Questions and Answers
What is the generic name of the drug?
What is the trade name of Epinephrine?
Adrenalin
What class does Epinephrine belong to?
Sympathomimetic
What is the action of Epinephrine?
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Epinephrine is indicated for ________ arrest.
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Which route(s) can Epinephrine be administered?
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There are contraindications for the use of Epinephrine in emergencies.
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What are some adverse effects of Epinephrine?
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What special consideration should be taken when administering Epinephrine to asthmatic children?
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What is the typical dose of Epinephrine for cardiac use?
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What is the dose of Epinephrine for anaphylaxis?
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Study Notes
Epinephrine Overview
- Generic name: Epinephrine
- Trade name: Adrenalin
Drug Class
- Classified as a sympathomimetic agent
- Mimics the effects of the sympathetic nervous system, triggering a "fight or flight" response
Mechanism of Action
- Activates Alpha and Beta adrenergic receptors
- Alpha receptors: Induces vasoconstriction
- Beta-1 receptors: Increases heart contractility, heart rate, and cardiac conduction velocity
- Beta-2 receptors: Relaxes bronchial smooth muscle and dilates skeletal vasculature
- Blocks histamine receptors to counteract allergic reactions
Clinical Indications
- Used during cardiac arrest situations such as:
- Asystole
- Pulseless Electrical Activity (PEA)
- Ventricular Fibrillation (VFib)
- Ventricular Tachycardia (VTach)
- Alternative treatment for symptomatic bradycardia and hypotension due to shock (not hypovolemic)
- Effective for allergic reactions, anaphylaxis, and asthma management
Administration Routes
- Administered via IV (intravenous), IO (intraosseous), IM (intramuscular), or ET (endotracheal) routes
Contraindications
- No contraindications in emergency situations
Adverse Effects
- Common side effects include:
- Nervousness and restlessness
- Headaches and tremors
- Pulmonary edema
- Dysrhythmias and chest discomfort
- Hypertension and tachycardia
- Nausea and vomiting
Special Considerations
- May cause syncope (fainting) in asthmatic children
- Can increase myocardial oxygen demand
- Important to double-check the dose and route before administration
Dosage Information
- Cardiac arrest: 1 mg of 1:10,000 concentration given IV/IO
- Anaphylaxis: 0.3-0.5 mg of 1:1,000 concentration administered via OM (oral mucosa)
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Description
Test your knowledge on epinephrine, its drug classification, mechanism of action, clinical indications, and administration routes. This quiz will cover essential information necessary for understanding how epinephrine works in emergency situations, including its role in cardiac arrest and allergic reactions.
