (B)</p> Signup and view all the answers

While assessing mucous membrane color, you note that a horse's mucous membranes are white. This finding is MOST consistent with which underlying physiological derangement?

<p>Anemia or significant blood loss. (C)</p> Signup and view all the answers

Ventral edema in horses, characterized by fluid accumulation along the ventral abdomen and limbs, is a frequent clinical sign of:

<p>Increased hydrostatic pressure due to heart failure. (A)</p> Signup and view all the answers

During cardiac auscultation, which of the following components is MOST crucial for a comprehensive assessment, beyond just heart rate?

<p>Identification of heart sounds, rhythm, and murmurs. (C)</p> Signup and view all the answers

S1 heart sound is primarily attributed to the closure of which cardiac valves in the equine heart?

<p>Tricuspid and mitral valves. (D)</p> Signup and view all the answers

To auscultate the pulmonic valve area effectively in a horse, where should the stethoscope be optimally placed in relation to anatomical landmarks?

<p>Left side, cranial to the point of the shoulder, approximately 2nd-4th intercostal space. (D)</p> Signup and view all the answers

Cardiac murmurs are indicative of turbulent blood flow. Which of the following factors is LEAST likely to contribute to the generation of a cardiac murmur in a horse?

<p>Increased blood viscosity due to dehydration. (B)</p> Signup and view all the answers

When describing a cardiac murmur, timing is a critical characteristic. A systolic murmur is heard during which phase of the cardiac cycle?

<p>Between the S1 and S2 heart sounds. (C)</p> Signup and view all the answers

A holosystolic murmur is characterized by its duration. Which statement BEST describes the temporal extent of a holosystolic murmur?

<p>Occupying the entire systolic phase, starting with S1 and extending to S2. (C)</p> Signup and view all the answers

You auscultate a cardiac murmur and grade its intensity as a Grade 4/6. According to the grading scale for cardiac murmurs, what is a defining characteristic of a Grade 4 murmur?

<p>Loud murmur, widespread radiation, but without a palpable thrill. (B)</p> Signup and view all the answers

Point of maximal intensity (PMI) is an important characteristic when describing a cardiac murmur. What does the PMI primarily indicate about the origin of a murmur?

<p>The valve or location where the murmur is loudest, suggesting its anatomical source. (B)</p> Signup and view all the answers

Functional or 'innocent' cardiac murmurs can occur in horses, particularly athletic ones. Which type of functional murmur is MOST commonly auscultated in horses, especially during periods of high cardiac output?

<p>Systolic ejection murmur over the aortic or pulmonic valve. (D)</p> Signup and view all the answers

Pathologic cardiac murmurs in horses are most commonly associated with which of the following underlying mechanisms?

<p>Incompetent or regurgitant heart valves. (D)</p> Signup and view all the answers

Second-degree AV block is considered a common and often physiological arrhythmia in horses. Which of the following statements accurately describes a key characteristic of second-degree AV block in horses?

<p>It typically results in a regularly irregular rhythm that becomes more regular with exercise. (A)</p> Signup and view all the answers

On an ECG of a horse with Mobitz Type I second-degree AV block (Wenckenbach phenomenon), what is the hallmark ECG finding?

<p>Progressive lengthening of the P-R interval until a QRS complex is dropped. (C)</p> Signup and view all the answers

Physiological second-degree AV block in horses is often attributed to high vagal tone. Which of the following clinical scenarios is MOST likely to abolish or diminish physiological second-degree AV block?

<p>Mild to moderate exercise. (B)</p> Signup and view all the answers

Is the following statement true or false? 'All cardiac murmurs in horses indicate abnormal blood flow and underlying cardiac pathology.'

<p>False (B)</p> Signup and view all the answers

Which of the following statements regarding second-degree AV block in horses is FALSE?

<p>It is always a pathologic arrhythmia requiring immediate treatment. (D)</p> Signup and view all the answers

Cardiac arrhythmias are broadly classified based on their origin. Supraventricular arrhythmias originate from which anatomical locations in the heart?

<p>Atria, AV node, or sinoatrial (SA) node. (B)</p> Signup and view all the answers

Which of the following is considered a COMMON cause of cardiac arrhythmias in horses, particularly both supraventricular and ventricular types?

<p>Electrolyte imbalances (e.g., hypokalemia, hypocalcemia). (D)</p> Signup and view all the answers

Atrial fibrillation (AF) is the most common pathologic arrhythmia in horses. Which of the following statements accurately describes a key etiological factor in equine atrial fibrillation?

<p>The majority of equine atrial fibrillation cases (&gt;70%) occur without identifiable underlying cardiac disease (lone AF). (B)</p> Signup and view all the answers

What is a HALLMARK clinical feature of 'lone' atrial fibrillation in horses at rest?

<p>Normal heart rate and absence of abnormal clinical signs at rest. (A)</p> Signup and view all the answers

On an electrocardiogram of a horse with atrial fibrillation, which of the following ECG findings is MOST characteristic?

<p>Irregular R-R intervals with absent P waves and presence of fibrillatory 'f' waves. (D)</p> Signup and view all the answers

Historically, which antiarrhythmic drug was commonly used for chemical conversion of atrial fibrillation to normal sinus rhythm in horses, though its use is now limited due to availability and toxicity concerns?

<p>Quinidine sulfate. (B)</p> Signup and view all the answers

Transvenous electrical cardioversion (TVE) is now a preferred method for treating atrial fibrillation in horses. What is a significant advantage of TVE over pharmacological conversion using quinidine?

<p>TVE has a lower risk of proarrhythmic side effects and systemic toxicity compared to quinidine. (A)</p> Signup and view all the answers

If a horse with atrial fibrillation is not converted to normal sinus rhythm, or owners decline conversion therapy, what is a CRITICAL consideration for the horse's future management, especially if ridden?

<p>Performance of an exercise stress test with ECG monitoring to assess for exercise-induced ventricular arrhythmias. (C)</p> Signup and view all the answers

In equine cardiology, the S4 heart sound is associated with atrial contraction and increased ventricular filling. Under which of the following clinical scenarios would the presence of an S4 heart sound be considered MOST indicative of underlying cardiac pathology, rather than a normal finding?

<p>A geriatric horse presenting with exercise intolerance and a history of aortic regurgitation. (C)</p> Signup and view all the answers

When performing equine auscultation to assess cardiac valve function, strategic stethoscope placement is crucial. To optimally evaluate the tricuspid valve, where should the stethoscope be positioned?

<p>Right side, at the level of the 4th intercostal space, just above the point of the shoulder. (B)</p> Signup and view all the answers

A horse presents with exercise intolerance and intermittent episodes of collapse. An ECG reveals a regularly irregular rhythm with a heart rate of 28 bpm. Auscultation identifies 'dropped beats' that disappear with exercise. While physiological 2nd degree AV block is considered, which additional clinical finding would MOST strongly suggest a PATHOLOGICAL, rather than physiological, 2nd degree AV block in this case?

<p>Jugular venous distention extending halfway up the neck at rest. (A)</p> Signup and view all the answers

Atrial fibrillation is a significant arrhythmia in horses, often impacting athletic performance. Which of the following statements BEST describes the underlying mechanism that distinguishes atrial fibrillation from other supraventricular tachyarrhythmias, such as atrial flutter?

<p>Atrial fibrillation is characterized by disorganized and chaotic atrial electrical activity, whereas atrial flutter typically involves a more organized, rapid re-entrant circuit in the atria. (C)</p> Signup and view all the answers

Differentiating ventricular tachycardia (VT) from supraventricular tachycardia (SVT) with aberrancy is critical for appropriate treatment and prognosis in equine cardiology. Which ECG characteristic is the MOST RELIABLE indicator for distinguishing VT from SVT with aberrant ventricular conduction?

<p>QRS complex duration and morphology. (D)</p> Signup and view all the answers

An older equine athlete is diagnosed with a grade 3/6 systolic murmur loudest over the left heart base. Considering the common cardiac conditions in older horses, which of the following is the MOST likely underlying cause of this murmur?

<p>Aortic valve regurgitation secondary to age-related valve degeneration. (A)</p> Signup and view all the answers

Thoracic radiography has limited direct application in assessing the equine heart itself. However, it remains a valuable diagnostic tool in equine cardiology. What is the PRIMARY clinical utility of thoracic radiographs in horses with suspected cardiac disease?

<p>To assess for pulmonary changes associated with cardiac disease, such as cardiogenic pulmonary edema or pleural effusion. (A)</p> Signup and view all the answers

Echocardiography is a cornerstone of equine cardiac diagnostics. Why is a lower frequency ultrasound probe (2-3 MHz) typically preferred over higher frequencies for equine echocardiography?

<p>Lower frequency probes offer better penetration depth necessary to image the large equine heart, albeit with a trade-off in resolution. (C)</p> Signup and view all the answers

M-mode echocardiography is a valuable technique in equine cardiology. What is the MOST specific and primary application of M-mode echocardiography in the equine cardiac evaluation?

<p>Quantitative assessment of cardiac chamber dimensions and systolic function over time. (D)</p> Signup and view all the answers

Pulsed wave Doppler echocardiography is essential for evaluating blood flow in equine cardiology. What is the fundamental limitation of pulsed wave Doppler compared to continuous wave Doppler when assessing high-velocity blood flow, such as in severe valvular stenosis or regurgitation?

<p>Pulsed wave Doppler has a Nyquist limit, which restricts its ability to accurately measure velocities above a certain threshold, leading to aliasing. (C)</p> Signup and view all the answers

In equine color flow Doppler echocardiography, the color 'yellow' is sometimes observed within blood flow maps. What physiological phenomenon or technical artifact does 'yellow' typically represent in this context?

<p>Aliasing, indicating that blood flow velocity exceeds the Nyquist limit of the color Doppler scale. (B)</p> Signup and view all the answers

Cardiac Troponin I (cTnI) is used in equine medicine as a biomarker for myocardial injury. In which of the following clinical scenarios would measuring cTnI levels provide the MOST diagnostically valuable information?

<p>Evaluating a horse with suspected ionophore toxicity or myocarditis. (A)</p> Signup and view all the answers

A horse owner reports that their horse is 'not performing as well' and 'tires easily' during exercise. To assess for potential cardiac involvement in this exercise intolerance, which historical detail would be MOST critical to elicit during your initial phone consultation?

<p>Any episodes of coughing, nasal discharge, or increased respiratory effort, especially after exercise. (D)</p> Signup and view all the answers

A horse presents with acute onset of weakness, ataxia, and collapsing episodes. While neurological and musculoskeletal issues are initially considered, which specific historical or clinical finding would MOST strongly suggest a primary cardiac etiology as the cause of these 'neurological-like' signs?

<p>Observation of pale or cyanotic mucous membranes during an episode. (A)</p> Signup and view all the answers

A horse is diagnosed with third-degree atrioventricular (AV) block. What is the IMMEDIATE clinical significance of this arrhythmia in terms of physical examination findings and patient management?

<p>It is associated with a consistently slow heart rate, often leading to reduced cardiac output and potential for syncope, necessitating urgent evaluation for pacemaker implantation. (D)</p> Signup and view all the answers

A horse presents with coughing and nasal discharge described as frothy and blood-tinged. In the context of equine cardiology, what is the MOST concerning interpretation of these respiratory signs?

<p>Pulmonary edema secondary to left-sided congestive heart failure. (D)</p> Signup and view all the answers

During a routine pre-purchase examination of a sport horse, you palpate the facial artery to assess the pulse. Which pulse characteristic is MOST important to evaluate in the context of a cardiovascular assessment?

<p>Pulse rhythm and regularity. (B)</p> Signup and view all the answers

During cardiac auscultation, which component is MOST crucial for a comprehensive assessment beyond simply determining the heart rate?

<p>Systematically evaluating heart sounds, rhythm, and presence of murmurs across all auscultation points. (B)</p> Signup and view all the answers

The S1 heart sound, often described as 'lub,' is primarily attributed to the closure of which cardiac valves in the equine heart?

<p>Mitral and tricuspid valves. (A)</p> Signup and view all the answers

To effectively auscultate the pulmonic valve area in a horse, where should the stethoscope be optimally placed in relation to anatomical landmarks?

<p>Left side, 2nd-3rd intercostal space, high near the level of the shoulder. (B)</p> Signup and view all the answers

Cardiac murmurs are generated by turbulent blood flow. Which factor is LEAST likely to directly contribute to the generation of a cardiac murmur in a horse?

<p>Increased blood viscosity due to severe dehydration. (A)</p> Signup and view all the answers

A holosystolic murmur is defined by its duration. Which statement BEST describes the temporal extent of a holosystolic murmur?

<p>Extends throughout the entire systolic phase, from S1 to S2. (B)</p> Signup and view all the answers

Second-degree AV block is considered a common and often physiological arrhythmia in horses. Which statement accurately describes a key characteristic of physiological second-degree AV block in horses?

<p>It is characterized by a regularly irregular rhythm with intermittent dropped QRS complexes, and typically abolishes with exercise. (D)</p> Signup and view all the answers

Physiological second-degree AV block in horses is often attributed to high vagal tone. Which clinical scenario is MOST likely to abolish or diminish physiological second-degree AV block?

<p>Excitement or exercise, leading to increased sympathetic drive. (B)</p> Signup and view all the answers

Which statement regarding second-degree AV block in horses is FALSE?

<p>Pathological second-degree AV block always resolves with atropine administration. (D)</p> Signup and view all the answers

Which is considered a COMMON cause of cardiac arrhythmias in horses, particularly both supraventricular and ventricular types?

<p>Idiopathic causes and autonomic imbalances. (C)</p> Signup and view all the answers

Atrial fibrillation (AF) is the most common pathologic arrhythmia in horses. Which statement accurately describes a key etiological factor in equine atrial fibrillation?

<p>A significant proportion of equine atrial fibrillation cases are 'lone' or idiopathic, often associated with large atrial size and vagal tone, particularly in athletic horses. (A)</p> Signup and view all the answers

On an electrocardiogram of a horse with atrial fibrillation, which ECG finding is MOST characteristic?

<p>Irregular R-R intervals, absence of P waves, and presence of fibrillatory ('f') waves. (C)</p> Signup and view all the answers

In equine cardiology, how does the use of a continuous wave Doppler differ fundamentally from pulsed wave Doppler in echocardiography?

<p>Continuous wave Doppler can accurately measure high-velocity blood flow, while pulsed wave Doppler has limitations due to aliasing. (D)</p> Signup and view all the answers

A horse presents with a history of recent antibiotic treatment for a respiratory infection and now exhibits clinical signs of heart failure. Which underlying mechanism should be MOST suspected as a potential cause or contributing factor to the heart failure?

<p>Myocardial damage due to bacterial endocarditis and subsequent valvular insufficiency. (B)</p> Signup and view all the answers

An ECG reveals a supraventricular arrhythmia in a horse with normal QRS complexes. Given the context of the arrhythmia's origin, which of the following best describes the pathway of electrical conduction in comparison to ventricular arrhythmias?

<p>Supraventricular arrhythmias originate above the ventricles with normal conducting pathways resulting in normal QRS complexes. (A)</p> Signup and view all the answers

In a horse diagnosed with atrial fibrillation, why is an exercise stress test particularly important if the owner is considering riding the horse without attempting cardioversion?

<p>To evaluate the potential for life-threatening ventricular arrhythmias or sudden death during exertion. (D)</p> Signup and view all the answers

A horse presents with clinical signs of tachydysrhythmia and elevated cardiac troponin I levels following a recent history of anorexia and diarrhea. Which of the following differentials is MOST likely, considering the horse's history and lab results?

<p>Ventricular and supraventricular arrhythmias secondary to severe GI disease and endotoxemia. (D)</p> Signup and view all the answers

What is the MOST critical therapeutic consideration when treating a horse with ionophore toxicity affecting the myocardium, given the potential complications and contraindications?

<p>Careful management of electrolyte abnormalities while avoiding calcium administration. (C)</p> Signup and view all the answers

A horse presents with acute onset of severe colic, muscle fasciculations, and progresses into cardiovascular collapse. Given the clinical presentation, which of the following toxicities should be HIGHLY suspected?

<p>Cantharidin toxicity from blister beetles. (A)</p> Signup and view all the answers

When evaluating a 3-year-old Thoroughbred racehorse with a Grade 3/6 holosystolic murmur auscultated over the right cardiac window, what is the MOST likely differential diagnosis to consider?

<p>Tricuspid Regurgitation (C)</p> Signup and view all the answers

If a horse is exhibiting signs of heart failure, which of the following clinical presentation findings is MOST indicative of progressing RIGHT-sided heart failure?

<p>Jugular pulse (B)</p> Signup and view all the answers

If a horse presents with a known history of recent caterpillar exposure and now exhibits clinical signs indicative of Pericardial Disease, what is the most likely pathophysiology and what diagnostic test would best support this?

<p>Pericardial Effusion due to Eosinophilic inflammation, supported by cytology. (C)</p> Signup and view all the answers

In a horse with a history of cardiac disease, what is the MOST concerning implication of observing frothy, blood-tinged nasal discharge during a physical examination?

<p>Pulmonary edema secondary to left-sided heart failure. (A)</p> Signup and view all the answers

What is the MOST appropriate method for diagnosing a Uterine Artery Rupture post-foaling?

<p>Clinical Signs of Colic in an older mare, supported by abdominocentesis. (D)</p> Signup and view all the answers

In a horse with diagnosed aortic regurgitation that is considered clinically significant, what would be the MOST prudent long-term management recommendation for its athletic use?

<p>Avoiding exercise to limit increases in cardiac output and potential strain on the affected valve. (D)</p> Signup and view all the answers

In cases of equine sudden death during exercise with no gross lesions, what is the pathophysiologic reasoning that makes fatal arrhythmia considered the most probable cause?

<p>Arrhythmias disrupt electrical function, leading to hemodynamic collapse without structural changes. (D)</p> Signup and view all the answers

Why may diagnostic blockage when evaluating a lameness complaint lead to additional cardiac work-up?

<p>If the mare stumbles trotting following a diagnostic blockage, neurological components can be ruled out opening the door to cardiac causes. (A)</p> Signup and view all the answers

In the context of equine cardiology, what is the MOST relevant clinical implication of the relatively short half-life of cardiac troponin I (cTnI)?

<p>Serial measurements of cTnI are essential to assess ongoing myocardial injury. (C)</p> Signup and view all the answers

What mechanism causes second degree AV block to be generally abolished by exercise?

<p>Decreased Vagal Tone. (A)</p> Signup and view all the answers

What is now considered to be the common cause of Atrial Fibrillation?

<p>Idiopathic/ Lone cause, often attributed to athletic horses. (C)</p> Signup and view all the answers

What is the hallmark ECG finding for Atrial Fibrillation?

<p>Irregular R-R interval in the absence of a P wave. (B)</p> Signup and view all the answers

What specific characteristic is NOT an intended target of treatment when using antiarrhythmic therapy to handle life-threatening ventricular tachycardia?

<p>Frequency, monophasic, multifocal. (A)</p> Signup and view all the answers

Flashcards

Heart Sounds Order

The normal order of heart valve sounds: S1, S2, S3, S4

Auscultation

Using a stethoscope to listen to internal body sounds.

ECG (Electrocardiogram)

A graphic record of the heart's electrical activity.

Echocardiography

A noninvasive test using sound waves to create images of the heart.

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Cardiac Troponin I

A cardiac biomarker indicating myocardial injury.

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Exercise Intolerance in Horses

A horse showing reduced ability to perform exercise

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Normal Jugular Pulse

A normal jugular pulse should be visible at the most distal third. Pulses further up neck are not normal.

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Cardiac Auscultation

Listen for rate, rhythm, heart sounds and murmurs

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S1 Heart Sound

Closing of the AV valves like the Tricuspid and Mitral.

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S2 Heart Sound

Closing of the semilunar valves: aortic and pulmonic.

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S3 Heart Sound

Rapid ventricular filling.

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S4 Heart Sound

Atrial kick during late diastole.

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Cardiac Murmurs

Disruption of smooth blood flow often due to defects.

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Holosystolic Murmur

Murmur is heard throughout the entire systolic phase.

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Second Degree AV Block

2nd degree AV block that is normal in horses

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ECG Electrode Placement

The positive electrode is placed on the left cardiac window and the negative on the jugular furrow.

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Irregular R-R Interval

Atrial fibrillation identified on an ECG.

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Atrial Fibrillation

The most common pathologic arrhythmia, usually in athletic horses.

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Supraventricular Tachycardia

A main difference is the QRS complex - which looks normal in SVT.

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Ventricular Arrhythmia

The QRS complexes are bizarre, often very broad and unusual looking.

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Congenital Heart Disease

Most common defect is a ventricular septal defect, there is usually a genetic basis and can occur with other abnormalities

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Acquired Valvular Heart Disease

Most common cause is degenerative changes, mitral and tricuspid valves are often involved

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Cardiotoxin

An agent or substance that is specifically toxic to the heart.

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Clinical Signs of Heart Failure

Exercise intolerance, tachycardia, arrhythmia, murmur, right or left sided heart failure.

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Right Heart Failure Signs

The key clinical signs are Jugular Pulse, Ventral Edema, and Ascites.

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Left Heart Failure Signs

Pulmonary edema and coughing are key signs of Left Heart Failure.

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Myocardial Diseases

Infectious agents, toxins, drugs, and ischemia or hypoxia are causes.

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Azotemia

Abnormally high concentration of nitrogenous waste products in the blood.

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Ionophore Toxicity

Caused by feed contamination. Ionophores react with polar cations.

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Echocardiography

A diagnosis of a heart problem caused by ionophore toxicity.

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Study Notes

  • Laurie Beard is a DVM, MS, Diplomate ACVIM
  • Laurie Beard is a Clinical Professor

Cardiac Objectives

  • Normal physiology and anatomy should be understood
  • The order of heart sounds is S1, S2, S3, S4
  • Cardiac valve locations should be known
  • Normal heart rate is important
  • Second degree AV block needs to be recognized
  • Auscultation can aid the process
  • Differentiation must be made from pathogenic arrhythmias
  • ECGs are helpful for differentiation
  • Atrial Fibrillation is an important pathogenic arrhythmia
  • Auscultation is important
  • ECG is important for Atrial Fibrillation
  • The main causes of Atrial Fibrillation should be known
  • Rx is important for Atrial Fibrillation
  • The main difference between ventricular tachycardia and supraventricular tachycardia should be known
  • How to treat life-threatening Ventricular Tachycardia is important
  • The most common cardiac murmur of older and athletic horses should be known
  • DDX- myocardial injury/disease
  • Clinical signs and Rx for Heart Failure should be known

Diagnostic Tools for Cardiology

  • Important tools include thinking, using a stethoscope and ECG

ECG

  • The placement for base apex ECG includes:
  • Positive electrode on the left cardiac window
  • Negative electrode on the jugular furrow
  • ECG is useful for heart rhythm, but not for heart size in horses
  • ECG use includes continuous (Holter) monitoring, and during exercise

Thoracic Radiographs

  • Radiographs are limited to assess heart
  • Radiographs can provide information on the lungs
  • Information can be related to cardiac disease

Echocardiography

  • A low frequency probe (2 to 3 mHz) is used
  • Useful for anatomy of heart
  • Useful to assess chamber size, valves, contractility, and blood flow patterns
  • Echocardiography is expensive but getting cheaper

M-Mode & Doppler

  • M-Mode measures movement of cardiac structures over time
  • Pulsed Wave Doppler uses 1 crystal with short bursts of US
  • Pulsed Wave Doppler is specific to "Sample Area"
  • Pulsed Wave Doppler assesses the velocity and direction
  • Pulsed Wave Doppler provides spectral Characteristics
  • Pulsed Wave Doppler downside: Maximum velocity – can't measure beyond
  • Color Flow Doppler provides pulse wave over a 2-D or M-Mode
  • Red signifies blood toward
  • Blue signifies blood away
  • Yellow signifies aliasing velocity

Other Tools

  • Cardiac Troponin I is a biomarker of myocardial injury
  • Cardiac Troponin I has a short half life
  • Continued elevation of Cardiac Troponin I is important
  • Cardiac Troponin I is useful for Myocarditis diagnosis
  • Cardiac Troponin I is useful with monensin exposure
  • Cardiac Troponin I is useful for recent publication – endotoxic colics

General Approach

  • A history is important
  • Clients will not directly say the horse has a heart problem
  • Most cases present for other problems

Clinical Signs

  • Exercise intolerance can be a common complaint
  • Exercise intolerance may not be reported
  • Neurological signs, Colic, Falling, Fainting may be indicators
  • Respiratory signs such as Coughing, Nasal discharge and EIPH may be indicators
  • Sudden death during exercise or with no gross lesions might indicate fatal arrhythmia
  • Incidental findings may occur during routine or prepurchase examinations

Lucy’s case study

  • Lucy is a 10 year old QH mare
  • Lucy presented with a complaint of lameness
  • Work-up included assessing for lameness and neurological disease (EPM?)
  • Lucy had a heart rate of 20 bpm & irregular
  • Third degree AV block requires a physical exam

General Examination

  • Includes palpating the pulse
  • At the facial artery
  • Assessing the Rhythm, Rate and Strength
  • Other arteries can also be assessed
  • Assess for venous distention in the jugular vein and lateral thoracic
  • Normal jugular pulse is seen in the distal 1/3 only when the head is up
  • Abnormal jugular pulse extends up the neck further indicating TV diseases, right ventricle failure or arrhythmias
  • Palpate the chest
  • For the left apical beat and to determine if a thrill is present

Mucous Membranes

  • Normal mucous membranes are pink with CRT < 3 seconds
  • Cyanotic Membrane contain > 5 gms of Deoxygenated hemoglobin
  • Cyanosis is affected by % Oxygen saturation and Amount of Hemoglobin
  • Amount of Hemoglobin is affected by RBC #/PCV and Anemia
  • White Membranes indicate Blood Loss
  • Edema indicates volume overload
  • Edema indicates increased hydrostatic pressure
  • Ventral Edema is an example

Auscultation

  • Auscultation includes assessing the Rate, Heart sounds, Rhythm, and Murmur
  • Heart sounds are:
    • S1 = AV closes (TV & MV) “lub”
    • S2 = Semilunar (Aortic & Pulmonic) "dup”
    • S3 = Rapid ventricular filling ("uh")
    • S4 = atrial kick (“ba”) -S4, S1, S2, S3 (ba, lub,dup, uh)
  • It is normal to hear all 4 heart sounds
  • Check the valve regions

Cardiac Murmurs

  • They may be due to Turbulent Blood Flow which is a resonance in adjacent structures
  • Some are due to pathology
  • Some can also be normal (functional)
  • They are also due to Turbulent Blood Flow
  • They relate to Blood Velocity and Blood Viscosity
  • Blood Viscosity can be affected by Anemia, and Dehydration
  • Assess the timing of the murmurs: Systolic, Diastolic or Continuous
  • Measure the duration
  • Holosystolic, holodiastolic murmurs are very common
  • Measure the Intensity of the murmurs using a Grade 1-6 system
  • Grade 1- very soft, local area (inconsistent)
  • Grade 2 soft, heard immediately
  • Grade 3- moderate intensity
  • Grade 4- loud, widespread & no palpable thrill
  • Grade 5, louder & thrill
  • Grade 6- heard w stethoscope off chest
  • Assess the Quality or Pitch
  • Check the point of Maximal Intensity over a valve plus the direction the sound radiates

Functional Cardiac Murmurs

  • Flow murmurs are normal
  • Systolic murmurs involve ejection of blood through the Aortic or Pulmonic Valve (common)
  • Diastolic murmurs involves rapid ventricular filling

Pathologic Cardiac Murmurs

  • Incompetent or Regurgitatant Valves
  • VSD
  • Stenotic valves are very uncommon

Heart Rhythm

  • Second Degree AV block is a heart rhythm
  • Its not really an arrhythmia
  • Its normal in horses
  • It is Regularly- irregular
  • Can be described as “Tap through It”

Normal ECG

  • 2nd Degree AV block are normal
  • Mobitz Type I is normal
  • Wenckenbach phenomenon is normal
  • Progressive lengthening P-R interval is normal
  • Second Degree AV Block has associated findings
  • High Vagal Tone
  • Low Heart Rate
  • S4 heard
  • Second Degree AV Block are Abolished by exercise

Review

  • The order of heart sounds is S4, S1, S2, S3
  • Must know location of valves on left and right cardiac window
  • Cardiac heart murmurs indicate abnormal blood flow
  • Second degree AV block is common in fit athletic horses and results in an irregularly, irregular heart rhythm

Cardiac Arrhythmias

  • Arrhythmias can be Supraventricular (Atrial or AV node) or Ventricular
  • Arrhythmia causes:
  • Idiopathic
  • Autonomic Imbalances
  • Electrolyte Abn
  • Myocardial Inflammation
  • Toxins

Atrial Fibrillation

  • A common pathologic arrhythmia
  • 2 main causes
  • Usually (70%) no underlying heart disease -idiopathic or Lone AF with High Vagal Tone, Large Hearts, Athletic Horses
  • Can also be due to underlying cardiac disease
  • Lone Atrial Fibrillation
  • No abnormal signs at rest
  • normal HR
  • Exercise intolerance in athletic horses
  • Irregular irregular rhythm
  • Electrocardiogram characteristics:
  • Irregular R-R interval
  • Absent p waves
  • Little f waves
  • Treatment options:
  • Treat underlying Cardiac disease
  • Idiopathic or Lone cases can convert to normal sinus rhythm
  • Quinidine sulfate human drug was previously used but has been removed due to toxicity
  • Transvenous electrical cardioconversion (TVE) has replaced Quinidine
  • Successful in large number of cases and fewer side effects than Quinidine
  • Transvenous electrical cardioconversion (TVE) requires special equipment & trained people
  • Transvenous electrical cardioconversion (TVE) uses Jugular Catheter, that's positioned into RA
  • Horse requires to be anesthetized
  • Many horses relapse
  • If unable to convert to normal sinus rhythm or owners don't want to convert, assess whether (should they be ridden)?
  • An exercise stress test is needed in order to assess Concerns of Ventricular tachycardia or even V. fib and Falling/sudden death

Ventricular Arrhythmia vs Supraventricular Arrhythmias

  • Exercise Stress Test: R on T indicates a ventricular event
  • Ventricular Arrhythmia has Bizarre QRS complexes
  • Supraventricular Arrhythmias
  • Originate with normal conducting pathways, with normal QRS Complexes
  • Includes sinus tachycadria (SA node), Atrial tachycardia (atria), Atrial fibrillation (atria), Re-entry (accessory pathways), and At AV node
  • Atrial Tachycardia is a type of SVT
  • Diagnosing cause can be hard

Baron's Case Study

  • The cardiologists had no idea of the original diagnosis
  • We thought atrial tachycardia
  • The case was sent to Cornell
  • Diagnosis of re-entry (accessory pathway) from ventricles back to atria

Ventricular and Supraventricular arrhythmias

  • They are often due to Myocarditis (infectious, toxins)
  • Elevated Troponin I concentrations
  • Severe GI disease
  • Endotoxemia
  • Persistent tachycardia
  • Electrolyte imbalance
  • Hypovolemia
  • There are also Idiopathic cases
  • Treatment includes:
  • Stall rest
  • Treat underlying disease with Electrolyte abnormalities and Steroids for Myocarditis

Antiarrhythmic Therapy

  • For Ventricular cases use an Antiarrhythmic Therapy
  • When HR > 80 with R on T events
  • Lidocaine and MgSO4 are options
  • Watch for
  • an increase the Frequency, that's monophasic, and multifocal
  • Syncope, depression, and reduced CO

Ventricular & Supraventricular causes

  • Depending on the cause, for Atrial fibrillation use TVE, or Recent report – Europe – use ablation (via catheter) to treat sustained atrial tachycardia

Congenital Heart Disease

  • VSD is the MOST Common Defect
  • Genetic Basis in Arabians, Welsh Mt. Ponies, STB, and Warmbloods
  • May occur with other cardiac abnormalities, and also causes congenital defect in humans
  • VSD is Not always associated with poor performance
  • VSD Can be an incidental finding
  • VSD Clinical signs vary:
  • None signs
  • Exercise Intolerance, and signs of CHF
  • Holosystolic Murmurs over TV
  • Small defects have loudest murmurs
  • Other Defects exist such as:
  • PDA- which should close at 72 hours
  • Tetralogy of Fallot
  • plus others

Acquired Valvular Heart Disease

  • Stenotic Valvular Lesions- RARE in Horses
  • Regurgitation- COMMON!
  • Lesions of Mitral & Tricuspid which have Systolic origins
  • Lesions of Aortic and Pulmonic which have Diastolic origins
  • Valvular Lesions can be cause due to:
  • Degenerative changes (common)
  • Bacterial endocarditis
  • Ruptured Chordae Tendinae
  • Inflammatory Valvulitis

Mitral & Tricuspid Regurgitation

  • It is Very common, with TV>MV with athletic horses, and geriatric horses
  • The causes are Degenerative changes of valve, and will have Holosystolic Murmurs
  • These sounds will be Loudest over valve in question
  • Echocardiography-dx
  • Prognosis, Many times NOT clinically significant in Tricuspid cases
  • Echocardiography should assess Chamber Size, Contractility and Estimation of amount of regurgitation
  • High prevalence has been noted in race horses in training

Aortic Regurgitation (AR)

  • AR is common in Older horses
  • The cause is Degenerative Changes of Valve
  • AR causes Holodiastolic Murmur with Decrescendo pitch
  • AR is likely not clinically significant in OLDER Horses
  • AR is Usually detected – incidentally
  • AR will cause "Bounding Pulse" with Diastolic run off
  • An Echo can confirm AR to measure chamber size
  • Use of ECG and Exercise test

Case Study Of TB racehorse

  • The case includes a Grade 3/6 holosystolic murmur over right cardiac window
  • In these cases, the most likely cause related to Tricuspid Regurgitation

Valvular Stenosis and Regurgitation

  • AR or Aortic Regurgitation
  • MR or Mitral Regurgitation
  • TS or Tricuspid Stenosis
  • TR Tricuspid Regurgitation
  • Right sided holosystolic is common for cardiac murmur specific in geriatric horses

Myocardial Diseases

  • Common causes include:
  • Infectious agents
  • Toxins: (ionophores, plants)
  • Drugs
  • Ischemia/hypoxia
  • Metabolic/nutritional
  • Damage may or may not result in Heart Failure
  • Clinical signs consistent with heart failure
  • Myocarditis
  • Is often after Prior infections such as Influenza and Strep
  • Has Immune Mediated (purpura?) origins, but Difficult to prove
  • Requires Troponin I to be increased
  • Monensin is the most common cause of Ionophore Toxicity
  • A toxic dose is 2-3 mg/kg
  • Salinomycin and Lasalocid are other cases
  • Often due to contaminated Feedmill accident, especially seen this spring
  • Causes Horses to get into cattle feed
  • Clinical Signs-Ionophore:
  • None- to multiple body systems from Weakness, Colic, and Ataxia
  • Acute Death in 12-36 hours
  • Chronically leads to Congestive Heart Failure
  • Blood work-Ionophore will show:
  • Decreases in electrolytes
  • Increases in muscle enzymes and Troponin I
  • Azotemia
  • Dx-Ionophore depends on
  • Echocardiography-myocardial disease
  • Checking for ionophores in the Feed or Stomach
  • Tx-Ionophores will show:
  • Mineral Oil- as an early step
  • Supportive (fluids)
  • Electrolyte abnormalities must be managed
  • Be careful with calcium
    • Hypocalcemia can is transient, while Calcium can irritating to injured myocardium
  • Digoxin & Calcium channel blockers are CONTRAINDICATED
  • Plants-Glycoside are often the cause
  • Including Taxus (Japanese Yew), Foxglove, and Bella donna
  • Cardiotoxins such as Canthardin (Direct Cardiotoxic Effects) and Snake Venom

Heart Failure

  • Clinical signs:
  • Exercise intolerance
  • Cachexia
  • Tachycardia
  • Murmur or Thrill
  • Arrhythmia
  • Right sided indicates -Jugular pulse
  • Ventral edema
  • Ascites
  • Left sided will cause -Pulmonary edema -Cough
  • If suspecting Heart Failure
  • Run Clinical Signs
  • Echocardiography
  • Try to determine cause
  • Treatment-Heart Failure
  • Treat Underlying Disease…
  • If Heart Failure use:
  • Furosemide
  • Digoxin not with acute monensin
  • ACE-inhibitors
  • Vasodilators
  • These cases should be Pasture Pet/Breeding only
  • Owners- should NOT ride to avoid Danger of falling/sudden death

Other Disease

  • Pericardial Disease includes:
  • Pericardial Effusion
  • Fibrinous Pericarditis
  • An increased rate of Pericarditis in Kentucky associated with caterpillars
  • Eosinophilic inflammation
  • Pericarditis causes:
  • Idiopathic (sterile- unknown reasons)
  • Infection (viral, bacterial)
  • Often associated with pneumonia
  • Traumatic
  • Neoplasia
  • Vascular Diseases:
  • Thrombophlebitis
  • Jugular Vein
  • Caused by Injections or Catheters
  • Primary Disease related to Hypercoagulability
  • Predisposes to thrombosis, that May or May Not be Septic
  • Arterial Rupture:
  • In Older Stallions causes Root of aorta
  • In Brood mares causes Middle uterine artery rupture
  • Uterine Artery Rupture occurs:
  • In Older Multiparous Mares that have Hemorrhage following foaling in the Broad Ligament or Into Abdomen
  • Colics may arise from a hematoma in broad ligament
  • Hemorrhage- RX
  • Keep patients quiet
  • Use IV Fluids with blood transfusion
  • Remove acepromazine
  • Also use Anti-fibrinolytic drugs such as aminocaproic acid and/or Chinese Herb- Yunnan baiyo

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