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Endoplasmic Reticulum Structure and Function

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Endoplasmic Reticulum Structure and Function

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Questions and Answers

What is the function of the endoplasmic reticulum (ER) in a eucaryotic cell?

Energy production

Protein biosynthesis (correct)

DNA replication

Cell division

Which organelles receive proteins initially delivered to the endoplasmic reticulum (ER) lumen?

Golgi apparatus and lysosomes (correct)

Vacuoles and chloroplasts

Mitochondria and peroxisomes

Nucleus and ribosomes

What marks proteins for translocation into the lumen of the endoplasmic reticulum (ER)?

Messenger RNA (mRNA)

Ribosomal RNA

Signal sequence (SS) (correct)

Transfer RNA (tRNA)

What is the internal space enclosed by the endoplasmic reticulum (ER) membrane called?

ER lumen Signup and view all the answers

Which cellular organelles benefit from the ER membrane contribution?

Golgi apparatus and mitochondria Signup and view all the answers

What happens to the signal sequence (SS) of a protein after it reaches its final destination?

It is removed during transport or after reaching its destination. Signup and view all the answers

What is the purpose of the signal peptidase within the ER lumen?

To remove the signal sequence from the polypeptide Signup and view all the answers

What role does the signal recognition particle (SRP) play in the protein targeting pathway?

It binds to the SS emerging from the ribosome and halts elongation of the polypeptide Signup and view all the answers

Where does N-linked glycosylation predominantly take place?

ER Signup and view all the answers

What happens to misfolded or incompletely assembled proteins in the ER?

They are retained and transported back into the cytosol proteasomes Signup and view all the answers

What is the role of the peptide translocation complex in the ER?

Interact directly with the ribosome to deliver the nascent polypeptide Signup and view all the answers

What is the function of dolichol phosphate in protein processing?

Transfer a sugar-residue precursor to a specific asparagine residue Signup and view all the answers