Carbs 3
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Questions and Answers

What is the main function of ATP synthase?

  • Inhibiting cellular respiration
  • Synthesizing ATP from ADP and Pi (correct)
  • Rotating the enzyme
  • Transporting protons

Which of the following substances can block the Electron Transport Chain (ETC) at Complex IV?

  • Antimycin
  • Carbon monoxide (correct)
  • Dimercaprol
  • Malonate

What is the purpose of UNCOUPLERS in cellular respiration?

  • Increase ATP production
  • Dissociate oxidation from phosphorylation (correct)
  • Generate ATP efficiently
  • Enhance the Electron Transport Chain

Which of the following is NOT an Inhibitor that can block cellular respiration?

<p>Hydrogen sulfide (A)</p> Signup and view all the answers

What type of energy is generated when NADH and FADH2 are oxidized but no ATP is produced?

<p>Heat energy (C)</p> Signup and view all the answers

What is the ultimate product formed when electrons combine with O2 and H+ in the Electron Transport Chain (ETC)?

<p>H2O (C)</p> Signup and view all the answers

Which of the following is NOT a part of the Electron Transport Chain (ETC) complex?

<p>ATP synthase (D)</p> Signup and view all the answers

What type of groups do electron-transporting proteins in the ETC contain?

<p>Iron, Sulfur, Copper (D)</p> Signup and view all the answers

What is the major role of the Electron Transport Chain (ETC) in mammalian cells?

<p>To consume oxygen (C)</p> Signup and view all the answers

In the Electron Transport Chain (ETC), what process occurs when electrons are removed?

<p>Oxidation (D)</p> Signup and view all the answers

Where are H+ ions pumped during the operation of the Electron Transport Chain (ETC)?

<p>Across the inner mitochondrial membrane (A)</p> Signup and view all the answers

What primarily regulates OXPHOS?

<p>ATP/ADP ratio (B)</p> Signup and view all the answers

What is the main function of the Cori Cycle?

<p>Convert lactic acid to glucose in the liver (A)</p> Signup and view all the answers

Which hormone inhibits gluconeogenesis?

<p>Insulin (A)</p> Signup and view all the answers

Which organ in the body stores the highest percentage of glycogen?

<p>Liver (A)</p> Signup and view all the answers

What is NOT a substrate for gluconeogenesis?

<p>Fatty acids (A)</p> Signup and view all the answers

In glycogen metabolism, what is the main role of glycogen synthase?

<p>Starts the glycogen chain (A)</p> Signup and view all the answers

Which enzyme deficiency is associated with glycogen storage diseases?

<p>Glycogenin (A)</p> Signup and view all the answers

Which process supplies the needs for plasma glucose between meals?

<p>Gluconeogenesis (D)</p> Signup and view all the answers

What is the fate of glucogenic amino acids in gluconeogenesis?

<p>Directly converted to glucose (D)</p> Signup and view all the answers

What effect does glucagon have on glycogen metabolism?

<p>Stimulates glycogenolysis and inhibits glycogenesis (C)</p> Signup and view all the answers

What is another name for the Pentose Phosphate Pathway (PPP)?

<p>Hexose Monophosphate Shunt (D)</p> Signup and view all the answers

Where does gluconeogenesis primarily take place?

<p>Liver (B)</p> Signup and view all the answers

What is the primary function of the Pentose Phosphate Pathway (PPP)?

<p>Producing ribose residues for nucleotide biosynthesis (C)</p> Signup and view all the answers

In which of the following tissues is the Pentose Phosphate Pathway (PPP) most active for the biosynthesis of fatty acids?

<p>Liver and adipose tissue (B)</p> Signup and view all the answers

What is the key role of NADP+/NADPH in physiological processes?

<p>Maintaining cellular redox homeostasis (D)</p> Signup and view all the answers

Which process utilizes NADPH to destroy microorganisms in specialized lysosomes?

<p>Respiratory burst in phagocytic cells (C)</p> Signup and view all the answers

What is the significance of NADPH in drug metabolism within the liver?

<p>Activating cytochrome P450 for drug metabolism (D)</p> Signup and view all the answers

Which cell organelle is primarily responsible for producing ROS through activation by NADPH?

<p>Phagolysosome (D)</p> Signup and view all the answers

What is the electron acceptor at the end of the Electron Transport Chain (ETC)?

<p>Water (H2O) (A)</p> Signup and view all the answers

Which of the following is NOT a component of the Electron Transport Chain (ETC) complex?

<p>NADH (C)</p> Signup and view all the answers

What is the major consumer of oxygen in mammalian cells?

<p>Electron Transport Chain (ETC) (B)</p> Signup and view all the answers

Which element is NOT found in the electron-transporting groups within the ETC?

<p>Calcium (A)</p> Signup and view all the answers

During which process are H+ ions pumped across the inner mitochondrial membrane in the Electron Transport Chain (ETC)?

<p>Oxidative phosphorylation (A)</p> Signup and view all the answers

Which of the following is NOT a protein complex within the Electron Transport Chain (ETC)?

<p>Complex II (A)</p> Signup and view all the answers

What is the main role of UNCOUPLERS in cellular respiration?

<p>Dissociate oxidation from phosphorylation, generating heat but not ATP (C)</p> Signup and view all the answers

Which of the following substances can block the Electron Transport Chain (ETC) at Complex III?

<p>Antimycin (D)</p> Signup and view all the answers

What is the primary function of ATP synthase?

<p>To synthesize ATP from ADP and Pi using H+ flow through a proton channel (D)</p> Signup and view all the answers

What effect does cyanide have on cellular respiration?

<p>Blocks Complex IV in the Electron Transport Chain (ETC) (D)</p> Signup and view all the answers

Where is the energy derived from when NADH and FADH2 are oxidized, but no ATP is generated?

<p>Generation of heat only (C)</p> Signup and view all the answers

What primarily regulates gluconeogenesis?

<p>ATP/ADP ratio (C)</p> Signup and view all the answers

Which of the following is a substrate for gluconeogenesis?

<p>Glycerol (C)</p> Signup and view all the answers

What is the fate of glucogenic amino acids in gluconeogenesis?

<p>Conversion to TCA cycle intermediates (B)</p> Signup and view all the answers

Where does gluconeogenesis primarily take place?

<p>Liver (A)</p> Signup and view all the answers

Which hormones stimulate gluconeogenesis?

<p>Glucagon and epinephrine (D)</p> Signup and view all the answers

What is the main function of the Cori Cycle?

<p>Convert lactate to glucose in the liver (A)</p> Signup and view all the answers

Which hormone stimulates glycogenolysis and inhibits glycogenesis in glycogen metabolism regulation?

<p>Epinephrine (B)</p> Signup and view all the answers

What is the primary substrate for gluconeogenesis?

<p>Amino acids (D)</p> Signup and view all the answers

Which enzyme plays a role in glycogen synthesis by elongating the glycogen chain?

<p>Glycogen synthase (D)</p> Signup and view all the answers

What is the primary function of the Pentose Phosphate Pathway (PPP)?

<p>Convert glucose 6-phosphate to ribose-5-phosphate (C)</p> Signup and view all the answers

What can prolonged use of steroids cause related to glycogen storage?

<p>Lead to glycogen storage abnormalities (B)</p> Signup and view all the answers

What is the primary function of the Pentose Phosphate Pathway (PPP)?

<p>Generation of NADPH for reductive biosynthesis (A)</p> Signup and view all the answers

Which physiological process does NADPH play a crucial role in?

<p>Drug metabolism in the liver (A)</p> Signup and view all the answers

Where does the respiratory burst, involving NADPH-oxidase, primarily occur?

<p>Lysosomes (phagolysosome) (D)</p> Signup and view all the answers

In which tissues is the Pentose Phosphate Pathway (PPP) most active for biosynthesis?

<p>Endocrine tissues and mammary gland (D)</p> Signup and view all the answers

What is the role of NADPH in the production of reactive oxygen species (ROS)?

<p>Involved in the destruction of microorganisms (B)</p> Signup and view all the answers

In which cellular process does NADP+/NADPH contribute significantly to redox homeostasis?

<p>Detoxification reactions (A)</p> Signup and view all the answers

What are the building blocks of lipids?

<p>Fatty acids (B)</p> Signup and view all the answers

Which type of lipids have both hydrophilic and hydrophobic parts?

<p>Sphingolipids (A)</p> Signup and view all the answers

Which molecule is a combination of a fatty acid with an alcohol such as glycerol?

<p>Fatty acyl esters (A)</p> Signup and view all the answers

Which lipids are described as nonpolar molecules?

<p>Waxes (C)</p> Signup and view all the answers

What aspect of fatty acids makes them highly water insoluble?

<p>Long-chain-length structure (C)</p> Signup and view all the answers

Which structural feature causes a fatty acid to bend or kink?

<p>Presence of a cis double bond (D)</p> Signup and view all the answers

What effect does adding double bonds to a fatty acid have on its melting temperature?

<p>Decreases the melting temperature (C)</p> Signup and view all the answers

In which form are more than 90% of fatty acids found when circulating in blood plasma?

<p>Esterified form in lipoproteins (A)</p> Signup and view all the answers

Which type of fatty acid plays important roles in plasma membrane structure?

<p>Saturated fatty acids (D)</p> Signup and view all the answers

What is the primary factor making fatty acids amphipathic in nature?

<p>Hydrophilic anionic group at one end (C)</p> Signup and view all the answers

Which carbon in a fatty acid chain is also known as the -carbon?

<p>Carbon 2 (B)</p> Signup and view all the answers

What is the term used for fatty acids with 13-21 carbons?

<p>Long-chain fatty acids (C)</p> Signup and view all the answers

Which end of a fatty acid chain is used as a reference point to name double bonds?

<p>δ end (C)</p> Signup and view all the answers

What is the term for fatty acids with 6-12 carbons?

<p>Medium-chain fatty acids (B)</p> Signup and view all the answers

Arachidonic acid is classified as an -6 fatty acid because:

<p>The first double bond is six carbons from the α end. (A)</p> Signup and view all the answers

Which type of phospholipids contain sphingosine as their backbone?

<p>Sphingophospholipids (A)</p> Signup and view all the answers

What is the main function of sphingomyelin in the body?

<p>Component of myelin sheath (B)</p> Signup and view all the answers

Which alcohol group is esterified with phosphatidic acid to form phosphatidylglycerol?

<p>Glycerol (B)</p> Signup and view all the answers

What is the precursor of glycerophospholipids that is esterified to different alcohols to form various types of phospholipids?

<p>Phosphatidic acid (C)</p> Signup and view all the answers

Which phospholipid is important for regulating intracellular signaling, lipid transportation, and vesicular trafficking?

<p>Phosphatidylinositol (C)</p> Signup and view all the answers

What is the major component of lecithin among glycerophospholipids?

<p>Phosphatidylcholine (B)</p> Signup and view all the answers

What is the primary function of cholesterol in the body?

<p>Serves as a structural component of cell membranes and lipoproteins (B)</p> Signup and view all the answers

Where are cholesteryl esters (CE) primarily found?

<p>In association with lipoproteins (D)</p> Signup and view all the answers

Which statement accurately describes the synthesis of cholesterol?

<p>Cholesterol synthesis involves the attachment of fatty acids at carbon 3 (B)</p> Signup and view all the answers

What is the significance of cholesterol entering the liver from various sources?

<p>It is a precursor of bile salts (B)</p> Signup and view all the answers

In the context of cholesterol homeostasis, what happens if there are disturbances in the delicate balance?

<p>Deposition of cholesterol in tissues and plaque formations (C)</p> Signup and view all the answers

What is the role of the liver in controlling cholesterol homeostasis?

<p>Regulation of cholesterol synthesis and excretion (D)</p> Signup and view all the answers
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