Epoetin alfa Flashcards

Study Notes

Classification of Epoetin alfa

Epoetin alfa, marketed as Epogen and Procrit, is classified as a hematopoietic drug.

Uses of Epoetin alfa

Primarily used to elevate hematocrit levels in patients with anemia.
Effective for individuals with chronic kidney failure.
Beneficial for anemias associated with malignancies and AIDS.

Usual Dosage and Administration

Administered subcutaneously (SQ) at a dosage of 3-500 units/kg per dose.
Given three times a week until the target hematocrit (Hct) range of 30-33% is achieved.

Desired Effects

Epoetin alfa is a glycoprotein that stimulates the production of red blood cells (RBCs).
It is produced in the kidneys and promotes erythropoiesis by stimulating the bone marrow.

Side Effects

Potential side effects include seizures, headaches, and hypertension.
May cause iron deficiency and clotting issues, especially in arteriovenous (AV) fistula.
Other reported effects include excessive sweating, bone pain, and arthralgias.

Nursing Implications

Avoid shaking the solution as it can denature the glycoprotein, making it biologically inactive.
Inspect the solution for particulate matter before use; do not administer if discolored or contains particles.

Client Teaching

Increasing hematocrit levels can enhance the sense of well-being and overall quality of life.
Important for patients to adhere to dietary and dialysis prescriptions.
Compliance with antihypertensive medications and dietary restrictions is crucial.
Advise against driving or engaging in hazardous activities during the first 90 days of treatment due to the risk of seizure activity.

Description

Test your knowledge on Epoetin alfa (Epogen, Procrit) with these flashcards. Each card covers key aspects such as classification, uses, and usual dosage for treatment. Perfect for students and healthcare professionals wanting to reinforce their understanding of this important hematopoietic drug.