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Endocrine System | Thyroid Gland Quiz

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Questions and Answers

What is the approximate daily secretion of T3 by the human thyroid gland?

2 μg

80 μg

7 nmol

4 μg (correct)

Which of the following is true about free thyroid hormones in plasma?

They are in equilibrium with protein-bound thyroid hormones (correct)

They do not inhibit pituitary secretion of TSH

They are not physiologically active

They are not added to the circulating pool by the thyroid

What is the normal total plasma T4 level in adults approximately?

7 nmol/L

0.15 μg/dL

80 μg/dL

8 μg/dL (correct)

Which thyroid hormone is relatively lipophilic and has free forms in plasma that are physiologically active?

T3 Signup and view all the answers

How do free thyroid hormones contribute to the regulation of TSH secretion?

By inhibiting pituitary secretion of TSH Signup and view all the answers

What is the main function of the thyroid gland?

Secreting calcitonin to regulate calcium levels Signup and view all the answers

How is thyroglobulin secreted into the colloid in the thyroid gland?

By exocytosis of granules Signup and view all the answers

What enzyme mediates the oxidation and reaction of iodide with thyroglobulin?

Thyroid peroxidase Signup and view all the answers

What happens to the thyroid hormones produced by the thyroid gland until they are needed?

They remain part of the thyroglobulin molecule in the colloid Signup and view all the answers

What is the first product formed in the thyroid hormone synthesis process?

Monoiodotyrosine (MIT) Signup and view all the answers

How is T3 formed in the thyroid hormone synthesis process?

Condensation of MIT with DIT Signup and view all the answers

Which component serves as a reservoir of thyroid hormones in the thyroid gland?

Colloid Signup and view all the answers

What could happen if a person ingests a diet completely devoid of iodide for a long time?

Decline in circulating thyroid hormone levels Signup and view all the answers

Which enzyme generates reactive iodine species for attacking thyroglobulin in the thyroid hormone synthesis process?

Thyroid peroxidase Signup and view all the answers

What compound is formed by the condensation of DIT with MIT in the thyroid hormone synthesis process?

Reverse T3 (RT3) Signup and view all the answers

What is the average distribution of T4 in the normal human thyroid from iodinated compounds?

35% Signup and view all the answers

Which theory explains the coupling reaction where both DIT molecules are attached to thyroglobulin?

Intramolecular coupling theory Signup and view all the answers