Embryonic Development and Prenatal Testing
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Questions and Answers

Which of the following structures forms from the epiblast during the second week of development?

  • Trophoblast
  • Hypoblast
  • Yolk sac
  • Amniotic cavity (correct)
  • Which of the following is derived from the ectoderm?

  • Skin and nervous system (correct)
  • Liver and pancreas
  • Heart and blood vessels
  • Muscles and bones
  • The process of neurulation results in the formation of which structure?

  • Somites
  • Notochord
  • Neural tube (correct)
  • Pharyngeal arches
  • The neural tube closes by the end of which week of development?

    <p>Week 4</p> Signup and view all the answers

    The placental barrier consists of which of the following layers?

    <p>Cytotrophoblast, syncytiotrophoblast, and fetal capillary endothelium</p> Signup and view all the answers

    The umbilical cord is composed of:

    <p>Two arteries and one vein</p> Signup and view all the answers

    Which of the following teratogens is known to cause limb defects if a pregnant woman is exposed during the critical period?

    <p>Thalidomide</p> Signup and view all the answers

    A child born with a cleft palate is most likely to have been exposed to which teratogen during the first trimester?

    <p>Retinoic acid</p> Signup and view all the answers

    Which of the following prenatal tests is most commonly used to assess the structure of the fetus at various stages of pregnancy?

    <p>Ultrasound</p> Signup and view all the answers

    Chorionic villus sampling is typically performed during which week of pregnancy?

    <p>Week 12-14</p> Signup and view all the answers

    A 28-year-old pregnant woman comes for her first prenatal check-up at 16 weeks of gestation. She has a family history of sickle cell disease and requests genetic testing. What is the most appropriate prenatal diagnostic test for her?

    <p>Carrier screening for sickle cell disease</p> Signup and view all the answers

    A 24-year-old woman in her first trimester presents to the emergency room with severe abdominal pain and light vaginal bleeding. Ultrasound confirms a miscarriage. The patient is concerned about future pregnancies. What is the most appropriate next step to assess her reproductive health?

    <p>Serum progesterone levels</p> Signup and view all the answers

    The embryonic period ends at the:

    <p>8th week</p> Signup and view all the answers

    The term "gestational age" refers to:

    <p>The age of the fetus from the first day of the last menstrual period</p> Signup and view all the answers

    The Sertoli cells in the male reproductive system are primarily responsible for:

    <p>Supporting and nourishing sperm cells</p> Signup and view all the answers

    In which phase of meiosis does genetic recombination occur?

    <p>Prophase I</p> Signup and view all the answers

    Which of the following best describes the difference between meiosis I and meiosis II?

    <p>Meiosis I results in the formation of two daughter cells, while meiosis II results in four daughter cells.</p> Signup and view all the answers

    Which of the following best describes spermatogenesis?

    <p>The process where one diploid germ cell produces four functional sperm.</p> Signup and view all the answers

    In females, the first meiotic division of oogenesis results in:

    <p>One secondary oocyte and one polar body</p> Signup and view all the answers

    Fertilization normally occurs in which part of the female reproductive system?

    <p>Fallopian tube</p> Signup and view all the answers

    The zona pellucida is important in fertilization because it:

    <p>Prevents polyspermy by blocking the entry of additional sperm.</p> Signup and view all the answers

    The inner cell mass of the blastocyst differentiates into:

    <p>The epiblast and hypoblast</p> Signup and view all the answers

    The cytotrophoblast and syncytiotrophoblast are derived from:

    <p>Trophoblast</p> Signup and view all the answers

    The notochord is derived from which germ layer?

    <p>Mesoderm</p> Signup and view all the answers

    The process of somite formation occurs during which phase of embryonic development?

    <p>Late gastrulation</p> Signup and view all the answers

    By the end of which week do the basic body plan and organ systems begin to form?

    <p>Week 4</p> Signup and view all the answers

    The heart starts to beat by which day of embryonic development?

    <p>Day 22</p> Signup and view all the answers

    The development of fetal limbs occurs during which month of pregnancy?

    <p>2nd month</p> Signup and view all the answers

    By the end of the 3rd trimester, the fetus has reached what approximate length?

    <p>50 cm</p> Signup and view all the answers

    Which of the following is responsible for nutrient and waste exchange between the mother and fetus?

    <p>Placenta</p> Signup and view all the answers

    The amniotic fluid serves all of the following functions except:

    <p>Providing nutrients to the fetus</p> Signup and view all the answers

    Which of the following genetic conditions is most likely associated with maternal age over 35 years?

    <p>Down syndrome</p> Signup and view all the answers

    Teratogenic effects of alcohol during pregnancy may result in which of the following?

    <p>Fetal alcohol syndrome</p> Signup and view all the answers

    The most common indication for amniocentesis is to:

    <p>Detect genetic disorders</p> Signup and view all the answers

    Non-invasive prenatal testing (NIPT) can detect which of the following conditions?

    <p>Chromosomal abnormalities, including Down syndrome</p> Signup and view all the answers

    A 30-year-old pregnant woman at 20 weeks gestation presents for routine prenatal care. Her ultrasound shows a low-lying placenta. What is the likely outcome for this pregnancy?

    <p>Placenta will likely move up as pregnancy progresses</p> Signup and view all the answers

    A woman with a history of multiple miscarriages is found to have a bicornuate uterus. What is the most appropriate management for her pregnancy?

    <p>Close monitoring for preterm labor</p> Signup and view all the answers

    Study Notes

    Embryonic Development and Prenatal Testing

    • Second Week Development: The amniotic cavity forms from the epiblast.
    • Ectoderm Derivatives: Skin and nervous system originate from the ectoderm.
    • Neurulation Outcome: Neurulation forms the neural tube.
    • Neural Tube Closure: The neural tube closes by the end of week 3.
    • Placental Barrier Layers: The placental barrier consists of cytotrophoblast, syncytiotrophoblast, and fetal capillary endothelium.
    • Umbilical Cord Composition: The umbilical cord is composed of two arteries and one vein.
    • Teratogens and Limb Defects: Thalidomide can cause limb defects if a pregnant woman is exposed during the critical period.
    • Cleft Palate Teratogen: Retinoic acid is a likely teratogen associated with cleft palate.
    • Prenatal Structure Assessment: Ultrasound is a common prenatal test used to assess fetal structure.
    • Chorionic Villus Sampling Timing: Chorionic villus sampling is typically done between weeks 12 and 14 of pregnancy.
    • Sickle Cell Carrier Screening: Carrier screening for sickle cell disease is an appropriate prenatal test for a woman with a family history.
    • Reproductive Health Assessment: Serum progesterone levels are important to assess reproductive health after a miscarriage.
    • Embryonic Period Length: The embryonic period ends at the 8th week.
    • Gestational Age Definition: Gestational age is the age of the fetus from the first day of the last menstrual period.
    • Sertoli Cell Function: Sertoli cells support and nourish sperm cells.
    • Meiosis Genetic Recombination: Genetic recombination occurs during Prophase I of meiosis.
    • Meiosis I vs. Meiosis II: Meiosis I separates homologous chromosomes, while meiosis II separates sister chromatids.
    • Spermatogenesis Process: Spermatogenesis produces four functional sperm from a single diploid germ cell.
    • Oogenesis in Females: Oogenesis in females results in one secondary oocyte and one polar body.
    • Fertilization Location: Fertilization typically occurs in the fallopian tube.
    • Zona Pellucida Function: The zona pellucida prevents polyspermy by blocking the entry of additional sperm.
    • Blastocyst Inner Cell Mass Differentiation: The inner cell mass of the blastocyst differentiates into the epiblast and hypoblast.
    • Cytotrophoblast and Syncytiotrophoblast Origin: Cytotrophoblast and syncytiotrophoblast originate from the trophoblast.
    • Notochord Germ Layer: The notochord is derived from the mesoderm.
    • Somite Formation Phase: Somite formation occurs during late gastrulation.
    • Body Plan and Organ System Formation Timing: The basic body plan and organ systems form by the end of week 4.
    • First Heartbeat Timing: The heart starts its first heartbeat around day 22.
    • Fetal Limb Development Month: Fetal limb development occurs during the second or 2nd month of pregnancy.
    • Third Trimester Fetus Length: At the end of the third trimester, the fetus is approximately 50 cm long.
    • Placenta Function: The placenta is responsible for nutrient and waste exchange between the mother and fetus.
    • Amniotic Fluid Function(s): The fluid cushions the fetus, assists in developing the lungs, maintains a constant temperature.

    Maternal Age & Genetic Conditions

    • Maternal Age & Down Syndrome: Down syndrome is more likely in women over 35.
    • Teratogenic Effects of Alcohol: Alcohol during pregnancy can result in fetal alcohol syndrome.
    • Amniocentesis Indication: Amniocentesis is mainly used to screen for neural tube defects.
    • Prenatal Testing (Non-Invasive): Non-invasive prenatal testing (NIPT) can detect conditions like cystic fibrosis.

    Prenatal Conditions & Management

    • Low-Lying Placenta Outcome: A low-lying placenta usually proceeds without complications and the placenta moves up during the pregnancy.
    • Uterine Abnormalities: Surgical correction might be needed for severe uterine abnormalities.
    • Miscarriage Management: Close monitoring for preterm labor is appropriate for women with a history of miscarriage and a uterine abnormality.

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    Description

    This quiz covers key aspects of embryonic development and prenatal testing procedures. It includes topics such as the formation of the amniotic cavity, the role of ectoderm derivatives, and the impacts of teratogens on fetal health. Test your knowledge on these vital concepts to understand prenatal care better.

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