12 Questions
What is the primary function of alkaline phosphatase enzymes?
To catalyze biochemical reactions without being consumed
What is the primary source of alkaline phosphatase in the sera of normal adults?
Liver and biliary tract
What is the function of phosphatases in the body?
To cleave the ester bond between the phosphate group and the organic residue
What is the optimum pH for alkaline phosphatase activity?
9.0
What is one of the biological functions of alkaline phosphatase in the intestines?
To transport fatty acids and phosphates
What is the most useful technique for analyzing alkaline phosphatase isoenzymes?
Electrophoresis
What is the primary purpose of ordering an ALP test?
To diagnose and monitor liver or bone disorders
What is the normal range of ALP for an adult?
32 - 92 IU/L
Why do children and adolescents exhibit higher total alkaline phosphatase activity than adults?
Due to a higher production of the bone isoform of this enzyme
What is the characteristic of ALP elevation in extrahepatic obstruction?
Marked elevation, more than threefold
In which condition is the highest level of serum alkaline phosphatase activity encountered?
Paget's disease
What is the result of hypophosphatasia on ALP levels?
Significantly decreased
Test your knowledge of alkaline phosphatase enzymes, their role in biochemical reactions, and their production in various body tissues. Learn about the different forms of ALP and their high concentration in specific organs. Explore the concept of electrophoresis and its relation to enzyme identification.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
