Enzyme Markers in Clinical Significance

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CommodiousUnakite8363
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18 Questions

Which enzyme is commonly used as a marker for prostatic carcinoma?

Acid phosphatase (ACP)

What is the primary purpose of isoenzymes in identifying tissue damage?

To identify the site of tissue damage

Which enzyme is associated with hepatic disorders and viral hepatitis?

Alanine transaminase (ALT)

What is the primary difference between isoenzymes?

Their genetic makeup

Which enzyme is commonly used as a marker for myocardial infarction?

Creatine kinase (CK)

What is the primary purpose of enzyme markers in clinical diagnosis?

To diagnose diseases and disorders

What occurs to the cells of the affected region in myocardial infarction?

They release their enzyme content to the systematic circulation

What is the result of enzyme induction?

Increase in enzyme production

Which of the following enzymes is commonly used as a marker for liver function?

Glutamyl Transferase (GT)

What is the site of increased activity of ϒ–glutamyltransferase in response to ethanol intake?

Liver

Which of the following enzymes is specific to the prostate?

Acid Phosphatase (ACP)

What is the clinical application of Aspartate Amino transferase (AST) and Alanine Amino transferase (ALT)?

Diagnosis of liver disorders

What is the purpose of using a second enzyme in enzymatic assays?

To act on the product of the enzyme of primary interest

What is the coenzyme used by the second enzyme in enzymatic assays?

NADH

What is the wavelength at which the oxidation of NADH can be measured?

340nm

Why do healthy individuals have a constant level of enzymes in their plasma?

Because the rate of release from damaged cells is balanced by the rate of removal from the plasma

What is the significance of increased plasma levels of certain enzymes in disease diagnosis?

It indicates tissue damage to a specific tissue

What can cause an increase in the release of intracellular enzymes into the plasma?

A direct attack on the cell membranes by viruses or organic chemicals

This quiz covers various enzyme markers, their abbreviations, and their clinical significance in different disorders and metabolism. It includes acid phosphatase, alkaline phosphatase, alanine transaminase, and many more.

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