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Questions and Answers
What structures constitute the primary palate?
What structures constitute the primary palate?
- Two maxillary and two medial nasal processes (correct)
- Frontonasal prominence and two mandibles
- Two maxillary and two lateral nasal processes
- Two medial nasal processes and the palatine uvula
During which weeks of development does the secondary palate form?
During which weeks of development does the secondary palate form?
- Between the 8th and 10th weeks
- Between the 6th and 8th weeks (correct)
- Between the 4th and 6th weeks
- Between the 10th and 12th weeks
What is the role of cranial neural crest cells in facial development?
What is the role of cranial neural crest cells in facial development?
- They contribute to the formation of facial prominences (correct)
- They form the primary palate only
- They are involved in the fusion of the palate only
- They create the nasal pits exclusively
What is formed when the lateral and medial nasal processes fuse?
What is formed when the lateral and medial nasal processes fuse?
How is the definitive palate formed?
How is the definitive palate formed?
At what point in development does the palate begin to form?
At what point in development does the palate begin to form?
Which time period is most critical for palate development?
Which time period is most critical for palate development?
What is the primary palate developed from?
What is the primary palate developed from?
Where does the secondary palate develop from?
Where does the secondary palate develop from?
What anatomical part lies behind the premaxillary part of the maxilla?
What anatomical part lies behind the premaxillary part of the maxilla?
During which weeks do the lateral palatine processes elongate and ascend to a horizontal position above the tongue?
During which weeks do the lateral palatine processes elongate and ascend to a horizontal position above the tongue?
What structure do the lateral palatine processes fuse with during their development?
What structure do the lateral palatine processes fuse with during their development?
When does fusion with the nasal septum begin and complete during fetal development?
When does fusion with the nasal septum begin and complete during fetal development?
What is primarily responsible for the changes in the appearance of the face during the fetal period?
What is primarily responsible for the changes in the appearance of the face during the fetal period?
Which of the following is considered a craniofacial anomaly?
Which of the following is considered a craniofacial anomaly?
What results from the failure of the medial nasal prominences to merge?
What results from the failure of the medial nasal prominences to merge?
Which type of cleft results from the maxillary prominence failing to fuse with the lateral nasal prominence?
Which type of cleft results from the maxillary prominence failing to fuse with the lateral nasal prominence?
What is a common result of cleft palate?
What is a common result of cleft palate?
Which cleft involves both the lip and palate?
Which cleft involves both the lip and palate?
Which cleft type is characterized by the failure of maxillary prominences to meet on both sides?
Which cleft type is characterized by the failure of maxillary prominences to meet on both sides?
What generally does not result from a cleft lip?
What generally does not result from a cleft lip?
What type of cleft leaves the nasal and oral cavities connected?
What type of cleft leaves the nasal and oral cavities connected?
What cleft arises specifically from the failure of the maxillary prominence to merge with the medial nasal prominence on one side?
What cleft arises specifically from the failure of the maxillary prominence to merge with the medial nasal prominence on one side?
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Study Notes
Development of Facial Structure
- Development of the face in mammals originates from five facial prominences around the primitive mouth: frontonasal, maxillary (two), and mandibular (two).
- Cranial neural crest cells, which migrate from the dorsal edge of the rostral neural tube, populate these facial prominences.
- The frontonasal prominence divides into medial and lateral nasal processes due to the formation of nasal pits.
- Fusion of lateral and medial nasal processes leads to nostril formation and the upper lip forms where medial nasal processes meet maxillary prominences.
Palate Development
- The palate separates the nasal and oral cavities, consisting of the primary and secondary palate.
- The primary palate is formed by the maxillary and medial nasal processes and begins development in the 6th week, completing by the 12th week.
- Secondary palate forms between the 6th and 8th weeks from lateral palatine processes of the maxillary processes, eventually creating bilateral fusion to form the definitive palate.
Critical Periods
- The main development of the palate occurs from the end of the 6th week to the beginning of the 9th week.
- The primary palate represents a small portion of the adult hard palate, lying anterior to the incisive fossa.
Changes During Fetal Period
- Changes in facial proportions and positioning occur during the fetal period, resulting in a prominent forehead and characteristic features.
- Nasal and mandibular structures undergo significant changes; initially flat noses become shaped, and the mandible develops further.
- The enlargement of the brain influences the movement of the eyes medially and the ascent of the ears.
Craniofacial Anomalies
- Craniofacial anomalies are congenital deformities affecting the head and facial bones, varying from mild to severe.
- Common examples include cleft lip and palate, caused by improper fusion of embryonic facial prominences, leading to issues in breathing, feeding, swallowing, and speech.
- Types of cleft conditions include median cleft lip, unilateral cleft lip, bilateral cleft lip, oblique facial cleft, and cleft palate, each resulting from distinct developmental failures.
- Unilateral and bilateral cleft lips occur due to failure of maxillary prominence fusion with the medial nasal prominence on one or both sides, respectively. Oblique facial clefts arise from the lack of fusion with the lateral nasal prominence.
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