Obesity Pharmacology

BMI 30.0 + = Qualifies BMI 27.0 = Does Not Qualify BMI 27.0+ with HTN = Qualifies BMI 27.0+ with Dyslipidemia = Qualifies

BMI 30-34.9 with DM or Metabolic Syndrome = Qualifies BMI greater than 35.0 = Does Not Qualify BMI equal/above 35.0 with obesity comorbidity = Qualifies BMI equal/above 40.0 = Qualifies

<p>Phentermine (Adipex-P®) = Short-term stimulant that decreases appetite via norepinephrine and dopamine release Phentermine/Topiramate ER (Qsymia®) = Sympathomimetic/antiepileptic extended release combination that decreases appetite Naltrexone/Bupropion SR (Contrave®) = Opioid antagonist/dopamine and norepinephrine reuptake inhibitor that reduces cravings Orlistat (Xenical®, Alli®) = Inhibits gastric and pancreatic lipases and decreases fat absorption</p> Signup and view all the answers

<p>Phentermine (Adipex-P®) = Twice daily for ages 17 and older Naltrexone/Bupropion SR (Contrave®) = 18+; once daily week one, twice daily week two, 2 in AM and 1 PM week three, 2 BID onwards Phentermine/Topiramate ER (Qsymia®) = Ages 12 and up; start low and increases every 14 days; renal dose of 7.5/46 Orlistat (Xenical®, Alli®) = TID before meals</p> Signup and view all the answers

<p>Naltrexone/Bupropion SR (Contrave®) = Opioid use, uncontrolled HTN, seizure disorder, pregnancy Orlistat (Xenical®, Alli®) = Liver damage (rare), cholelithiasis, increased urinary oxalate/kidney stones Phentermine (Adipex-P®) = Cardiovascular disease (i.e., uncontrolled hypertension), hyperthyroidism, glaucoma, drug abuse, seizure disorder, Tourette’s, MAO inhibitors within the past 14 days Phentermine/Topiramate ER (Qsymia®) = Pregnancy Category X, hypertension, hyperthyroidism, glaucoma, MAO inhibitor within 14 days</p> Signup and view all the answers

<p>Naltrexone/Bupropion SR (Contrave®) = Nausea/vomiting, headache, constipation, dizziness, anxiety Orlistat (Xenical®, Alli®) = Gastrointestinal (flatus with discharge, fatty stool, fecal urgency), Decreased absorption of vitamins ADEK Phentermine (Adipex-P®) = Increased heart rate, increased blood pressure (BP), headache, tremor, anxiety Phentermine/Topiramate ER (Qsymia®) = Tachycardia, CNS effects (i.e., insomnia), increased serum creatinine, hypokalemia, numbness, tingling, dizziness, xerostomia, dysgeusia, headache</p> Signup and view all the answers

<p>Phentermine/Topiramate ER (Qsymia®)</p> Signup and view all the answers

<p>Phentermine/Topiramate ER (Qsymia®)</p> Signup and view all the answers

<p>False</p> Signup and view all the answers

<p>GLP + GIP (liraglutide,semaglutide,tirazepatide)</p> Signup and view all the answers

<p>Liraglutide/Saxenda = Daily injection GLP Semaglutide Wegovy = Weekly GLP Tirazepatide Zepound = Weekly GIP :) = :)</p> Signup and view all the answers

<p>B and C</p> Signup and view all the answers

<p>Insulin, sulfonylureas, levothyroxine</p> Signup and view all the answers

<p>Plenty</p> Signup and view all the answers

<p>CVD/HTN = GIP/GLT (monitor HR), orlistat Depression, Hx of seizures, Opioid use = AVOID naltrexone/bupropion DM2 = All are safe pregnancy = NONE</p> Signup and view all the answers