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Questions and Answers
What is the cause of a ureterocele?
What is the cause of a ureterocele?
Which of the following is NOT a derivative of the Wolffian duct system?
Which of the following is NOT a derivative of the Wolffian duct system?
What is a potential outcome of horseshoe kidney?
What is a potential outcome of horseshoe kidney?
What is the role of testosterone from Leydig cells in male development?
What is the role of testosterone from Leydig cells in male development?
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Which of the following is NOT a potential treatment option for horseshoe kidney?
Which of the following is NOT a potential treatment option for horseshoe kidney?
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What is the name of the structure that separates the cloaca into two compartments?
What is the name of the structure that separates the cloaca into two compartments?
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Which of the following structures is NOT derived from the mesonephric duct in males?
Which of the following structures is NOT derived from the mesonephric duct in males?
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What is a potential anomaly that can occur due to a persistence of the cloaca?
What is a potential anomaly that can occur due to a persistence of the cloaca?
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What is the remnant of the allantoic duct called in adults?
What is the remnant of the allantoic duct called in adults?
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What is a characteristic symptom of a urachal abnormality?
What is a characteristic symptom of a urachal abnormality?
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Which of these components is NOT associated with hypospadias?
Which of these components is NOT associated with hypospadias?
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What is the term for a cyst that develops in the urachus due to a failure of the urachus to obliterate completely?
What is the term for a cyst that develops in the urachus due to a failure of the urachus to obliterate completely?
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What is the name of the landmark structure important in the development of the female genital system?
What is the name of the landmark structure important in the development of the female genital system?
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What is the earliest nephric stage in humans?
What is the earliest nephric stage in humans?
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Which of these structures develops into the male reproductive system?
Which of these structures develops into the male reproductive system?
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What is the functional significance of the mesonephros?
What is the functional significance of the mesonephros?
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Which of the following is NOT a derivative of the mesonephric duct?
Which of the following is NOT a derivative of the mesonephric duct?
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What is the correct order of development of the nephric systems?
What is the correct order of development of the nephric systems?
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What is the significance of the cuplike outgrowths (Bowman's capsule) in the mesonephros?
What is the significance of the cuplike outgrowths (Bowman's capsule) in the mesonephros?
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What is the primary function of Leydig cells?
What is the primary function of Leydig cells?
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What is a potential consequence of hypospadias?
What is a potential consequence of hypospadias?
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Which of these conditions IS NOT an anomaly of position in the nephric system?
Which of these conditions IS NOT an anomaly of position in the nephric system?
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Which of the following describes the role of the gubernaculum in testicular descent?
Which of the following describes the role of the gubernaculum in testicular descent?
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What is the key difference between International Reflux Classification and Spectrum of Chronic VUR?
What is the key difference between International Reflux Classification and Spectrum of Chronic VUR?
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Which of these is NOT a factor that can contribute to undescended testes?
Which of these is NOT a factor that can contribute to undescended testes?
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What is the most common treatment goal for hypospadias?
What is the most common treatment goal for hypospadias?
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What is a common symptom of cryptorchidism (undescended testes)?
What is a common symptom of cryptorchidism (undescended testes)?
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Which of these is NOT a potential complication of undescended testes?
Which of these is NOT a potential complication of undescended testes?
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Which of the following is a characteristic of epispadias?
Which of the following is a characteristic of epispadias?
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What is the gold standard diagnostic tool for Posterior Urethral Valves (PUV)?
What is the gold standard diagnostic tool for Posterior Urethral Valves (PUV)?
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Which of the following is NOT a clinical presentation of Posterior Urethral Valves (PUV)?
Which of the following is NOT a clinical presentation of Posterior Urethral Valves (PUV)?
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What is the primary objective of ablating Posterior Urethral Valves (PUV) with electric cautery?
What is the primary objective of ablating Posterior Urethral Valves (PUV) with electric cautery?
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Which of these conditions is classified as a functional cause of urinary incontinence?
Which of these conditions is classified as a functional cause of urinary incontinence?
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What is the most serious complication associated with untreated Posterior Urethral Valves (PUV)?
What is the most serious complication associated with untreated Posterior Urethral Valves (PUV)?
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In the context of the text, what does 'PARENCHYMAL SCARRING' refer to?
In the context of the text, what does 'PARENCHYMAL SCARRING' refer to?
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Which of these is associated with the embryological development of the vesicourethral unit?
Which of these is associated with the embryological development of the vesicourethral unit?
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What is the primary difference between a functional and an anatomical cause of urinary incontinence in the context of the provided notes?
What is the primary difference between a functional and an anatomical cause of urinary incontinence in the context of the provided notes?
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What is the most likely reason for 'Fetal growth retardation' in a fetus diagnosed with Posterior Urethral Valves (PUV)?
What is the most likely reason for 'Fetal growth retardation' in a fetus diagnosed with Posterior Urethral Valves (PUV)?
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Which of these is NOT a characteristic feature of Potter's Syndrome?
Which of these is NOT a characteristic feature of Potter's Syndrome?
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What is the most common cause of obstructive hydronephrosis in children?
What is the most common cause of obstructive hydronephrosis in children?
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What is the "Flap-Valve" effect of the Uterovesical Junction (UVJ) responsible for?
What is the "Flap-Valve" effect of the Uterovesical Junction (UVJ) responsible for?
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Which of the following is NOT a characteristic of the Uterovesical Junction (UVJ)?
Which of the following is NOT a characteristic of the Uterovesical Junction (UVJ)?
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What is the most common presentation of a child with Vesico-Ureteral Reflux (VUR)?
What is the most common presentation of a child with Vesico-Ureteral Reflux (VUR)?
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What is a possible clue that a child may have VUR, even without presenting with a UTI?
What is a possible clue that a child may have VUR, even without presenting with a UTI?
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What is the difference between primary and secondary Vesico-Ureteral Reflux (VUR)?
What is the difference between primary and secondary Vesico-Ureteral Reflux (VUR)?
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What is a possible treatment for a child with Vesico-Ureteral Reflux (VUR)?
What is a possible treatment for a child with Vesico-Ureteral Reflux (VUR)?
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Flashcards
Bifid Kidney
Bifid Kidney
A condition where the kidney is split into two distinct sections.
Wollfian Duct System
Wollfian Duct System
A set of male reproductive structures derived from mesonephric ducts.
Horseshoe Kidney
Horseshoe Kidney
A congenital anomaly where the kidneys are fused at the lower ends.
Ureterocele
Ureterocele
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Supernumerary Kidneys
Supernumerary Kidneys
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Cloaca
Cloaca
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Urogenital Sinus
Urogenital Sinus
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Persistent Cloaca
Persistent Cloaca
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Urachal Abnormalities
Urachal Abnormalities
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Epispadias
Epispadias
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Bladder Exstrophy
Bladder Exstrophy
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Hypospadias
Hypospadias
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Urachus Fate
Urachus Fate
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Antegrade flow
Antegrade flow
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Uterovesical Junction (UVJ)
Uterovesical Junction (UVJ)
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Flap-Valve effect
Flap-Valve effect
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Vesico-Ureteral Reflux (VUR)
Vesico-Ureteral Reflux (VUR)
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Obstructive hydronephrosis
Obstructive hydronephrosis
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Primary VUR
Primary VUR
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Secondary VUR
Secondary VUR
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Treatment options for VUR
Treatment options for VUR
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Pronephros
Pronephros
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Mesonephros
Mesonephros
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Metanephros
Metanephros
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Development of the Gut
Development of the Gut
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Anterior Urethral Valves (PUV)
Anterior Urethral Valves (PUV)
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Congenital Uteropelvic Junction Stenosis
Congenital Uteropelvic Junction Stenosis
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Consequences of Hypospadias
Consequences of Hypospadias
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Gubernaculum
Gubernaculum
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Undescended Testis
Undescended Testis
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Diagnosis of Cryptorchidism
Diagnosis of Cryptorchidism
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Causes of Undescended Testis
Causes of Undescended Testis
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Scrotal Problems
Scrotal Problems
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Anatomical Indication
Anatomical Indication
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Functional Obstruction
Functional Obstruction
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Posterior Urethral Valves
Posterior Urethral Valves
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Potter’s Syndrome
Potter’s Syndrome
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VCUG
VCUG
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Hydronephrosis
Hydronephrosis
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Recurrent UTI
Recurrent UTI
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Spinal Dysraphism
Spinal Dysraphism
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Mullerian Ducts
Mullerian Ducts
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Ultrasonography Sign
Ultrasonography Sign
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Study Notes
Embryology of Nephric Systems
- Pronephros is the earliest nephric stage in humans, a vestigial structure developing in the third week and disappearing by the fourth to fifth week of embryonic life.
- Mesonephros is also a transient excretory organ, with cup-like outgrowths (Bowman's) that develop into a knot of capillaries (glomerulus). The mesonephric duct (Wolffian) gives rise to the male reproductive system. The paramesonephric duct (Mullerian) forms the female reproductive ductal system.
- Metanephros gives rise to the mature kidney; it needs stimulation from the ureteral bud. Migration is essential for development.
Development of the Reproductive System
- Testis secretes Mullerian inhibiting substance (MIS), causing regression of the Mullerian ducts.
- Leydig cells produce testosterone, leading to male development.
Vesicoureteral Reflux (VUR)
- International Reflux Classification system categorizes secondary VUR and chronic VUR spectrum.
- Posterior urethral valves (PUV) and Potter's syndrome are related conditions.
Embryology of the Vesicoureteral Unit
- The urogenital sinus plays a crucial role.
- Embryology of the vesicourethral unit includes the formation of the urachus, and anomalies such as epispadias and hypospadias.
Embryogenesis of Testicular Descent
- Factors affecting testicular descent include the gubernaculum and increased intra-abdominal pressure.
- Conditions like cryptorchidism (undescended testis), inguinal hernia, and hydrocele are related to this process.
Horseshoe Kidney
- A horseshoe kidney is an anomaly of kidney position.
- Causes include delayed canalization of the ureteral bud.
Duplicated Ureter
- Incomplete duplex is usually of no clinical consequence.
- Double collecting systems involve the upper pole draining into the lower, more medial ureteral meatus, and the lower pole into the upper, more lateral meatus.
Congenital Uteropelvic Junction (UPJ) Stenosis
- UPJ is a segment of the ureter where the ureteral muscle layer occludes the intramural segment of the ureter, which prevents urine from entering the upper urinary tract, often leading to hydronephrosis, which is the swelling of kidney.
Vesico-Ureteral Reflux (VUR)
- "Retrograde" flow of urine into the upper collecting system.
- Recurrent UTI is associated with this, among other factors.
Spectrum of Chronic VUR
- Recurrent UTI, chronic hypertension and chronic renal failure.
- Posterior urethral valves (PUV) are related.
Potter's Syndrome
- Dysmorphic facial features, fetal growth retardation, and limb deformities are associated.
Urachal Abnormalities
- Urachus is a remnant of the allantoic duct, normally obliterating by the third trimester.
- Urachal abnormalities include fistula, cyst, and diverticulum.
Hypospadias and Epispadias
- Hypospadias involves incomplete urethral fold closure and chordee (bending of the penis).
- Epispadias refers to an abnormal ventral urethral opening.
Abdominal Mass in Children
- Wilms tumor, neuroblastoma, and hepatoblastoma are common malignant tumors.
- Multicystic dysplastic kidney and hydronephrosis are common benign masses.
Neuroblastoma
- Originates from neural crest cells, possibly in the adrenal medulla or sympathetic ganglia, and may occur along the sympathetic chain.
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Description
This quiz covers the embryological development of the nephric systems, including the stages of pronephros, mesonephros, and metanephros. It also explores the relationship between nephric development and the reproductive system. Test your knowledge on vesicoureteral reflux and its classifications.