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Mechanisms of Ageing (1)

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8 Questions

What does parabiosis do?

Rejuvenate blood/stem cell function in aged specimen

What is the example of hormones modulating ageing?

Mice over expressing GH age faster

What are short telomeres recognised as?

DNA damage

What is the stage where irreversible cell cycle arrest occurs?

G1/S

Why do telomeres become short?

Primer removal for DNA polymerase

What is the telomere repetitive DNA sequence?

TTAGGG

Mice with short telomeres have a

Longer lifespan

Telomere shortening is an example of what theory of ageing?

Antagonistic pleiotropy - telomere shortening acts as a tumour suppressor mechanic at a young age

Test your knowledge about cell ageing, telomeres, and related concepts. This quiz covers topics such as parabiosis, hormones modulating ageing, short telomeres, irreversible cell cycle arrest, telomere shortening, and the telomere repetitive DNA sequence.

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