Endocrine System | Thyroid Gland Quiz
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Questions and Answers

What is the approximate daily secretion of T3 by the human thyroid gland?

  • 2 μg
  • 80 μg
  • 7 nmol
  • 4 μg (correct)

Which of the following is true about free thyroid hormones in plasma?

  • They are in equilibrium with protein-bound thyroid hormones (correct)
  • They do not inhibit pituitary secretion of TSH
  • They are not physiologically active
  • They are not added to the circulating pool by the thyroid

What is the normal total plasma T4 level in adults approximately?

  • 7 nmol/L
  • 0.15 μg/dL
  • 80 μg/dL
  • 8 μg/dL (correct)

Which thyroid hormone is relatively lipophilic and has free forms in plasma that are physiologically active?

<p>T3 (A)</p> Signup and view all the answers

How do free thyroid hormones contribute to the regulation of TSH secretion?

<p>By inhibiting pituitary secretion of TSH (B)</p> Signup and view all the answers

What is the main function of the thyroid gland?

<p>Secreting calcitonin to regulate calcium levels (D)</p> Signup and view all the answers

How is thyroglobulin secreted into the colloid in the thyroid gland?

<p>By exocytosis of granules (D)</p> Signup and view all the answers

What enzyme mediates the oxidation and reaction of iodide with thyroglobulin?

<p>Thyroid peroxidase (D)</p> Signup and view all the answers

What happens to the thyroid hormones produced by the thyroid gland until they are needed?

<p>They remain part of the thyroglobulin molecule in the colloid (C)</p> Signup and view all the answers

What is the first product formed in the thyroid hormone synthesis process?

<p>Monoiodotyrosine (MIT) (D)</p> Signup and view all the answers

How is T3 formed in the thyroid hormone synthesis process?

<p>Condensation of MIT with DIT (A)</p> Signup and view all the answers

Which component serves as a reservoir of thyroid hormones in the thyroid gland?

<p>Colloid (D)</p> Signup and view all the answers

What could happen if a person ingests a diet completely devoid of iodide for a long time?

<p>Decline in circulating thyroid hormone levels (C)</p> Signup and view all the answers

Which enzyme generates reactive iodine species for attacking thyroglobulin in the thyroid hormone synthesis process?

<p>Thyroid peroxidase (A)</p> Signup and view all the answers

What compound is formed by the condensation of DIT with MIT in the thyroid hormone synthesis process?

<p>Reverse T3 (RT3) (C)</p> Signup and view all the answers

What is the average distribution of T4 in the normal human thyroid from iodinated compounds?

<p>35% (A)</p> Signup and view all the answers

Which theory explains the coupling reaction where both DIT molecules are attached to thyroglobulin?

<p>Intramolecular coupling theory (B)</p> Signup and view all the answers

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