Enzymes and Biochemical Reactions: Alkaline Phosphatase
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Questions and Answers

What is the primary function of alkaline phosphatase enzymes?

  • To catalyze biochemical reactions without being consumed (correct)
  • To alter the equilibrium point of biochemical reactions
  • To synthesize new proteins in the body
  • To break down complex carbohydrates

What is the primary source of alkaline phosphatase in the sera of normal adults?

  • Liver and biliary tract (correct)
  • Intestines and spleen
  • Bones and osteoblasts
  • Kidney and placenta

What is the function of phosphatases in the body?

  • To regulate hormone production
  • To synthesize organic phosphates
  • To transport nutrients across cell membranes
  • To cleave the ester bond between the phosphate group and the organic residue (correct)

What is the optimum pH for alkaline phosphatase activity?

<p>9.0 (D)</p> Signup and view all the answers

What is one of the biological functions of alkaline phosphatase in the intestines?

<p>To transport fatty acids and phosphates (B)</p> Signup and view all the answers

What is the most useful technique for analyzing alkaline phosphatase isoenzymes?

<p>Electrophoresis (A)</p> Signup and view all the answers

What is the primary purpose of ordering an ALP test?

<p>To diagnose and monitor liver or bone disorders (A)</p> Signup and view all the answers

What is the normal range of ALP for an adult?

<p>32 - 92 IU/L (D)</p> Signup and view all the answers

Why do children and adolescents exhibit higher total alkaline phosphatase activity than adults?

<p>Due to a higher production of the bone isoform of this enzyme (D)</p> Signup and view all the answers

What is the characteristic of ALP elevation in extrahepatic obstruction?

<p>Marked elevation, more than threefold (A)</p> Signup and view all the answers

In which condition is the highest level of serum alkaline phosphatase activity encountered?

<p>Paget's disease (A)</p> Signup and view all the answers

What is the result of hypophosphatasia on ALP levels?

<p>Significantly decreased (B)</p> Signup and view all the answers

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