Podcast
Questions and Answers
What does AKAP stand for in the context of the given text?
What does AKAP stand for in the context of the given text?
- Adenosine kinase anchoring proteins
- A kinase anchoring proteins (correct)
- Aromatic kinase anchoring proteins
- A kinase activating proteins
Which protein plays a dominant role in chronotropy and inotropy in normal heart cells?
Which protein plays a dominant role in chronotropy and inotropy in normal heart cells?
- PKA
- Adenylate cyclase
- $\beta1$AR (correct)
- $\beta2$AR
What does an inappropriate increase in sympathetic activity lead to?
What does an inappropriate increase in sympathetic activity lead to?
- Decreased heart rate
- Decreased contractility of the heart
- Increased heart rate (correct)
- Stabilization of heart function
Where do A kinase anchoring proteins (AKAP) localize b AR, PKA, PDEs, and Adenylate cyclase in cardiac muscle?
Where do A kinase anchoring proteins (AKAP) localize b AR, PKA, PDEs, and Adenylate cyclase in cardiac muscle?
Which receptor has a modest role in chronotropy but little role in inotropy in normal heart cells?
Which receptor has a modest role in chronotropy but little role in inotropy in normal heart cells?
What type of channels are the signaling machinery proteins localized near in cardiac muscle T-tubules?
What type of channels are the signaling machinery proteins localized near in cardiac muscle T-tubules?
Which receptor is associated with Oxytocin?
Which receptor is associated with Oxytocin?
Which receptor is involved in signaling via Gs and Gz?
Which receptor is involved in signaling via Gs and Gz?
Which receptor can activate Gq/11 and G12/13 signaling pathways?
Which receptor can activate Gq/11 and G12/13 signaling pathways?
Which receptor is associated with the vasopressin V1a?
Which receptor is associated with the vasopressin V1a?
Which receptors are involved in endogenous/heterologous signaling?
Which receptors are involved in endogenous/heterologous signaling?
Which receptors are associated with Gi, Gs, and Gq/11 signaling pathways?
Which receptors are associated with Gi, Gs, and Gq/11 signaling pathways?
Which receptors are involved in GTPγS o second messenger analysis?
Which receptors are involved in GTPγS o second messenger analysis?
If a receptor can activate many signaling pathways, how is one specific signaling pathway selected?
If a receptor can activate many signaling pathways, how is one specific signaling pathway selected?
What is the main difference between the internalization of Class A and Class B receptors with β-arrestin?
What is the main difference between the internalization of Class A and Class B receptors with β-arrestin?
Which process does β-arrestin briefly perform in relation to the β1-adrenergic receptor (β1-AR)?
Which process does β-arrestin briefly perform in relation to the β1-adrenergic receptor (β1-AR)?
What is the role of G proteins in internalization-dependent activation mediated by Class A/B receptors?
What is the role of G proteins in internalization-dependent activation mediated by Class A/B receptors?
What happens after the binding of β-arrestin in the context of Class A receptors?
What happens after the binding of β-arrestin in the context of Class A receptors?
How is internalization-dependent ERK signaling different between Class A receptors and Class B receptors?
How is internalization-dependent ERK signaling different between Class A receptors and Class B receptors?
What is the main effect of G protein mediated internalization-dependent activation after internalization?
What is the main effect of G protein mediated internalization-dependent activation after internalization?
Flashcards are hidden until you start studying
