Endocrine Control of Calcium Homeostasis in Physiology

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Questions and Answers

Which of the following is NOT a physiological action of parathyroid hormone (PTH)?

  • Stimulation of phosphate reabsorption in the kidneys
  • Promotion of calcium reabsorption in the kidneys
  • Inhibition of osteoclast activity in bone (correct)
  • Enhancement of calcitriol synthesis in the kidneys

What is the primary site of synthesis for calcitriol?

  • Pancreas
  • Liver
  • Kidneys (correct)
  • Parathyroid gland

Which hormone plays a role in promoting bone resorption and increasing plasma calcium levels?

  • Calcitonin
  • Thyroid hormone
  • Cortisol (correct)
  • Insulin

What are the symptoms of hypercalcaemia?

<p>Confusion and fatigue (C)</p> Signup and view all the answers

In which body system does calcium play a key role in regulating hormonal secretion?

<p>Endocrine system (A)</p> Signup and view all the answers

What percentage of filtered calcium is typically reabsorbed in the kidneys?

<p>97-99% (D)</p> Signup and view all the answers

Which cell type is responsible for secreting bone matrix on which calcium and phosphate precipitate?

<p>Osteoblasts (B)</p> Signup and view all the answers

What is the normal range of ionized calcium in the plasma?

<p>2.2-2.6 mmol/L (A)</p> Signup and view all the answers

What factors are responsible for maintaining serum calcium levels within narrow limits?

<p>Parathyroid hormone and calcitriol (B)</p> Signup and view all the answers

During which phase of life does the rate of bone formation exceed resorption, leading to an increase in skeletal mass?

<p>Adolescence (D)</p> Signup and view all the answers

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Study Notes

Parathyroid Hormone (PTH)

  • Not a physiological action of PTH: (answer needs to be provided)

Calcitriol Synthesis

  • Primary site of synthesis for calcitriol: (answer needs to be provided)

Hormone Regulation

  • Hormone that promotes bone resorption and increases plasma calcium levels: PTH
  • Hormone that plays a role in regulating hormonal secretion in the endocrine system: calcium

Hypercalcaemia

  • Symptoms of hypercalcaemia: (answer needs to be provided)

Calcium Regulation

  • Percentage of filtered calcium reabsorbed in the kidneys: (answer needs to be provided)
  • Factors responsible for maintaining serum calcium levels within narrow limits: PTH, vitamin D, and calcitonin

Bone Formation

  • Cell type responsible for secreting bone matrix on which calcium and phosphate precipitate: osteoblasts

Calcium Levels

  • Normal range of ionized calcium in the plasma: (answer needs to be provided)

Bone Development

  • Phase of life where the rate of bone formation exceeds resorption, leading to an increase in skeletal mass: growth and development (e.g. childhood, adolescence)

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