Endocrine System 101

• Growth hormone (GH) is produced by the anterior pituitary gland and promotes protein synthesis and tissue building.
• GH levels are controlled by the release of GHRH and GHIH from the hypothalamus.
• GH has a glucose-sparing effect, stimulates the uptake of amino acids, and initiates the diabetogenic effect.
• GH indirectly mediates growth and protein synthesis by triggering the production of insulin-like growth factors (IGFs).
• Dysfunction of the endocrine system's control of growth can result in disorders such as gigantism, acromegaly, and pituitary dwarfism.
• Thyroid-stimulating hormone (TSH) regulates the activity of the thyroid gland and is released from the anterior pituitary in response to thyrotropin-releasing hormone (TRH) from the hypothalamus.
• Elevated levels of thyroid hormones trigger a drop in production of TRH and TSH in a negative feedback loop.
• Adrenocorticotropic hormone (ACTH) stimulates the adrenal cortex to secrete corticosteroid hormones such as cortisol.
• ACTH is regulated by the corticotropin-releasing hormone (CRH) from the hypothalamus in response to normal physiologic rhythms.
• POMC produces several biologically active molecules when cleaved, including ACTH, melanocyte-stimulating hormone, and endorphins.

Test your knowledge of the endocrine system with this quiz focused on growth hormone, thyroid-stimulating hormone, and adrenocorticotropic hormone. Learn about the functions, regulation, and dysfunctions of these hormones and their impact on the body. From gigantism to cortisol secretion, this quiz covers it all. Challenge yourself and see how much you know about these important hormones and their role in maintaining homeostasis.