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Questions and Answers
What role does ATP play in cells?
What role does ATP play in cells?
What percentage of proteins, on average, binds ATP?
What percentage of proteins, on average, binds ATP?
Which of the following statements about enzymes is correct?
Which of the following statements about enzymes is correct?
What is meant by the term 'activation energy'?
What is meant by the term 'activation energy'?
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How do enzymes affect the rate of chemical reactions?
How do enzymes affect the rate of chemical reactions?
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What characterizes anabolic pathways in metabolism?
What characterizes anabolic pathways in metabolism?
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What is produced during the breakdown of proteins?
What is produced during the breakdown of proteins?
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Which process directly transfers a phosphate group to ADP to form ATP?
Which process directly transfers a phosphate group to ADP to form ATP?
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What role do electron carriers play in cellular respiration?
What role do electron carriers play in cellular respiration?
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Which of the following statements about catabolic pathways is correct?
Which of the following statements about catabolic pathways is correct?
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Is the reaction of yeast and flour leading to fermentation spontaneous or non-spontaneous?
Is the reaction of yeast and flour leading to fermentation spontaneous or non-spontaneous?
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What is the value of ΔG for a spontaneous reaction?
What is the value of ΔG for a spontaneous reaction?
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What does the hydrolysis of ATP signify in terms of spontaneity?
What does the hydrolysis of ATP signify in terms of spontaneity?
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How can a non-spontaneous reaction become thermodynamically favored?
How can a non-spontaneous reaction become thermodynamically favored?
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In the coupled reaction involving glucose and ATP, what is the net ΔG?
In the coupled reaction involving glucose and ATP, what is the net ΔG?
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What role does ATP play in cellular processes?
What role does ATP play in cellular processes?
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Which of the following changes will result in a non-spontaneous reaction?
Which of the following changes will result in a non-spontaneous reaction?
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What is the impact of coupling an endergonic reaction with an exergonic reaction?
What is the impact of coupling an endergonic reaction with an exergonic reaction?
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What type of energy is associated with an object's motion?
What type of energy is associated with an object's motion?
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Which law states that energy cannot be created or destroyed, only transformed?
Which law states that energy cannot be created or destroyed, only transformed?
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What type of reaction requires a continuous input of energy to proceed?
What type of reaction requires a continuous input of energy to proceed?
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Which of the following is true about Gibbs free energy?
Which of the following is true about Gibbs free energy?
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What does an increase in entropy indicate about a system?
What does an increase in entropy indicate about a system?
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In the equation $ riangle G = riangle H - T riangle S$, what does $ riangle H$ represent?
In the equation $ riangle G = riangle H - T riangle S$, what does $ riangle H$ represent?
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Which form of energy is stored in the chemical bonds of substances?
Which form of energy is stored in the chemical bonds of substances?
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Which process is an example of a spontaneous reaction?
Which process is an example of a spontaneous reaction?
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Which type of energy is involved in moving charged particles?
Which type of energy is involved in moving charged particles?
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What happens to a system's energy during an increase in entropy according to the Second Law of Thermodynamics?
What happens to a system's energy during an increase in entropy according to the Second Law of Thermodynamics?
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What is the primary role of NAD+ and FAD in metabolic reactions?
What is the primary role of NAD+ and FAD in metabolic reactions?
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Which of the following best describes oxidation in metabolic reactions?
Which of the following best describes oxidation in metabolic reactions?
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What is the function of feedback inhibition in biochemical regulation?
What is the function of feedback inhibition in biochemical regulation?
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What is the main function of the proteasome in the cell?
What is the main function of the proteasome in the cell?
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What process enables cells to recycle worn-out organelles?
What process enables cells to recycle worn-out organelles?
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How does cellular regulation primarily function in metabolic pathways?
How does cellular regulation primarily function in metabolic pathways?
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What is the significance of ubiquitin in protein recycling?
What is the significance of ubiquitin in protein recycling?
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What is the role of hydrolases found in lysosomes?
What is the role of hydrolases found in lysosomes?
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What is the primary function of enzymes in biological reactions?
What is the primary function of enzymes in biological reactions?
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What occurs during ATP hydrolysis in terms of energy?
What occurs during ATP hydrolysis in terms of energy?
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Which statement correctly describes how enzymes function?
Which statement correctly describes how enzymes function?
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How does ATP contribute to the energy needs of a typical cell?
How does ATP contribute to the energy needs of a typical cell?
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What is the significance of activation energy in a chemical reaction?
What is the significance of activation energy in a chemical reaction?
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What characterizes anabolic pathways in metabolism?
What characterizes anabolic pathways in metabolism?
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Which process is associated with substrate-level phosphorylation?
Which process is associated with substrate-level phosphorylation?
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What type of reaction is involved in the breakdown of proteins?
What type of reaction is involved in the breakdown of proteins?
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How do electron carriers such as NAD+ and FAD function in metabolic processes?
How do electron carriers such as NAD+ and FAD function in metabolic processes?
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What is the role of ATP in anabolic reactions?
What is the role of ATP in anabolic reactions?
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What indicates that a reaction is spontaneous?
What indicates that a reaction is spontaneous?
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What is the ΔG value of ATP hydrolysis, indicating its spontaneity?
What is the ΔG value of ATP hydrolysis, indicating its spontaneity?
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Which statement best describes an endergonic reaction?
Which statement best describes an endergonic reaction?
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Which reaction demonstrates a coupled process involving ATP?
Which reaction demonstrates a coupled process involving ATP?
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What is the relationship between exergonic reactions and ΔG?
What is the relationship between exergonic reactions and ΔG?
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How can a non-spontaneous reaction become favored thermodynamically?
How can a non-spontaneous reaction become favored thermodynamically?
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In the context of cellular processes, what does 'coupled reaction' refer to?
In the context of cellular processes, what does 'coupled reaction' refer to?
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What is the significance of ΔG being negative in a coupled reaction involving glucose and ATP?
What is the significance of ΔG being negative in a coupled reaction involving glucose and ATP?
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What is the definition of chemical reactions?
What is the definition of chemical reactions?
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Which of the following best describes kinetic energy?
Which of the following best describes kinetic energy?
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What does the First Law of Thermodynamics state?
What does the First Law of Thermodynamics state?
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Which component of the Gibbs free energy equation represents the total energy of a system?
Which component of the Gibbs free energy equation represents the total energy of a system?
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What is the primary outcome of an increase in entropy according to the Second Law of Thermodynamics?
What is the primary outcome of an increase in entropy according to the Second Law of Thermodynamics?
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What type of energy is involved in chemical processes like combustion?
What type of energy is involved in chemical processes like combustion?
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What is the effect of activation energy on spontaneous reactions?
What is the effect of activation energy on spontaneous reactions?
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Which reaction type requires energy input to drive the process forward indefinitely?
Which reaction type requires energy input to drive the process forward indefinitely?
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What is the significance of changes in free energy when predicting chemical reactions?
What is the significance of changes in free energy when predicting chemical reactions?
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Which of the following is true regarding the recycling of organic molecules in metabolism?
Which of the following is true regarding the recycling of organic molecules in metabolism?
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What is the main purpose of gene regulation in metabolic pathways?
What is the main purpose of gene regulation in metabolic pathways?
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What occurs during oxidation in metabolic reactions?
What occurs during oxidation in metabolic reactions?
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How does feedback inhibition function in metabolic pathways?
How does feedback inhibition function in metabolic pathways?
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What is the function of ubiquitin in the cell?
What is the function of ubiquitin in the cell?
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What is autophagy?
What is autophagy?
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What are catabolic pathways primarily responsible for?
What are catabolic pathways primarily responsible for?
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What defines a biochemical regulation mechanism in metabolic pathways?
What defines a biochemical regulation mechanism in metabolic pathways?
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What are lysosomes primarily involved in?
What are lysosomes primarily involved in?
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Study Notes
Energy and Chemical Reactions
- Chemical reactions involve the transformation of substances by changes in the arrangement of atoms
- Matter is anything tangible that can be measured, existing in solid, liquid, and gaseous states
- Energy is the capacity to do work and exists in forms like chemical, electrical, mechanical, and radiant energy
- Thermodynamics studies how energy is converted from one form to another
- The First Law of Thermodynamics states that energy cannot be created or destroyed, only transformed
- The Second Law of Thermodynamics states that energy transformations increase entropy, leading to less usable energy
Free Energy
- Free energy (G) is the energy available to do work
- ΔG is the change in free energy during a reaction
- ΔG = ΔH - TΔS, where ΔH is enthalpy, T is temperature, and ΔS is entropy
- Exergonic reactions release energy (ΔG < 0) and are spontaneous
- Endergonic reactions require energy input (ΔG > 0) and are non-spontaneous
ATP and Energy Coupling
- ATP is the primary energy currency in cells, providing energy for endergonic reactions
- ATP hydrolysis is exergonic (releases energy) and is often coupled with endergonic reactions to make them spontaneous
- This coupling allows cells to use the energy from ATP breakdown to drive processes like biosynthesis and cellular work
Enzymes
- Enzymes are biological catalysts that speed up chemical reactions without being consumed
- They lower activation energy, the initial energy needed for a reaction to occur
- Enzymes bind to substrates at active sites to catalyze reactions
- Their names often end in "-ase"
Metabolism
- Metabolism encompasses all chemical reactions in a living organism
- Anabolic pathways synthesize cellular components, requiring energy input (endergonic)
- Catabolic pathways break down components releasing energy (exergonic)
Cellular Respiration and Electron Carriers
- Cellular respiration is a catabolic process that generates ATP
- Electrons are shuttled via electron carriers like NAD+ and FAD, which gain electrons to become NADH and FADH2
- These carriers play crucial roles in transferring electrons, which are then used to drive ATP synthesis
Redox Reactions
- Redox reactions involve the transfer of electrons
- Oxidation is the loss of electrons
- Reduction is the gain of electrons
Regulation of Metabolic Pathways
- Metabolic pathways are regulated to ensure efficient resource utilization
- Gene regulation controls the expression of genes encoding enzymes
- Cellular regulation involves signaling pathways and hormones
- Biochemical regulation utilizes feedback inhibition and regulation of rate-limiting steps
Recycling of Organic Molecules
- All living organisms recycle organic molecules to conserve energy
- Proteasomes are large complexes that break down proteins using proteases
- Ubiquitin tags target proteins for degradation by proteasomes
- Lysosomes contain hydrolases to break down various macromolecules
- Autophagy is a process where lysosomes digest worn-out organelles
Energy & Chemical Reactions
- Chemical reactions are processes where substances change into other substances.
- Bonds are energy relationships involving electrons.
- Matter can be changed physically or chemically.
- Energy is the ability to do work, exists in kinetic and potential forms.
- Chemical energy is stored in bonds of substances.
- Electrical energy is movement of charged particles.
- Mechanical energy directly involves moving matter
- Radiant energy travels in waves.
- Thermodynamics is the study of energy interconversions.
- The first law of thermodynamics states energy cannot be created or destroyed, only converted from one form to another.
- The second law of thermodynamics states the transfer of energy increases entropy (disorder) of a system.
- Free energy (G) is the amount of energy available for work and is calculated using the Gibbs free energy equation:
- ΔG = ΔH - TΔS
- ΔG = change in free energy
- ΔH = enthalpy or total energy
- T = absolute temperature in Kelvin
- ΔS = entropy
- ΔG = ΔH - TΔS
- Reactions with a negative ΔG are spontaneous (exergonic) and release energy.
- Reactions with a positive ΔG are nonspontaneous (endergonic) and require a continuous input of energy.
- ATP hydrolysis is an exergonic reaction that releases energy used by the cell
- ATP drives endergonic reactions through phosphorylation.
- Coupled reactions pair an endergonic reaction with an exergonic reaction to make the net process spontaneous.
- Cells use millions of ATP molecules per second to drive endergonic processes.
- Breakdown of food releases energy to synthesize ATP.
Enzymes
- Enzymes are biological catalysts that increase the rate of chemical reactions.
- Enzymes bind to substrates at the active site.
- Enzymes can be recognized by their "-ase" suffix, such as hydrolase.
- Activation energy is the initial input of energy required to start a reaction.
Overview of Metabolism
- Metabolic pathways involve a series of chemical reactions coordinated by enzymes.
- Anabolic pathways synthesize cellular components and are endergonic.
- Catabolic pathways break down cellular components and are exergonic.
- Catabolic pathways are regulated to break down molecules only when needed or when energy is required.
- Anabolic pathways are regulated to synthesize molecules only when needed.
Recycling of Organic Molecules
- Most large molecules have a short life span with a half-life - the time it takes for 50% of the molecule to be broken down.
- Organisms efficiently reuse and recycle organic molecules to save energy.
- The proteasome breaks down proteins using protease enzymes.
- Ubiquitin tags target proteins to be broken down in the proteasome.
- Lysosomes contain hydrolases to break down molecules and digest substances taken up by endocytosis.
- Autophagy is the recycling of worn out organelles using an autophagosome.
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Description
Test your knowledge on energy transformations and chemical reactions with this quiz. Explore concepts of thermodynamics, free energy, and the laws governing these processes. Challenge yourself with questions on exergonic and endergonic reactions.