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Where are the parathyroid glands located?
Where are the parathyroid glands located?
What is the effect of parathyroid hormone on blood Ca2+ levels?
What is the effect of parathyroid hormone on blood Ca2+ levels?
What is one of the effects of parathyroid hormone on bone?
What is one of the effects of parathyroid hormone on bone?
What is another effect of parathyroid hormone?
What is another effect of parathyroid hormone?
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What is the effect of parathyroid hormone on urina excretion?
What is the effect of parathyroid hormone on urina excretion?
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What is the role of parathyroid hormone in the synthesis of calcitriol?
What is the role of parathyroid hormone in the synthesis of calcitriol?
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What is the function of thyroxine (T4) and triiodothyronine (T3)?
What is the function of thyroxine (T4) and triiodothyronine (T3)?
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What is the location of the parathyroid glands?
What is the location of the parathyroid glands?
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What is the function of calcitonin?
What is the function of calcitonin?
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What is the number of lobes in the thyroid gland?
What is the number of lobes in the thyroid gland?
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Which of the following is NOT a function of thyroid hormones?
Which of the following is NOT a function of thyroid hormones?
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What is the name of the vein that drains the thyroid gland?
What is the name of the vein that drains the thyroid gland?
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What is the function of the isthmus in the thyroid gland?
What is the function of the isthmus in the thyroid gland?
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Which of the following is a characteristic of the thyroid gland?
Which of the following is a characteristic of the thyroid gland?
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What is the location of the pineal gland in the brain?
What is the location of the pineal gland in the brain?
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What happens to the pineal gland after age 7?
What happens to the pineal gland after age 7?
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What is the function of the pineal gland in relation to circadian rhythms?
What is the function of the pineal gland in relation to circadian rhythms?
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What is the role of the thymus in the immune system?
What is the role of the thymus in the immune system?
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What is the location of the thymus in the body?
What is the location of the thymus in the body?
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What happens to the thymus after puberty?
What happens to the thymus after puberty?
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What is the function of the thymus in relation to hormone production?
What is the function of the thymus in relation to hormone production?
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What is unique about the thymus in terms of its role in the body?
What is unique about the thymus in terms of its role in the body?
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What is the location of the adrenal glands in the body?
What is the location of the adrenal glands in the body?
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What is the function of the zona glomerulosa in the adrenal cortex?
What is the function of the zona glomerulosa in the adrenal cortex?
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What is the function of the adrenal medulla?
What is the function of the adrenal medulla?
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What is the function of glucagon in the pancreatic islets?
What is the function of glucagon in the pancreatic islets?
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What is the function of somatostatin in the pancreatic islets?
What is the function of somatostatin in the pancreatic islets?
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What is the function of estradiol in the ovaries?
What is the function of estradiol in the ovaries?
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What is the function of the skin in the endocrine system?
What is the function of the skin in the endocrine system?
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What is the function of the liver in the endocrine system?
What is the function of the liver in the endocrine system?
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What is the function of the kidneys in the endocrine system?
What is the function of the kidneys in the endocrine system?
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What is the function of natriuretic peptides in the heart?
What is the function of natriuretic peptides in the heart?
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What is the name of the gland located below the larynx?
What is the name of the gland located below the larynx?
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What is the color of the thyroid gland?
What is the color of the thyroid gland?
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What is the relationship between the two diagrams shown?
What is the relationship between the two diagrams shown?
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What can be inferred about the thyroid gland from the diagrams?
What can be inferred about the thyroid gland from the diagrams?
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What is the significance of the isthmus in the thyroid gland?
What is the significance of the isthmus in the thyroid gland?
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What is the largest endocrine gland in the human body?
What is the largest endocrine gland in the human body?
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What is the location of the diaphragm in the human body?
What is the location of the diaphragm in the human body?
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What is the relationship between the thyroid gland and the trachea?
What is the relationship between the thyroid gland and the trachea?
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Study Notes
Endocrine System
- The endocrine system consists of glands that produce and secrete hormones that regulate various bodily functions.
Pineal Gland
- Located beneath the posterior end of the corpus callosum, attached to the roof of the third ventricle.
- Undergoes involution (shrinkage) after age 7, decreasing by 75% by the end of puberty.
- Synthesizes melatonin from serotonin during the night, which synchronizes physiological functions with 24-hour circadian rhythms.
- Fluctuates seasonally with changes in daylight.
Thymus
- Located in the mediastinum, superior to the heart.
- Plays a role in the endocrine, lymphatic, and immune systems.
- Goes through involution after puberty.
- Site of maturation of T cells, which are important in immune defense.
- Secrete hormones (thymopoietin, thymosin, and thymulin) that stimulate the development of other lymphatic organs and activity.
Thyroid Gland
- Largest endocrine gland, composed of two lobes and an isthmus below the larynx.
- Dark reddish-brown color due to the presence of iodine atoms.
- Secrete hormones thyroxine (T4) and triiodothyronine (T3), which:
- Increase metabolic rate, oxygen consumption, heat production, appetite, and growth hormone secretion.
- Stimulate osteoblast activity and bone formation.
- Parafollicular (C) cells secrete calcitonin, which:
- Stimulates osteoblast activity and bone formation.
- Decreases blood calcium levels.
Parathyroid Glands
- Usually four glands partially embedded in the posterior surface of the thyroid gland.
- Secrete parathyroid hormone (PTH), which:
- Increases blood calcium levels.
- Promotes synthesis of calcitriol.
- Increases absorption of calcium.
- Increases bone resorption.
Adrenal Glands
- Small glands located on top of each kidney.
- Retroperitoneal, like the kidney.
- Adrenal cortex and medulla formed by the merger of two fetal glands with different origins and functions.
- Adrenal medulla:
- Acts as an endocrine gland and sympathetic ganglion of the sympathetic nervous system.
- Innervated by sympathetic fibers.
- When stimulated, releases catecholamines (epinephrine and norepinephrine) and a trace of dopamine directly into the bloodstream.
- Increases alertness, prepares body for physical activity, and increases blood pressure, heart rate, blood flow to muscles, and metabolic rate.
- Adrenal cortex:
- Produces more than 25 steroid hormones called corticosteroids or corticoids.
- Secrete five major steroid hormones from three layers of glandular tissue:
- Zona glomerulosa (thin, outer layer): secretes mineralocorticoid (aldosterone) that regulates the body's electrolyte balance.
- Zona fasciculata (thick, middle layer): secretes glucocorticoids, especially cortisol, which stimulates fat and protein catabolism, gluconeogenesis, and has anti-inflammatory effects.
- Zona reticularis (narrow, inner layer): secretes sex steroids, androgens, and estrogens.
Pancreatic Islets
- Exocrine digestive gland and endocrine cell clusters (pancreatic islets) found retroperitoneal, inferior, and posterior to the stomach.
- Pancreatic islets:
- Beta cells: secrete insulin, which lowers blood glucose levels.
- Alpha cells: secrete glucagon, which increases blood glucose levels.
- Delta cells: secrete somatostatin, which partially suppresses secretion of glucagon and insulin.
- G cells: secrete gastrin, which stimulates stomach acid secretion, motility, and emptying.
Gonads
- Ovarian hormones:
- Estradiol, progesterone, and inhibin.
- Functions: development of female reproductive system and physique, regulate menstrual cycle, sustain pregnancy, and prepare mamma glands for lactation.
- Testicular hormones:
- Testosterone, androgens, estrogen, and inhibin.
- Functions: development of male reproductive system, sustain sperm production, and regulate sex drive.
Endocrine Functions of Other Tissues and Organs
- Skin: keratinocytes convert a cholesterol-like steroid into cholecalciferol using UV from the sun.
- Liver: secretes calcidiol, angiotensinogen, and erythropoietin.
- Kidneys: convert calcidiol to calcitriol, the active form of vitamin D, and secrete renin and erythropoietin.
- Heart: cardiac muscle secretes natriuretic peptides, which decrease blood volume and blood pressure.
- Stomach and small intestine: secrete at least 10 enteric hormones that coordinate digestive motility and glandular secretion.
Endocrine Disorders
- No specific details mentioned in the text.
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Description
Learn about the pineal gland, its location, and its changes with age. This quiz is presented by Dr. Ali Al-najjar, a General Surgeon.