Enteric Nervous System Quiz

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Questions and Answers

What role do sensory neurons in the myenteric plexus play in the enteric nervous system?

  • They transmit impulses exclusively to the brain.
  • They connect sensory and motor neurons directly.
  • They measure the degree of stretch in smooth muscles. (correct)
  • They regulate mucus release into the lumen.

What is the primary function of the submucosal plexus in the enteric nervous system?

  • To measure the degree of stretch in smooth muscles.
  • To measure the chemical composition of the lumen. (correct)
  • To coordinate contraction of the smooth muscles.
  • To promote peristaltic movement in the gut.

How does the enteric nervous system function regarding brain input?

  • It relies entirely on sympathetic neuron input.
  • It operates independently but receives some regulatory input. (correct)
  • It does not interact with the autonomic nervous system.
  • It functions solely based on brain signals.

What type of neurons are specifically involved in coordinating peristaltic movement within the enteric nervous system?

<p>Visceromotor neurons. (C)</p> Signup and view all the answers

Which anatomical structure is located between the longitudinal and circular smooth muscle layers?

<p>Myenteric plexus. (B)</p> Signup and view all the answers

What percentage of postganglionic neurons release noradrenaline as a neurotransmitter?

<p>90% (B)</p> Signup and view all the answers

Which neurotransmitter is primarily used by postganglionic neurons that project to sweat glands?

<p>Acetylcholine (C)</p> Signup and view all the answers

Which cranial nerve is associated with the oculomotor nerve?

<p>III (A)</p> Signup and view all the answers

Where are most preganglionic parasympathetic neurons located?

<p>Cranial nerves and sacral spinal cord (C)</p> Signup and view all the answers

Postganglionic parasympathetic neurons typically have what kind of axons?

<p>Short and non-myelinated (D)</p> Signup and view all the answers

Which cranial nerve does NOT have postganglionic neurons located in discrete ganglia near their target organs?

<p>X (A)</p> Signup and view all the answers

What distinguishes the sympathetic nervous system ganglia location from the parasympathetic system?

<p>Sympathetic ganglia are close to the spinal cord. (D)</p> Signup and view all the answers

What roles do cranial nerves VII and IX primarily play in the parasympathetic nervous system?

<p>Tear production and salivation (C)</p> Signup and view all the answers

What primary function does the autonomic nervous system contribute to in the body?

<p>Maintenance of homeostasis (A)</p> Signup and view all the answers

What is the main role of the sympathetic division of the autonomic nervous system?

<p>Prepare the body for stressful situations (C)</p> Signup and view all the answers

Which of the following is not a parameter regulated by homeostasis?

<p>Growth rate (D)</p> Signup and view all the answers

How are preganglionic and postganglionic neurons characterized in the sympathetic nervous system?

<p>Preganglionic are short and lightly myelinated, postganglionic are long and non-myelinated (C)</p> Signup and view all the answers

What effect does the parasympathetic nervous system have on heart rate?

<p>Decreases heart rate (A)</p> Signup and view all the answers

Where are the preganglionic neuron cell bodies of the sympathetic nervous system located?

<p>Spinal cord between T1 and L2 (B)</p> Signup and view all the answers

Which neurotransmitter is released by preganglionic neurons in the sympathetic nervous system?

<p>Acetylcholine (C)</p> Signup and view all the answers

What is the primary role of the enteric division of the autonomic nervous system?

<p>Management of gut motility and secretion (A)</p> Signup and view all the answers

What pathway does a preganglionic neurone take when traveling to synapse with a postganglionic neurone in the sympathetic chain?

<p>Ventral rootlets (A)</p> Signup and view all the answers

Which type of sympathetic ganglia targets the abdomen or pelvis?

<p>Celiac ganglia (D)</p> Signup and view all the answers

What is the primary function of post-ganglionic sympathetic neurones in the cervical ganglion?

<p>Cause pupil dilation (B)</p> Signup and view all the answers

Which of the following describes the action of sympathetic post-ganglionic neurones on heart function?

<p>Increase heart rate and cause dilation of coronary arteries (A)</p> Signup and view all the answers

What is the role of the white ramus in the sympathetic nervous system?

<p>Connection between preganglionic and postganglionic fibres (C)</p> Signup and view all the answers

Which ramus ultimately leads to the target of a postganglionic neurone after passing through the sympathetic chain?

<p>Grey ramus (C)</p> Signup and view all the answers

What physiological reaction does the sympathetic nervous system primarily initiate?

<p>Pupil dilation and blood vessel constriction (A)</p> Signup and view all the answers

What is the primary role of the sympathetic trunk below the upper lumbar levels?

<p>Integrate and relay sympathetic signals throughout the body (C)</p> Signup and view all the answers

What role do visceral sensory neurons play in the autonomic nervous system?

<p>They provide sensory feedback to regulate autonomic activity. (C)</p> Signup and view all the answers

Which ganglion is associated with cranial nerve IX?

<p>Petrosal ganglion (A)</p> Signup and view all the answers

Which region of the nucleus of the solitary tract (NST) is associated with taste sensation?

<p>Upper region (B)</p> Signup and view all the answers

How do visceral sensory neurons from dorsal root ganglion (DRG) neurons reach the nucleus of the solitary tract?

<p>By projecting axons into deeper layers of the dorsal horn and crossing the midline (A)</p> Signup and view all the answers

What impact does the processing of visceral sensory information have on the autonomic nervous system?

<p>It modulates the output of postganglionic neurons. (A)</p> Signup and view all the answers

Where is most visceral sensory information primarily sent within the brain?

<p>To the nucleus of the solitary tract in the medulla (B)</p> Signup and view all the answers

What is the function of the nucleus of the solitary tract (NST) in relation to autonomic activity?

<p>It relays processing information to preganglionic ANS neurons. (B)</p> Signup and view all the answers

Which neurotransmitters are primarily involved in the signaling pathways of the autonomic nervous system?

<p>Ach, serotonin, dopamine, neuropeptides, and NO (D)</p> Signup and view all the answers

What is the primary function of the adrenal medulla during the fight or flight response?

<p>Stimulates the release of adrenaline and noradrenaline (B)</p> Signup and view all the answers

Which cranial nerve is associated with the otic ganglion that innervates the parotid salivary gland?

<p>Cranial nerve IX (B)</p> Signup and view all the answers

What roles do the different adrenergic receptor types play?

<p>They induce different intracellular signaling pathways (C)</p> Signup and view all the answers

Which G-protein-coupled receptor type is responsible for breaking down lipids in adipose tissue?

<p>G<del>s</del> (A)</p> Signup and view all the answers

What is the role of phospholipase C in adrenergic receptor signaling?

<p>Converts phosphatidylinositol-4,5-bisphosphate into second messengers (D)</p> Signup and view all the answers

What neurotransmitters are primarily associated with the autonomic nervous system's sympathetic actions?

<p>Adrenaline and noradrenaline (C)</p> Signup and view all the answers

Which of the following best describes the nature of adrenergic receptors?

<p>They are G-protein-coupled receptors (A)</p> Signup and view all the answers

Which statement accurately reflects the effects of adrenaline and noradrenaline binding to adrenergic receptors?

<p>Different receptors can lead to varying effects from the same neurotransmitter (D)</p> Signup and view all the answers

Flashcards

What is Homeostasis?

The physiological process that maintains internal systems at equilibrium despite external changes.

Autonomic Nervous System

The autonomic nervous system (ANS) is a part of the peripheral nervous system that controls involuntary bodily functions like heart rate, digestion, and breathing.

Sympathetic Nervous System

The sympathetic nervous system activates the 'fight or flight' response, preparing the body for stressful situations.

Parasympathetic Nervous System

The parasympathetic nervous system is responsible for 'rest and digest' functions, promoting relaxation and recovery.

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Enteric Nervous System

The enteric nervous system (ENS) is a part of the autonomic nervous system that controls the gastrointestinal tract.

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Sympathetic Nervous System Relay

The sympathetic nervous system uses a two-neuron relay system: preganglionic and postganglionic neurons.

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Preganglionic Neuron

The preganglionic neuron is located in the spinal cord and releases acetylcholine (Ach) as a neurotransmitter.

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Postganglionic Neuron

The postganglionic neuron is located outside the spinal cord and is responsible for releasing neurotransmitters to target organs.

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What is the primary neurotransmitter released by postganglionic sympathetic neurons?

The majority (90%) of postganglionic neurons in the sympathetic nervous system release this neurotransmitter, which prepares the body for 'fight or flight' responses.

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What are the postganglionic neurons that release acetylcholine in the sympathetic nervous system called?

These neurons represent a smaller portion (10%) of the postganglionic sympathetic nervous system and primarily target sweat glands and piloerector muscles.

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What are piloerector muscles?

These muscles attach to the hairs in our skin and when they contract, they cause the hair to stand on end.

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Which cranial nerves are associated with parasympathetic preganglionic neurons?

The majority of parasympathetic preganglionic neurons are located in the visceral efferent motor nuclei of these specific cranial nerves.

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Where are the parasympathetic preganglionic neurons located in the spinal cord?

These preganglionic neurons are located in the lateral grey matter of the sacral spinal cord.

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What are the characteristics of preganglionic parasympathetic axons?

They are long and lightly myelinated, allowing for faster transmission of signals to target organs.

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What is the neurotransmitter released by postganglionic parasympathetic neurons?

They release acetylcholine as a neurotransmitter, promoting the 'rest and digest' response.

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What are the routes taken by preganglionic sympathetic axons?

The sympathetic nervous system uses these pathways to connect the spinal cord to the ganglia where preganglionic neurons synapse.

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What is the sympathetic chain?

The sympathetic chain is a series of interconnected ganglia located along the vertebral column, from the cervical region to the coccyx.

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What are splanchnic nerves?

The splanchnic nerves are bundles of preganglionic sympathetic axons that originate from the thoracic and lumbar spinal cord and project to the prevertebral ganglia.

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What are prevertebral ganglia?

The prevertebral ganglia are located in the abdominal cavity and innervate organs in the abdomen and pelvis. Examples include the celiac, superior mesenteric, and inferior mesenteric ganglia.

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Where does the sympathetic chain extend?

The sympathetic chain extends beyond the lumbar region, even though preganglionic neurons are only found in the thoracic and upper lumbar levels.

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What is the white ramus?

The white ramus is a short myelinated fiber tract that carries preganglionic sympathetic axons from the spinal nerve to the sympathetic chain ganglia.

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What is the grey ramus?

The grey ramus carries postganglionic sympathetic axons from the sympathetic chain ganglia back to the spinal nerve, allowing them to reach their target organs.

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How does the sympathetic nervous system affect the eye?

Sympathetic activity can cause pupil dilation in the eye and eyelid retraction, allowing more light into the eye during a 'fight or flight' response.

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How does the sympathetic nervous system affect saliva?

Postganglionic sympathetic neurons increase the viscosity of saliva, but don't change the volume of saliva production.

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Where is the myenteric plexus located?

The myenteric plexus is located between the circular and longitudinal smooth muscle layers of the gut, and is involved in regulating peristalsis by coordinating the contraction and relaxation of the smooth muscles.

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Where is the submucosal plexus located?

The submucosal plexus is found within the submucosa of the gut wall and plays a role in regulating the chemical composition of the lumen, including secretion of mucus and other digestive juices

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What do the sensory neurons in the myenteric plexus respond to?

Sensory neurons in the myenteric plexus monitor the degree of stretch in the longitudinal and circular smooth muscles, providing information about the distention of the gut wall.

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What do the sensory neurons in the submucosal plexus respond to?

Sensory neurons in the submucosal plexus detect the chemical composition of the lumen, providing information about the contents of the gut and triggering appropriate responses.

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How independent is the enteric nervous system?

The enteric nervous system is capable of functioning largely independently of the brain, but it also receives regulatory input from the parasympathetic and sympathetic nervous systems.

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Adrenal Medulla

A part of the adrenal gland that releases adrenaline and noradrenaline into the bloodstream, primarily in response to stress or 'fight or flight' situations.

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Sympathetic Neurotransmitters

The sympathetic nervous system primarily uses acetylcholine (ACh) as a neurotransmitter at the preganglionic synapse and noradrenaline (NA) at the postganglionic synapse.

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Adrenergic Receptors

A type of G-protein coupled receptor (GPCR) that binds to adrenaline and noradrenaline, triggering a cascade of intracellular signaling pathways in target cells.

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α1 Adrenergic Receptor

A specific type of adrenergic receptor (α1) that activates phospholipase C, leading to an increase in intracellular calcium levels and smooth muscle contraction.

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β2 Adrenergic Receptor

A specific type of adrenergic receptor (β2) that binds to adrenaline and noradrenaline, leading to relaxation of smooth muscle in bronchioles, increasing airway diameter.

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β1 Adrenergic Receptor

Adrenaline/noradrenaline binding to β1 adrenergic receptors increases heart rate and contractility, resulting in increased blood flow throughout the body.

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α2 Adrenergic Receptor

Adrenaline/noradrenaline binding to α2 adrenergic receptors inhibits the release of neurotransmitters from presynaptic nerve terminals, decreasing sympathetic activity.

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Lipolysis

The specific enzyme involved in the breakdown of lipids (fats) stored in adipose tissue, a process known as lipolysis.

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What are visceral sensory neurons?

Visceral sensory neurons are specialized nerve cells that transmit information about the internal organs and systems to the central nervous system.

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Where are visceral sensory neurons located?

The dorsal root ganglia (DRG) are clusters of nerve cell bodies located in the spinal cord and contain visceral sensory neurons that relay information about the internal organs.

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What are afferent neurons?

Afferent neurons, also known as sensory neurons, carry signals from the periphery towards the central nervous system.

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What is the nucleus of the solitary tract (NST)?

The nucleus of the solitary tract (NST) is a group of neurons in the brainstem that receives and processes information from the internal organs, including taste, blood pressure, and heart rate.

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How does the NST receive information?

The NST receives information from visceral sensory neurons in the medulla, where it processes and relays this information to other parts of the brain and nervous system.

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How does the autonomic nervous system use visceral sensory information?

The autonomic nervous system is responsible for controlling involuntary bodily functions like heart rate, digestion, and breathing. Visceral sensory information plays a crucial role in regulating this system.

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How does sensory feedback regulate the autonomic nervous system?

Visceral sensory information is processed by the NST, which sends signals to the autonomic nervous system, influencing the activity of preganglionic neurons in the brainstem and spinal cord.

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What do preganglionic neurons do?

The preganglionic neurons are located in the brainstem and spinal cord and send signals to the autonomic ganglia, which are clusters of nerve cells located outside the central nervous system.

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Study Notes

Autonomic Nervous System Organization

  • The autonomic nervous system (ANS) regulates internal body functions to maintain homeostasis.
  • Homeostasis is the physiological process keeping internal body systems in equilibrium despite external changes.

Examples of Homeostatically Regulated Parameters

  • Body temperature
  • Blood pressure
  • Hydration levels
  • Acid-base balance

Autonomic Nervous System Structure

  • The ANS is involuntary; we have no conscious control over its actions.
  • It has three divisions: sympathetic, parasympathetic, and enteric.

Sympathetic Nervous System

  • Active Division ("fight or flight"): involved in active or stressful situations.
  • Increased heart rate: enhances blood flow to muscles.
  • Pupil dilation: allows more light into the eyes.
  • Bronchodilation: increases air intake.
  • Redirected blood flow: prioritizes striated and cardiac muscles.
  • Neurotransmitter: primarily norepinephrine (noradrenaline), with some acetylcholine use in sweat glands and piloerector muscles.

Parasympathetic Nervous System

  • Passive division ("rest and digest"): involved in maintaining the body's everyday functions.
  • Decreased heart rate: conserves energy.
  • Pupil constriction: reduces light intake.
  • Bronchoconstriction: reduces air intake.
  • Blood flow redirection: directs blood to internal organs.
  • Neurotransmitter: acetylcholine.

Enteric Nervous System

  • Embedded in the digestive tract lining.
  • Regulates gut motility and secretions such as:
    • Increased motility (peristalsis)
    • Mucus secretion
    • Digestive enzyme secretion

Sympathetic Nervous System Pathway

  • Two-neuron relay: preganglionic and postganglionic neurons.
  • Preganglionic neurons originate in the spinal cord (T1-L2).
  • They project to ganglia (paravertebral or prevertebral)
  • Postganglionic neurons project to target tissues (smooth muscle, glands, cardiac muscle).
  • Primarily releases norepinephrine (noradrenaline) as a neurotransmitter.

Parasympathetic Nervous System Pathway

  • Two-neuron relay: preganglionic and postganglionic neurons.
  • Preganglionic neurons in the brain stem (cranial nerves III, VII, IX, X) and sacral spinal cord (S2-S4).
  • Postganglionic neurons are located in ganglia close to or within target organs.
  • Primarily releases acetylcholine as a neurotransmitter.

ANS Neurotransmitters

  • Sympathetic: norepinephrine (primarily) and (occasionally) acetylcholine.
  • Parasympathetic: acetylcholine.

Multiple Receptors

  • Multiple types of receptors for neurotransmitters (e.g., adrenergic and cholinergic receptors) lead to various effects on target tissues. Receptor type determines extent of effect.

Enteric Nervous System Organization

  • The enteric nervous system (ENS) contains sensory (stretch, chemical), interneurons, and autonomic motor (visceromotor) neurons.
  • Controls peristalsis (gut movement
  • Regulates secretions

Regulation of ANS Activity

  • Sensory feedback from target tissues regulates ANS activity.
  • Visceral sensory neurons carry sensory information to brainstem nuclei that modulate ANS activity.
  • Higher brain areas also influence the ANS.

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