Energy Transfer in Biological Work

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Questions and Answers

What is the primary role of high-energy phosphates in biological work?

  • To buffer lactic acid production
  • To provide energy for cellular processes (correct)
  • To facilitate the breakdown of fatty acids
  • To store excess glucose

During a sprint lasting less than 10 seconds, which energy system is predominantly utilized?

  • ATP-PCr system (correct)
  • Glycolytic system
  • Aerobic system
  • Beta-oxidation

Which of the following is a major function of carbohydrates in energy metabolism?

  • Serving as the main fuel source for high-intensity exercise (correct)
  • Providing building blocks for protein synthesis
  • Facilitating the transport of oxygen in the blood
  • Acting as a primary component of cell membranes

How does increased exercise intensity affect lactate formation and accumulation?

<p>It increases both lactate formation and accumulation (A)</p> Signup and view all the answers

What is the principal role of the citric acid cycle in energy metabolism?

<p>To produce CO2 and hydrogen atoms for further ATP production (A)</p> Signup and view all the answers

Which of the following describes a general pathway for energy release during macronutrient catabolism?

<p>Breakdown of macronutrients into smaller units, then into acetyl coenzyme A (C)</p> Signup and view all the answers

How does ATP yield from the catabolism of a molecule of carbohydrate compare to that of a molecule of lipid?

<p>Lipid yields significantly more ATP than carbohydrate (A)</p> Signup and view all the answers

Which metabolic process allows for interconversions among carbohydrate, lipid, and protein?

<p>Citric acid cycle (A)</p> Signup and view all the answers

What two contributions do high-energy phosphates provide for powering biological work?

<p>Energy transfer and muscle contraction (A)</p> Signup and view all the answers

What are the three stages that lead to the release and energy conservation by cells for biological work?

<p>Digestion, degradation to acetyl-CoA, and oxidation in the citric acid cycle (A)</p> Signup and view all the answers

Which feature of ATP allows it to serve as the 'energy currency' of the cell?

<p>The high energy released upon hydrolysis of its phosphate bonds (D)</p> Signup and view all the answers

How does phosphocreatine (PCr) facilitate ATP resynthesis during intense exercise?

<p>By directly donating a phosphate group to ADP (D)</p> Signup and view all the answers

Why is the anaerobic energy system important during high-intensity exercise?

<p>It can produce ATP quickly without oxygen (C)</p> Signup and view all the answers

Three factors regulate glycolysis; which of the options listed is NOT one of them?

<p>The levels of ATP (B)</p> Signup and view all the answers

What role does hormone-sensitive lipase play in fat mobilization?

<p>It stimulates the breakdown of triacylglycerols into glycerol and fatty acids (C)</p> Signup and view all the answers

What is the function of the citric acid cycle in the context of the metabolic mill?

<p>To provide a central link between macronutrient energy and chemical energy in ATP (B)</p> Signup and view all the answers

How does a high-carbohydrate diet affect protein utilization during exercise?

<p>It decreases protein breakdown, sparing muscle protein (A)</p> Signup and view all the answers

Under what conditions would protein become a more significant energy source during exercise?

<p>During ultra-endurance exercise when glycogen stores are depleted (D)</p> Signup and view all the answers

How does the location of ATP production differ between glycolysis and the citric acid cycle?

<p>Glycolysis occurs in the cytosol, while the citric acid cycle occurs in the mitochondria (A)</p> Signup and view all the answers

How does exercise affect hormonal release and its subsequent effect on fat mobilization?

<p>It increases hormonal release, which stimulates adipose tissue lipolysis (B)</p> Signup and view all the answers

In anaerobic glycolysis, what is the end product of glucose breakdown, and what happens to it?

<p>Pyruvate, which is converted to lactate (D)</p> Signup and view all the answers

Which energy substrate provides the most ATP molecules upon complete oxidation?

<p>Fatty acid (C)</p> Signup and view all the answers

What is the primary function of carbohydrate in energy metabolism?

<p>Immediate energy for high-intensity work (C)</p> Signup and view all the answers

What is the primary fate of pyruvate during anaerobic glycolysis?

<p>Conversion to lactate. (D)</p> Signup and view all the answers

What conditions need to be met to operate at steady-rate during physical activity?

<p>Oxygen supply must equal oxygen demand. (A)</p> Signup and view all the answers

How do scientists define maximal oxygen consumption, or VO2max?

<p>When oxygen uptake increases slightly with additional increases in exercise intensity (B)</p> Signup and view all the answers

What term describes bodily processes that do not immediately return to resting levels after physical activity?

<p>Oxygen Consumption During Recovery (A)</p> Signup and view all the answers

What characterizes blood lactate accumulation during exercise?

<p>It rises exponentially at specific point of exercise. (C)</p> Signup and view all the answers

Why do endurance-trained individuals have a higher percentage of what they can sustain comfortably, in steady-state?

<p>Specific genetic endowment, adaptations, rapid removal (A)</p> Signup and view all the answers

How is the energy for exercise created?

<p>Through overlapping means. (A)</p> Signup and view all the answers

What facilitates aerobic metabolism for athletes?

<p>Rapid muscular bioenergetics and overall blood flow. (B)</p> Signup and view all the answers

Why might a doctor recommend moderate intensity, 'active recovery' ?

<p>Because light movement facilitates recovery more than being passive. (C)</p> Signup and view all the answers

Why should athletes maintain appropriate stores of glycogen?

<p>To preserve central nervous system function. (A)</p> Signup and view all the answers

Which of the following is NOT part of what steady-rate exercise replenishes?

<p>Brain activity. (A)</p> Signup and view all the answers

Why might blood lactate accumulate?

<p>When lactate created in a muscular setting exceeeds a removal rate. (C)</p> Signup and view all the answers

What is the relationship between energy consumption, rest, and exercise?

<p>Energy exceeds VO2 unless the oxygen deficit is met at a steady rate. (D)</p> Signup and view all the answers

If not enough glycogen is present, will athletes be able to perform at their peak?

<p>No, they must preserve adequate glycogen to power their activity. (B)</p> Signup and view all the answers

Why does the body primarily rely on phosphocreatine (PCr) for ATP resynthesis during short bursts of maximal activity?

<p>PCr breakdown does not depend on a supply of oxygen and it liberates energy without a long series of reactions. (A)</p> Signup and view all the answers

During intense exercise, why would an athlete's pyruvate predominantly convert to lactate instead of entering the aerobic pathways?

<p>To regenerate NAD+ allowing glycolysis to continue. (A)</p> Signup and view all the answers

How does the total ATP production from fat catabolism compare to that of carbohydrate catabolism, given equal weights of each?

<p>Fats yield more ATP due to their greater number of carbon atoms. (D)</p> Signup and view all the answers

How does the process of deamination enable protein to be used as an energy substrate?

<p>It modifies the protein structure so the carbon skeleton can enter metabolic pathways. (D)</p> Signup and view all the answers

What is the primary function of the citric acid cycle (Krebs cycle) in energy metabolism?

<p>To generate hydrogen atoms for further ATP production in the electron transport chain. (C)</p> Signup and view all the answers

How does a small oxygen deficit benefit an endurance-trained athlete at the start of exercise?

<p>It allows them to reach steady-rate oxygen consumption more quickly. (A)</p> Signup and view all the answers

What is the main reason blood lactate accumulates during high-intensity exercise?

<p>The production rate of lactate exceeds the rate at which it can be cleared. (C)</p> Signup and view all the answers

How does hormonal release during exercise support fat mobilization from adipose tissue?

<p>By stimulating hormone-sensitive lipase to break down triacylglycerols. (A)</p> Signup and view all the answers

Why are fatty acids unable to directly undergo metabolic interconversions to produce glucose?

<p>Fatty acids require intermediates generated during carbohydrate breakdown to enter the metabolic mill. (C)</p> Signup and view all the answers

How does increased blood perfusion through the liver, heart, and ventilatory muscles aid an athlete?

<p>Increased blood flow accelerates blood lactate removal. (C)</p> Signup and view all the answers

How do endurance-trained individuals typically compare to untrained individuals in terms of their blood lactate threshold?

<p>Trained individuals have a higher blood lactate threshold. (C)</p> Signup and view all the answers

What primarily limits prolonged steady-rate aerobic exercise?

<p>Fluid loss, electrolyte depletion, and glycogen depletion (A)</p> Signup and view all the answers

In what way does ‘active recovery’ facilitate recovery, when compared to passive procedures?

<p>It helps you maintain performance and facilitates recovery compared with passive rest. (B)</p> Signup and view all the answers

Why is maintaining adequate glycogen stores crucial for athletes aiming to optimize their potential for steady-rate exercise?

<p>Glycogen stores ensure a consistent supply of glucose, vital for nervous system function and muscle energy. (C)</p> Signup and view all the answers

How does steady-rate exercise assist in the restoration of the body's physiological state?

<p>It is a low energy cost, but steadily resynthesizes high-energy phosphates; and can replenish O2 levels.. (B)</p> Signup and view all the answers

Flashcards

What is ATP?

ATP is formed from adenosine linked to three phosphates.

What forms ADP?

Adenosine diphosphate (ADP) is formed when ATP joins with water, catalyzed by the enzyme adenosine triphosphatase (ATPase).

Why resynthesize ATP?

Cells contain small ATP quantities, so ATP must continually be resynthesized.

Where does ATP resynthesis come from?

Some energy for ATP resynthesis comes from anaerobic splitting of a phosphate from PCr.

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Stages of energy release?

Three stages that lead to release and energy conservation by cells for biologic work: Digestion, amino acid degradation, acetyl-coenzyme A degradation

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Name a macronutrient fuel source

These are triacylglycerol and glycogen molecules, blood glucose, free fatty acids, intramuscular- and liver-derived carbon skeletons of amino acids, anaerobic reactions, PCr phosphorylates ADP

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What is the Aerobic System?

Aerobic energy system describes oxygen-requiring energy reactions using CHO, lipid and protein.

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Anaerobic Energy System

Anaerobic energy system generates energy rapidly for short durations using lactic acids and alactic acids.

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Energy from carbohydrates?

Carbohydrate's primary function supplies energy for cellular work.

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Anaerobic Glycolysis

Anaerobic (rapid) glycolysis results in pyruvate-to-lactate formation, releasing about 5% of energy.

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Aerobic Glycolysis

Aerobic (slow) glycolysis results in pyruvate-to-acetyl-CoA-to-citric acid cycle and electron transport.

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Name an enzyme that regulates glycolysis.

Hexokinase, phosphorylase, phosphofructokinase, and pyruvate kinase are four key glycolytic enzymes.

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What forms from Lactic Acid?

Lactic acid forms during anaerobic glycolysis and dissociates to release a hydrogen ion (H+).

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Citric Acid Cycle role?

The citric acid cycle is the second stage of carbohydrate breakdown, producing CO2 and hydrogen atoms.

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Complete fat oxidation

Complete oxidation of a triacylglycerol molecule yields about 460 ATP molecules.

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Fat catabolism source?

There are three specific energy sources for fat catabolism: Triacylglycerols in muscle mitochondria, circulating triacylglycerols, and circulating free fatty acids.

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Lipase action in fat?

Hormone-sensitive lipase stimulates triacylglycerol (TAG) breakdown into its components.

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Protein's role in ATP?

After deamination, the remaining carbon skeleton enters metabolic pathways to produce ATP aerobically.

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Cycle's role?

Citric acid cycle provides energy from macronutrients and chemical energy in ATP.

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Protein major energy source?

Protein is not a major energy source during exercise, except in ultra-endurance events.

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High-intensity fuel?

High-intensity exercise uses intramuscular ATP and PCr for energy.

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Short term energy?

Energy comes mainly from muscle glycogen breakdown via anaerobic glycolysis in intense exercise.

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Lactate threshold?

Blood lactate threshold occurs when muscle cells can't meet energy demands aerobically and can't oxidize lactate fast enough.

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Long-term energy?

Aerobic metabolism provides most energy for exercise lasting several minutes.

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VO2 during exercise?

Oxygen uptake rises exponentially, plateaus, and remains steady during exercise.

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Reaching steady rate?

Endurance-trained individuals reach steady rate faster than untrained.

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VO2max defined?

VO2max is when oxygen uptake plateaus with increased exercise intensity.

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After exercise?

Bodily processes don't immediately return to resting levels after physical activity.

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Recovery VO2 curve?

Recovery VO2 follows a curve, decreasing by about 50% over each 30-second period.

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Steady rate Recovery?

Steady-rate exercise recovery involves resynthesis of high-energy phosphates.

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