Eicosanoids and Arachidonic Acid Quiz
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Questions and Answers

Which fatty acid is the most abundant precursor of eicosanoids?

  • Stearic acid
  • Arachidonic acid (correct)
  • Oleic acid
  • Linoleic acid
  • Which type of lipase is most dominant in the acute release of arachidonic acid?

  • Phospholipase C
  • Cytosolic (c) PLA2 (correct)
  • Secretory (S) PLA2
  • Calcium-independent (i) PLA2
  • Which enzyme is involved in sustained or intense stimulation of arachidonic acid production?

  • P450 epoxygenase
  • Cyclooxygenase (COX)
  • Secretory (S) PLA2 (correct)
  • Lipoxygenase
  • Which of the following is NOT a route for arachidonic acid oxygenation?

    <p>Phospholipase C</p> Signup and view all the answers

    What factors determine the type of eicosanoids synthesized?

    <p>The substrate lipid species</p> Signup and view all the answers

    True or false: Eicosanoids are only found in animals.

    <p>False</p> Signup and view all the answers

    True or false: Arachidonic acid is a 20-carbon fatty acid.

    <p>True</p> Signup and view all the answers

    True or false: Phospholipase C and diglyceride lipase can release arachidonic acid from membrane phospholipids.

    <p>True</p> Signup and view all the answers

    True or false: Arachidonic acid can be oxygenated by five separate routes.

    <p>False</p> Signup and view all the answers

    True or false: The type of eicosanoids synthesized is determined by the type of cell.

    <p>True</p> Signup and view all the answers

    Study Notes

    Eicosanoids and Arachidonic Acid

    • Arachidonic acid is the most abundant precursor of eicosanoids.
    • Cytosolic phospholipase A2 is the most dominant type of lipase in the acute release of arachidonic acid.
    • Phospholipase A2 is involved in sustained or intense stimulation of arachidonic acid production.

    Arachidonic Acid Oxygenation

    • One route that is NOT involved in arachidonic acid oxygenation is direct degradation by oxygenases.

    Eicosanoid Synthesis

    • The type of eicosanoids synthesized is determined by factors such as the type of cell, substrate availability, and the enzyme pathway.
    • The type of cell is a factor that determines the type of eicosanoids synthesized.

    General Facts

    • Arachidonic acid is a 20-carbon fatty acid.
    • Eicosanoids are not unique to animals and can be found in other organisms.
    • Phospholipase C and diglyceride lipase can release arachidonic acid from membrane phospholipids.
    • Arachidonic acid can be oxygenated by five separate routes.

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    Description

    Test your knowledge on eicosanoids and their role as oxygenation products of polyunsaturated long-chained fatty acids. Learn about the abundant precursor, arachidonic acid, and the process of its release from membrane phospholipids.

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