Endoplasmic Reticulum Structure and Function
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Endoplasmic Reticulum Structure and Function

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Questions and Answers

What is the function of the endoplasmic reticulum (ER) in a eucaryotic cell?

  • Energy production
  • Protein biosynthesis (correct)
  • DNA replication
  • Cell division

    • Which organelles receive proteins initially delivered to the endoplasmic reticulum (ER) lumen?

  • Golgi apparatus and lysosomes (correct)
  • Vacuoles and chloroplasts
  • Mitochondria and peroxisomes
  • Nucleus and ribosomes

    • What marks proteins for translocation into the lumen of the endoplasmic reticulum (ER)?

  • Messenger RNA (mRNA)
  • Ribosomal RNA
  • Signal sequence (SS) (correct)
  • Transfer RNA (tRNA)

    • What is the internal space enclosed by the endoplasmic reticulum (ER) membrane called?

    <p>ER lumen</p> Signup and view all the answers

    Which cellular organelles benefit from the ER membrane contribution?

    <p>Golgi apparatus and mitochondria</p> Signup and view all the answers

    What happens to the signal sequence (SS) of a protein after it reaches its final destination?

    <p>It is removed during transport or after reaching its destination.</p> Signup and view all the answers

    What is the purpose of the signal peptidase within the ER lumen?

    <p>To remove the signal sequence from the polypeptide</p> Signup and view all the answers

    What role does the signal recognition particle (SRP) play in the protein targeting pathway?

    <p>It binds to the SS emerging from the ribosome and halts elongation of the polypeptide</p> Signup and view all the answers

    Where does N-linked glycosylation predominantly take place?

    <p>ER</p> Signup and view all the answers

    What happens to misfolded or incompletely assembled proteins in the ER?

    <p>They are retained and transported back into the cytosol proteasomes</p> Signup and view all the answers

    What is the role of the peptide translocation complex in the ER?

    <p>Interact directly with the ribosome to deliver the nascent polypeptide</p> Signup and view all the answers

    What is the function of dolichol phosphate in protein processing?

    <p>Transfer a sugar-residue precursor to a specific asparagine residue</p> Signup and view all the answers

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