10 Questions
Which of the following is NOT a physiological action of parathyroid hormone (PTH)?
Inhibition of osteoclast activity in bone
What is the primary site of synthesis for calcitriol?
Kidneys
Which hormone plays a role in promoting bone resorption and increasing plasma calcium levels?
Cortisol
What are the symptoms of hypercalcaemia?
Confusion and fatigue
In which body system does calcium play a key role in regulating hormonal secretion?
Endocrine system
What percentage of filtered calcium is typically reabsorbed in the kidneys?
97-99%
Which cell type is responsible for secreting bone matrix on which calcium and phosphate precipitate?
Osteoblasts
What is the normal range of ionized calcium in the plasma?
2.2-2.6 mmol/L
What factors are responsible for maintaining serum calcium levels within narrow limits?
Parathyroid hormone and calcitriol
During which phase of life does the rate of bone formation exceed resorption, leading to an increase in skeletal mass?
Adolescence
Study Notes
Parathyroid Hormone (PTH)
- Not a physiological action of PTH: (answer needs to be provided)
Calcitriol Synthesis
- Primary site of synthesis for calcitriol: (answer needs to be provided)
Hormone Regulation
- Hormone that promotes bone resorption and increases plasma calcium levels: PTH
- Hormone that plays a role in regulating hormonal secretion in the endocrine system: calcium
Hypercalcaemia
- Symptoms of hypercalcaemia: (answer needs to be provided)
Calcium Regulation
- Percentage of filtered calcium reabsorbed in the kidneys: (answer needs to be provided)
- Factors responsible for maintaining serum calcium levels within narrow limits: PTH, vitamin D, and calcitonin
Bone Formation
- Cell type responsible for secreting bone matrix on which calcium and phosphate precipitate: osteoblasts
Calcium Levels
- Normal range of ionized calcium in the plasma: (answer needs to be provided)
Bone Development
- Phase of life where the rate of bone formation exceeds resorption, leading to an increase in skeletal mass: growth and development (e.g. childhood, adolescence)
Test your understanding of the endocrine control of calcium homeostasis in physiology. This quiz covers the body's calcium pools, synthesis and actions of parathyroid hormone, calcitriol, and calcitonin, as well as the control of their synthesis and the endocrine regulation of bone metabolism.
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