Embryonic Development Overview

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59 Questions

Which organ system is NOT derived from endoderm?

Thymus

How does smoking during pregnancy primarily affect fetal development?

Brain hypoplasia

In gestational exposure to cocaine, what is a common impact on the fetus?

Cardiac malformation

What effect does alcohol consumption during pregnancy have on fetal development?

Microcephaly

Which medication used for birth control can have teratogenic effects on the developing fetus?

Combined oral contraceptives

How does exposure to environmental toxins impact fetal morphogenesis?

Eye malformation

During which period is the fetus most vulnerable to the effects of teratogens?

Embryonic period (first 8 weeks after fertilization)

Which layer of the embryonic disc gives rise to the pituitary gland?

Ectoderm

What is the source of adrenal cortex hormones such as aldosterone and cortisol?

Mesoderm

Which substance can have adverse effects on fetal development if consumed during pregnancy?

Cocaine in any amount

What impact can smoking have on fetal development?

Increases the risk of preterm delivery and low birth weight

What is an effect of excessive vitamin A intake during the first trimester of pregnancy?

Microcephaly

Which layer of the embryo gives rise to the epinephrine and norepinephrine producing cells of the adrenal gland?

Neural crest

Which birth control medication is contraindicated during pregnancy due to its teratogenic effects?

Propecia

What is a potential consequence of alcohol consumption during the first trimester of pregnancy?

Congenital heart defects

How does cocaine use during pregnancy primarily affect the fetus?

Placental abruption

Which adverse effect is associated with smoking during pregnancy?

Placental anomalies

What is a risk of exposure to methylmercury found in fish and seafood during pregnancy?

Delayed milestones

Which embryonic gene is primarily responsible for CNS development and limb patterning?

Sonic Hedgehog (SHH)

What is the consequence of a mutation in the Sonic Hedgehog (SHH) gene during embryonic development?

Single-lobed brain and facial abnormalities

Which gene is crucial for limb proximal-distal outgrowth and is produced at the limb bud?

Fibroblast Growth Factor (FGF)

What is the role of Homeobox genes (HOX) in embryonic development?

Regulation of anterior-posterior axis patterning

Which gene family is associated with limb malformations such as polydactyly and syndactyly when mutated?

Homeobox genes (HOX)

How does a mutation in the Sonic Hedgehog (SHH) gene affect CNS development?

Development of forebrain through abnormal division

During which stage of early embryonic development does the formation of the blastula from morula occur?

Two-Cell stage

What is the function of the primitive streak in the embryonic development process?

Initiates the process of gastrulation

In human embryonic development, what gives rise to all the tissues of the body?

Inner cell mass

Which cell layer gives rise to the three germ layers during gastrulation?

Epiblast

What marks the start of gastrulation during early embryonic development?

Presence of the primitive streak

Which stage is characterized by the reorganization of the blastula into a two-three-layered embryo known as the gastrula?

Gastrulation

What is the embryonic structure key for the development of the head and neck?

Pharyngeal arches

Which embryonic structure gives rise to ectoderm?

Pharyngeal clefts

Which component of the pharyngeal apparatus is derived from endoderm?

Pharyngeal pouches

Which embryonic structure is associated with DiGeorge Syndrome?

Pharyngeal arches

Which structure is NOT a component of the pharyngeal apparatus?

Branchial cleft cysts

The ultimobranchial body contributes to the development of which structures?

Thyroid gland

Which component is primarily affected in individuals with abnormalities related to pharyngeal clefts?

Muscular element

What is the classic triad associated with DiGeorge Syndrome?

Loss of T-cells, recurrent infections, congenital heart defects

Which structure is most commonly affected in patients with DiGeorge Syndrome?

Pharyngeal pouches

Where is a branchial cleft cyst most commonly located?

Above the angle of the mandible

Which structure is NOT a derivative of the pharyngeal pouches?

External auditory meatus

Which structure shares a similar embryological origin with the ultimobranchial body?

Thyroid gland

What distinguishes a branchial cleft cyst from a thyroglossal duct cyst?

Location within the neck

Which embryonic structures are lined by ectoderm?

Branchial clefts

Which structures fail to fuse in the formation of the primary palate?

Intermaxillary segment with maxillary process

Which condition results from the failure of fusion of two lateral palatine shelves or the lateral palatine shelf with the nasal septum in palate formation?

Pharyngeal cleft

What structures form the primary palate in embryonic development?

Medial nasal processes

Which defect occurs between the 4th and 7th weeks of pregnancy involving openings in a baby's upper lip?

Cleft lip

What condition arises from a failure of fusion of the intermaxillary segment with the maxillary process?

Cleft lip

Which structure fails to fuse in cleft palate formation?

Lateral palatine shelves with each other

Which condition involves openings in a baby's roof of the mouth (palate) and occurs between the 6th and 9th weeks of pregnancy?

Cleft palate

What defect results from a failure of fusion of two lateral palatine shelves or failure with other structures in palate formation?

Cleft palate

Which embryonic structure gives rise to the ultimobranchial body in the developing thyroid?

Fourth pharyngeal pouch

In human embryology, which condition is closely related to defects in the development of the third and fourth pharyngeal pouches?

DiGeorge Syndrome

Which of the following structures is derived from the first pharyngeal cleft during embryonic development?

Eustachian tube

A patient presents with a lateral neck mass that represents a remnant of the branchial apparatus. Which branchial cleft is most likely involved in this condition?

Second branchial cleft

Which anatomical structure is most likely affected in a patient with a defect in the development of the fourth pharyngeal pouch?

Ventral parathyroid glands

Which of the following represents a condition characterized by defects in the formation of pharyngeal pouches and neural crest cells migration?

Treacher Collins Syndrome

Which embryonic structure gives rise to the ultimobranchial body that later incorporates into the thyroid gland?

Fourth pharyngeal pouch

Explore the stages of embryonic development within the first 8 weeks after fertilization, from organogenesis to the establishment of adult structures. Learn about the development of the heart, limbs, and key layers like ectoderm, mesoderm, and endoderm.

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