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Enzymes and Biochemical Reactions: Alkaline Phosphatase

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Questions and Answers

What is the primary function of alkaline phosphatase enzymes?

To catalyze biochemical reactions without being consumed (correct)
To alter the equilibrium point of biochemical reactions
To synthesize new proteins in the body
To break down complex carbohydrates

What is the primary source of alkaline phosphatase in the sera of normal adults?

Liver and biliary tract (correct)
Intestines and spleen
Bones and osteoblasts
Kidney and placenta

What is the function of phosphatases in the body?

To regulate hormone production
To synthesize organic phosphates
To transport nutrients across cell membranes
To cleave the ester bond between the phosphate group and the organic residue (correct)

What is the optimum pH for alkaline phosphatase activity?

9.0 (D) Signup and view all the answers

What is one of the biological functions of alkaline phosphatase in the intestines?

To transport fatty acids and phosphates (B) Signup and view all the answers

What is the most useful technique for analyzing alkaline phosphatase isoenzymes?

Electrophoresis (A) Signup and view all the answers

What is the primary purpose of ordering an ALP test?

To diagnose and monitor liver or bone disorders (A) Signup and view all the answers

What is the normal range of ALP for an adult?

32 - 92 IU/L (D) Signup and view all the answers

Why do children and adolescents exhibit higher total alkaline phosphatase activity than adults?

Due to a higher production of the bone isoform of this enzyme (D) Signup and view all the answers

What is the characteristic of ALP elevation in extrahepatic obstruction?

Marked elevation, more than threefold (A) Signup and view all the answers

In which condition is the highest level of serum alkaline phosphatase activity encountered?

Paget's disease (A) Signup and view all the answers

What is the result of hypophosphatasia on ALP levels?

Significantly decreased (B) Signup and view all the answers

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