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Lecture 20

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Questions and Answers

Which molecular epigenetic mechanism involves specific posttranslational modifications combinations in different chromatin regions?

Chromatin condensation

microRNAs

DNA methylation

Histone modifications (correct)

What is the role of erasers in the histone code?

Introduce modifications on DNA and histone tails

Facilitate gene transcription

Remove the modifications introduced by writers (correct)

Bind to modifications using specialized domains

Which protein contributes to heterochromatin condensation by binding to histone H3 N-terminal tails trimethylated at lysine 9?

Chromatin remodeling enzyme

Heterochromatin protein 1 (HP1) (correct)

Histone methyltransferase

Histone acetylase

What is the proposed mechanism of histone deacetylation and hyperacetylation in yeast transcriptional control?

Ume6 repressor directed deacetylation of histone N-terminal tails Signup and view all the answers

What is the role of Gcn5 in yeast transcriptional control?

Hyperacetylates histone N-terminal tails Signup and view all the answers

What is the mechanism for maintaining histone H3 lysine 9 methylation during chromosome replication?

Random association of parent histones with daughter chromosomes Signup and view all the answers

What is the main role of pioneer transcription factors?

Facilitate chromatin decondensation Signup and view all the answers

What is the function of histone code writers?

Introduce modifications on DNA and histone tails Signup and view all the answers

Which protein removes the modifications introduced by histone code writers?

Erasers Signup and view all the answers

What is the role of Gcn4 in yeast transcriptional control?

Directs hyperacetylation of histone N-terminal tails Signup and view all the answers

What is the effect of chromatin condensation on gene transcription?

Blocks RNA pol and general TFs from interacting with gene promoters Signup and view all the answers

Which molecular mechanism involves modification of histone N-terminal tails in heterochromatin and euchromatin?

Histone acetylation Signup and view all the answers

Lecture 20

Choose a study mode

Podcast

Questions and Answers

Which molecular epigenetic mechanism involves specific posttranslational modifications combinations in different chromatin regions?

What is the role of erasers in the histone code?

Which protein contributes to heterochromatin condensation by binding to histone H3 N-terminal tails trimethylated at lysine 9?

What is the proposed mechanism of histone deacetylation and hyperacetylation in yeast transcriptional control?

What is the role of Gcn5 in yeast transcriptional control?

What is the mechanism for maintaining histone H3 lysine 9 methylation during chromosome replication?

What is the main role of pioneer transcription factors?

What is the function of histone code writers?

Which protein removes the modifications introduced by histone code writers?

What is the role of Gcn4 in yeast transcriptional control?

What is the effect of chromatin condensation on gene transcription?

Which molecular mechanism involves modification of histone N-terminal tails in heterochromatin and euchromatin?

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