Enzymes and Digestive System
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Questions and Answers

What is the lock and key theory of enzyme-substrate interaction?

Enzymes have a specific 3D structure that exactly matches the shape of a molecule of substrate, allowing the substrate to fit into the active site of the enzyme like a key in a lock.

What happens to an enzyme if the temperature and pH changes beyond its optimum?

If the temperature and pH changes beyond an enzyme's optimum, the shape of the enzyme irreversibly changes, affecting the shape of the active site and rendering the enzyme denatured, which means it will no longer work.

How do enzymes work in the digestive system, and what is the role of bile in the process?

Enzymes in the digestive system break down large indigestible molecules into smaller digestible molecules, acting like scissors. Bile, which is made in the liver and stored in the gall bladder, is alkaline to neutralize hydrochloric acid from the stomach and emulsifies fat to form small droplets, increasing the surface area and rate of fat breakdown by lipase.

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