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Questions and Answers
What is the primary composition of the tunica media in arteries?
What is the primary composition of the tunica media in arteries?
- Smooth muscle cells arranged circumferentially (correct)
- Collagenous tissue with subendothelial layers
- Elastic fibers in a longitudinally arrangement
- Endothelium layer with a thin external elastic lamina
Which blood vessels have a thicker media and a relatively narrow lumen?
Which blood vessels have a thicker media and a relatively narrow lumen?
- Venules
- Veins
- Arteries (correct)
- Capillaries
Which tunic separates the tunica media from the outermost tunic in arteries?
Which tunic separates the tunica media from the outermost tunic in arteries?
- External elastic lamina (correct)
- Endothelium layer
- Subendothelial layer
- Collagenous tissue
What is the main composition of the tunica adventitia in blood vessels?
What is the main composition of the tunica adventitia in blood vessels?
What is the main function of the numerous elastic laminae in elastic arteries?
What is the main function of the numerous elastic laminae in elastic arteries?
Why do veins have a larger lumen compared to arteries?
Why do veins have a larger lumen compared to arteries?
What is the function of the Spongiosa layer in heart valves?
What is the function of the Spongiosa layer in heart valves?
Which type of muscle is found in the walls of vessels larger than capillaries?
Which type of muscle is found in the walls of vessels larger than capillaries?
What is the main function of the endothelium in vascular walls?
What is the main function of the endothelium in vascular walls?
Where are Purkinje fibers located in the heart?
Where are Purkinje fibers located in the heart?
Which layer of the heart valves is covered with endothelium and adjacent to the ventricular or atrial surface of each valve?
Which layer of the heart valves is covered with endothelium and adjacent to the ventricular or atrial surface of each valve?
What is the role of fibrous extensions from the dense irregular connective tissue of the skeletal rings of the heart in heart valves?
What is the role of fibrous extensions from the dense irregular connective tissue of the skeletal rings of the heart in heart valves?
What is the function of the epicardium in the heart?
What is the function of the epicardium in the heart?
Which layer of the heart consists mainly of cardiac muscle fibers arranged spirally around each heart chamber?
Which layer of the heart consists mainly of cardiac muscle fibers arranged spirally around each heart chamber?
What type of tissue forms part of the cardiac skeleton in the heart?
What type of tissue forms part of the cardiac skeleton in the heart?
What is the main function of the endocardium in the heart?
What is the main function of the endocardium in the heart?
What is the role of the pericardial fluid in the heart?
What is the role of the pericardial fluid in the heart?
Which layer of the pericardium corresponds to the visceral layer and is supported by a layer of loose connective tissue?
Which layer of the pericardium corresponds to the visceral layer and is supported by a layer of loose connective tissue?
What is the role of endothelial cells in inflammation and local immune responses?
What is the role of endothelial cells in inflammation and local immune responses?
Which factor is rapidly expressed on the luminal surface of endothelial cells in response to injury or infection?
Which factor is rapidly expressed on the luminal surface of endothelial cells in response to injury or infection?
What is the function of Vascular Endothelial Growth Factor (VEGF)?
What is the function of Vascular Endothelial Growth Factor (VEGF)?
What is the composition of the subendothelial layer beneath the endothelium?
What is the composition of the subendothelial layer beneath the endothelium?
Which layer allows expansion, especially during high blood pressure?
Which layer allows expansion, especially during high blood pressure?
What is the function of Weibel–Palade bodies in endothelial cells?
What is the function of Weibel–Palade bodies in endothelial cells?
What is the main function of elastic arteries?
What is the main function of elastic arteries?
What is a distinguishing feature of conducting arteries?
What is a distinguishing feature of conducting arteries?
Which part of the artery helps in regulating blood pressure?
Which part of the artery helps in regulating blood pressure?
What is the main function of distributing arteries?
What is the main function of distributing arteries?
Which structural feature is unique to larger muscular arteries?
Which structural feature is unique to larger muscular arteries?
What allows metabolic exchange between blood and surrounding tissues in capillaries?
What allows metabolic exchange between blood and surrounding tissues in capillaries?
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Study Notes
Vascular Wall Structure
- Consists of three tunics: tunica intima, tunica media, and tunica adventitia
- Tunica intima: innermost layer, composed of endothelium and subendothelial layer
- Tunica media: middle layer, composed of smooth muscle cells and elastic fibers
- Tunica adventitia: outermost layer, composed of longitudinally arranged collagenous tissue and few elastic fibers
Arteries
- Elastic arteries: thick tunica media with elastic lamellae, found in aorta and pulmonary artery
- Muscular arteries: thicker media and narrower lumen, found in distributing arteries
- Arteries have a thicker media and relatively narrower lumen compared to veins
Veins
- Thicker adventitia and larger lumen compared to arteries
- Intima often folded to form valves
- Veins have a larger lumen and thicker adventitia compared to arteries
Capillaries
- Composed of a single layer of endothelial cells and their basal lamina
- Allow for metabolic exchange between blood and surrounding tissues
- Form blood vascular networks and function in groups called capillary beds
- Major structural variations occur in organs with different functions
Heart Valves
- Composed of connective tissue overlying endocardium
- Three layers: fibrosa, spongiosa, and ventricularis
- Acts as a shock absorber to dampen vibration associated with valve closing
Heart Tissues
- Endocardium: innermost layer of the heart, composed of endothelium and supporting connective tissue
- Myocardium: middle layer of the heart, composed of cardiac muscle fibers and connective tissue
- Epicardium: outermost layer of the heart, composed of a simple squamous mesothelium and loose connective tissue
Cardiac Skeleton
- Dense irregular fibrous connective tissue
- Forms part of the interventricular and interatrial septa
- Surrounds all valves of the heart and extends into the valve cusps and chordae tendineae
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