Enzymes and Their Functions in Medicine

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Questions and Answers

What is the primary function of streptokinase in clinical settings?

  • Depolymerizing DNA
  • Digesting fibrin clots (correct)
  • Killing leucocytes
  • Breaking down hyaluronic acid

Which enzyme assists in the spreading of microorganisms in infected tissues by breaking down hyaluronic acid?

  • Proteinase
  • Streptodornase
  • Streptokinase
  • Hyaluronidase (correct)

Which enzyme is responsible for the depolymerization of DNA?

  • Streptodornase (correct)
  • Amylase
  • Hyaluronidase
  • Streptokinase

Which of the following enzymes is related to the killing of leucocytes?

<p>Diphosphopyridine nucleotidases (B)</p> Signup and view all the answers

What is the primary role of proteolytic enzymes such as proteinase and amylase produced by certain strains?

<p>Digesting proteins and carbohydrates (C)</p> Signup and view all the answers

Flashcards

Streptokinase function

Converts plasminogen to plasmin, which breaks down fibrin clots.

Streptodornase function

Breaks down DNA.

Hyaluronidase function

Breaks down hyaluronic acid, a connective tissue component, helping microbes spread.

Diphosphopyridine nucleotidaes effect

Kills white blood cells (leukocytes).

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Proteinase & Amylase Role

Some bacteria produce these enzymes.

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Study Notes

Streptokinase (Fibrinolysin)

  • Converts plasminogen to plasmin, which breaks down fibrin clots.
  • Administered intravenously for coronary, pulmonary, or venous thrombosis.

Streptodornase (Streptococcal Deoxyribonuclease)

  • Breaks down DNA.

Hyaluronidase

  • Splits hyaluronic acid, a component of connective tissue.
  • Aids microorganisms in spreading through infected areas (spreading factor).

Diphosphopyridine Nucleotidaes

  • Associated with the killing of leukocytes (white blood cells).

Other Enzymes

  • Some strains produce proteinase and amylase.

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