Embryonic Development Overview
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Questions and Answers

Which organ system is NOT derived from endoderm?

  • Thymus (correct)
  • Digestive tract
  • Liver
  • Respiratory system

How does smoking during pregnancy primarily affect fetal development?

  • Renal agenesis
  • Brain hypoplasia (correct)
  • Growth failure of limbs
  • Lung malformation

In gestational exposure to cocaine, what is a common impact on the fetus?

  • Respiratory system abnormalities
  • Liver aplasia
  • Cardiac malformation (correct)
  • Thyroid hypoplasia

What effect does alcohol consumption during pregnancy have on fetal development?

<p>Microcephaly (B)</p> Signup and view all the answers

Which medication used for birth control can have teratogenic effects on the developing fetus?

<p>Combined oral contraceptives (C)</p> Signup and view all the answers

How does exposure to environmental toxins impact fetal morphogenesis?

<p>Eye malformation (A)</p> Signup and view all the answers

During which period is the fetus most vulnerable to the effects of teratogens?

<p>Embryonic period (first 8 weeks after fertilization) (C)</p> Signup and view all the answers

Which layer of the embryonic disc gives rise to the pituitary gland?

<p>Ectoderm (A)</p> Signup and view all the answers

What is the source of adrenal cortex hormones such as aldosterone and cortisol?

<p>Mesoderm (C)</p> Signup and view all the answers

Which substance can have adverse effects on fetal development if consumed during pregnancy?

<p>Cocaine in any amount (A)</p> Signup and view all the answers

What impact can smoking have on fetal development?

<p>Increases the risk of preterm delivery and low birth weight (A)</p> Signup and view all the answers

What is an effect of excessive vitamin A intake during the first trimester of pregnancy?

<p>Microcephaly (B)</p> Signup and view all the answers

Which layer of the embryo gives rise to the epinephrine and norepinephrine producing cells of the adrenal gland?

<p>Neural crest (A)</p> Signup and view all the answers

Which birth control medication is contraindicated during pregnancy due to its teratogenic effects?

<p>Propecia (A)</p> Signup and view all the answers

What is a potential consequence of alcohol consumption during the first trimester of pregnancy?

<p>Congenital heart defects (C)</p> Signup and view all the answers

How does cocaine use during pregnancy primarily affect the fetus?

<p>Placental abruption (D)</p> Signup and view all the answers

Which adverse effect is associated with smoking during pregnancy?

<p>Placental anomalies (C)</p> Signup and view all the answers

What is a risk of exposure to methylmercury found in fish and seafood during pregnancy?

<p>Delayed milestones (A)</p> Signup and view all the answers

Which embryonic gene is primarily responsible for CNS development and limb patterning?

<p>Sonic Hedgehog (SHH) (A)</p> Signup and view all the answers

What is the consequence of a mutation in the Sonic Hedgehog (SHH) gene during embryonic development?

<p>Single-lobed brain and facial abnormalities (D)</p> Signup and view all the answers

Which gene is crucial for limb proximal-distal outgrowth and is produced at the limb bud?

<p>Fibroblast Growth Factor (FGF) (D)</p> Signup and view all the answers

What is the role of Homeobox genes (HOX) in embryonic development?

<p>Regulation of anterior-posterior axis patterning (B)</p> Signup and view all the answers

Which gene family is associated with limb malformations such as polydactyly and syndactyly when mutated?

<p>Homeobox genes (HOX) (D)</p> Signup and view all the answers

How does a mutation in the Sonic Hedgehog (SHH) gene affect CNS development?

<p>Development of forebrain through abnormal division (C)</p> Signup and view all the answers

During which stage of early embryonic development does the formation of the blastula from morula occur?

<p>Two-Cell stage (B)</p> Signup and view all the answers

What is the function of the primitive streak in the embryonic development process?

<p>Initiates the process of gastrulation (C)</p> Signup and view all the answers

In human embryonic development, what gives rise to all the tissues of the body?

<p>Inner cell mass (A)</p> Signup and view all the answers

Which cell layer gives rise to the three germ layers during gastrulation?

<p>Epiblast (B)</p> Signup and view all the answers

What marks the start of gastrulation during early embryonic development?

<p>Presence of the primitive streak (A)</p> Signup and view all the answers

Which stage is characterized by the reorganization of the blastula into a two-three-layered embryo known as the gastrula?

<p>Gastrulation (A)</p> Signup and view all the answers

What is the embryonic structure key for the development of the head and neck?

<p>Pharyngeal arches (A)</p> Signup and view all the answers

Which embryonic structure gives rise to ectoderm?

<p>Pharyngeal clefts (A)</p> Signup and view all the answers

Which component of the pharyngeal apparatus is derived from endoderm?

<p>Pharyngeal pouches (D)</p> Signup and view all the answers

Which embryonic structure is associated with DiGeorge Syndrome?

<p>Pharyngeal arches (A)</p> Signup and view all the answers

Which structure is NOT a component of the pharyngeal apparatus?

<p>Branchial cleft cysts (C)</p> Signup and view all the answers

The ultimobranchial body contributes to the development of which structures?

<p>Thyroid gland (C)</p> Signup and view all the answers

Which component is primarily affected in individuals with abnormalities related to pharyngeal clefts?

<p>Muscular element (B)</p> Signup and view all the answers

What is the classic triad associated with DiGeorge Syndrome?

<p>Loss of T-cells, recurrent infections, congenital heart defects (D)</p> Signup and view all the answers

Which structure is most commonly affected in patients with DiGeorge Syndrome?

<p>Pharyngeal pouches (A)</p> Signup and view all the answers

Where is a branchial cleft cyst most commonly located?

<p>Above the angle of the mandible (A)</p> Signup and view all the answers

Which structure is NOT a derivative of the pharyngeal pouches?

<p>External auditory meatus (B)</p> Signup and view all the answers

Which structure shares a similar embryological origin with the ultimobranchial body?

<p>Thyroid gland (A)</p> Signup and view all the answers

What distinguishes a branchial cleft cyst from a thyroglossal duct cyst?

<p>Location within the neck (A)</p> Signup and view all the answers

Which embryonic structures are lined by ectoderm?

<p><em>Branchial clefts</em> (C)</p> Signup and view all the answers

Which structures fail to fuse in the formation of the primary palate?

<p>Intermaxillary segment with maxillary process (D)</p> Signup and view all the answers

Which condition results from the failure of fusion of two lateral palatine shelves or the lateral palatine shelf with the nasal septum in palate formation?

<p>Pharyngeal cleft (D)</p> Signup and view all the answers

What structures form the primary palate in embryonic development?

<p>Medial nasal processes (A)</p> Signup and view all the answers

Which defect occurs between the 4th and 7th weeks of pregnancy involving openings in a baby's upper lip?

<p>Cleft lip (D)</p> Signup and view all the answers

What condition arises from a failure of fusion of the intermaxillary segment with the maxillary process?

<p>Cleft lip (A)</p> Signup and view all the answers

Which structure fails to fuse in cleft palate formation?

<p>Lateral palatine shelves with each other (D)</p> Signup and view all the answers

Which condition involves openings in a baby's roof of the mouth (palate) and occurs between the 6th and 9th weeks of pregnancy?

<p>Cleft palate (B)</p> Signup and view all the answers

What defect results from a failure of fusion of two lateral palatine shelves or failure with other structures in palate formation?

<p>Cleft palate (A)</p> Signup and view all the answers

Which embryonic structure gives rise to the ultimobranchial body in the developing thyroid?

<p>Fourth pharyngeal pouch (D)</p> Signup and view all the answers

In human embryology, which condition is closely related to defects in the development of the third and fourth pharyngeal pouches?

<p>DiGeorge Syndrome (D)</p> Signup and view all the answers

Which of the following structures is derived from the first pharyngeal cleft during embryonic development?

<p>Eustachian tube (A)</p> Signup and view all the answers

A patient presents with a lateral neck mass that represents a remnant of the branchial apparatus. Which branchial cleft is most likely involved in this condition?

<p>Second branchial cleft (D)</p> Signup and view all the answers

Which anatomical structure is most likely affected in a patient with a defect in the development of the fourth pharyngeal pouch?

<p>Ventral parathyroid glands (B)</p> Signup and view all the answers

Which of the following represents a condition characterized by defects in the formation of pharyngeal pouches and neural crest cells migration?

<p>Treacher Collins Syndrome (B)</p> Signup and view all the answers

Which embryonic structure gives rise to the ultimobranchial body that later incorporates into the thyroid gland?

<p>Fourth pharyngeal pouch (C)</p> Signup and view all the answers

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