Endoplasmic Reticulum Structure and Function
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Questions and Answers

What is the function of the endoplasmic reticulum (ER) in a eucaryotic cell?

  • Energy production
  • Protein biosynthesis (correct)
  • DNA replication
  • Cell division

Which organelles receive proteins initially delivered to the endoplasmic reticulum (ER) lumen?

  • Golgi apparatus and lysosomes (correct)
  • Vacuoles and chloroplasts
  • Mitochondria and peroxisomes
  • Nucleus and ribosomes

What marks proteins for translocation into the lumen of the endoplasmic reticulum (ER)?

  • Messenger RNA (mRNA)
  • Ribosomal RNA
  • Signal sequence (SS) (correct)
  • Transfer RNA (tRNA)

What is the internal space enclosed by the endoplasmic reticulum (ER) membrane called?

<p>ER lumen (D)</p> Signup and view all the answers

Which cellular organelles benefit from the ER membrane contribution?

<p>Golgi apparatus and mitochondria (A)</p> Signup and view all the answers

What happens to the signal sequence (SS) of a protein after it reaches its final destination?

<p>It is removed during transport or after reaching its destination. (A)</p> Signup and view all the answers

What is the purpose of the signal peptidase within the ER lumen?

<p>To remove the signal sequence from the polypeptide (C)</p> Signup and view all the answers

What role does the signal recognition particle (SRP) play in the protein targeting pathway?

<p>It binds to the SS emerging from the ribosome and halts elongation of the polypeptide (C)</p> Signup and view all the answers

Where does N-linked glycosylation predominantly take place?

<p>ER (B)</p> Signup and view all the answers

What happens to misfolded or incompletely assembled proteins in the ER?

<p>They are retained and transported back into the cytosol proteasomes (A)</p> Signup and view all the answers

What is the role of the peptide translocation complex in the ER?

<p>Interact directly with the ribosome to deliver the nascent polypeptide (D)</p> Signup and view all the answers

What is the function of dolichol phosphate in protein processing?

<p>Transfer a sugar-residue precursor to a specific asparagine residue (C)</p> Signup and view all the answers

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